DK2320997T3 - Apparat til forbedring af nervevævs operation - Google Patents

Apparat til forbedring af nervevævs operation Download PDF

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Publication number
DK2320997T3
DK2320997T3 DK09745760.0T DK09745760T DK2320997T3 DK 2320997 T3 DK2320997 T3 DK 2320997T3 DK 09745760 T DK09745760 T DK 09745760T DK 2320997 T3 DK2320997 T3 DK 2320997T3
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DK
Denmark
Prior art keywords
stimulation
agent
electrode
nerve
electrodes
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Application number
DK09745760.0T
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English (en)
Inventor
Stefan Dietrich
Christoph Beck
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Cerbomed Gmbh
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Publication of DK2320997T3 publication Critical patent/DK2320997T3/da

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36017External stimulators, e.g. with patch electrodes with leads or electrodes penetrating the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/36014External stimulators, e.g. with patch electrodes
    • A61N1/36025External stimulators, e.g. with patch electrodes for treating a mental or cerebral condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36082Cognitive or psychiatric applications, e.g. dementia or Alzheimer's disease
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61NELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00Electrotherapy; Circuits therefor
    • A61N1/18Applying electric currents by contact electrodes
    • A61N1/32Applying electric currents by contact electrodes alternating or intermittent currents
    • A61N1/36Applying electric currents by contact electrodes alternating or intermittent currents for stimulation
    • A61N1/3605Implantable neurostimulators for stimulating central or peripheral nerve system
    • A61N1/3606Implantable neurostimulators for stimulating central or peripheral nerve system adapted for a particular treatment
    • A61N1/36114Cardiac control, e.g. by vagal stimulation

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Hospice & Palliative Care (AREA)
  • Developmental Disabilities (AREA)
  • Child & Adolescent Psychology (AREA)
  • Neurosurgery (AREA)
  • Social Psychology (AREA)
  • Cardiology (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines Containing Plant Substances (AREA)

Claims (6)

1. Middel til stimulering af nervevæv, hvilket middel til stimulering af nervevæv er beregnet til at levere stimuli, gennem hvilke lokale perfusionsændringer, der er forbundet med nerveaktivitet, såvel som elektro-neuro-kemiske, biokemiske, neuromodulerende eller neuroplastiske responser og/eller forandringer i interaktionsprocesser af typen "metabolismeforsyningslinjer - nervevæv" i hvirveldyr kan sættes i gang og/eller påvirkes, hvori de stimuli, som kan leveres af midlet til stimulering af nervevæv, er elektriske stimuli, hvori midlet er beregnet til at stimulere Ramus auricularis Nervi ved det ydre øre og/eller den ydre øregang, hvori midlet omfatter et acrylhus (5) for et elektrodearrangement, hvilket acrylhus er beregnet til at blive placeret på indersiden af tragus i det venstre ydre øre og rummer en stimuleringselektrode (2) og en referenceelektrode (3) , hvori midlet desuden omfatter en selvstændig elektrisk nervestimulator (4), og kendetegnet ved, at stimuleringselektroden (2) er en stmuleringselektrode af sterling sølv, og elektroderne (2) , (3) er flade overfladeelektroder, hvori den selvstændige elektriske nervestimulator (4) er forbundet med kulfibertråde til de elektroder (2, 3) , der er placeret i acrylhuset (5) for et elektrodearrangement, og er beregnet til at levere en stimulus som en monofase-modificeret rektangulær impuls med en pulsbredde på 250 ms og en variabel amplitude på mellem 4 og 8 mA og en stimuleringsfrekvens på 25 Hz .
2. Middel ifølge krav 1, kendetegnet ved, at stimuliene genererer aktionspotentialer, der udbreder sig i én retning.
3. Middel ifølge krav 1 eller 2, kendetegnet ved, at stimuleringspulsen som en monofase-modificeret rektangulær impuls efterfølges øjeblikkeligt af en ladningsgenvindingsfase med en justerbar varighed.
4. Middel ifølge krav 3, kendetegnet ved, at stimuleringskarakteristikken spejles.
5. Middel ifølge et hvilket som helst af de foregående krav, hvori midlet til stimulering af nervevæv omfatter et individuelt fremstillet ørestykke.
6. Middel ifølge et hvilket som helst af de foregående krav, hvori elektroderne (2, 3) omfatter kontaktsteder (8, 9) med en indbyrdes afstand på 8 mm.
DK09745760.0T 2008-05-13 2009-05-13 Apparat til forbedring af nervevævs operation DK2320997T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US5270508P 2008-05-13 2008-05-13
PCT/EP2009/055777 WO2009138428A2 (en) 2008-05-13 2009-05-13 Method to enhance neutral tissue operation

Publications (1)

Publication Number Publication Date
DK2320997T3 true DK2320997T3 (da) 2016-02-29

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Country Status (9)

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US (1) US8506469B2 (da)
EP (1) EP2320997B1 (da)
BR (1) BRPI0912602A2 (da)
CA (1) CA2724234A1 (da)
DK (1) DK2320997T3 (da)
ES (1) ES2563634T3 (da)
MX (1) MX2010012372A (da)
PL (1) PL2320997T3 (da)
WO (1) WO2009138428A2 (da)

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US8506469B2 (en) 2013-08-13
US20090287035A1 (en) 2009-11-19
PL2320997T3 (pl) 2016-05-31
EP2320997A1 (en) 2011-05-18
BRPI0912602A2 (pt) 2019-06-04
CA2724234A1 (en) 2009-11-19
WO2009138428A2 (en) 2009-11-19
EP2320997B1 (en) 2015-11-25
ES2563634T3 (es) 2016-03-15
MX2010012372A (es) 2011-02-22

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