DK2307042T3 - Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerte - Google Patents

Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerte

Info

Publication number
DK2307042T3
DK2307042T3 DK09768854.3T DK09768854T DK2307042T3 DK 2307042 T3 DK2307042 T3 DK 2307042T3 DK 09768854 T DK09768854 T DK 09768854T DK 2307042 T3 DK2307042 T3 DK 2307042T3
Authority
DK
Denmark
Prior art keywords
trpv
pain
module
treatment
receptor system
Prior art date
Application number
DK09768854.3T
Other languages
English (en)
Inventor
R Anders Nykj
V Gter Christian Bjerggaard
Ole J Bjerrum
Pernille Jansen
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of DK2307042T3 publication Critical patent/DK2307042T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • A01K2217/052Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/105Murine
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00Screening for compounds of potential therapeutic value

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK09768854.3T 2008-06-25 2009-06-24 Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerte DK2307042T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7562708P 2008-06-25 2008-06-25
DKPA200800880 2008-06-25
PCT/DK2009/050143 WO2009155932A2 (en) 2008-06-25 2009-06-24 Modulation of the trpv : vps10p-domain receptor system for the treatment of pain

Publications (1)

Publication Number Publication Date
DK2307042T3 true DK2307042T3 (da) 2014-05-12

Family

ID=41445008

Family Applications (2)

Application Number Title Priority Date Filing Date
DK14154831.3T DK2732823T3 (da) 2008-06-25 2009-06-24 Modulering af TrpV : Vps10p-domæne-receptorsystemet til behandlingen af smerte
DK09768854.3T DK2307042T3 (da) 2008-06-25 2009-06-24 Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerte

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK14154831.3T DK2732823T3 (da) 2008-06-25 2009-06-24 Modulering af TrpV : Vps10p-domæne-receptorsystemet til behandlingen af smerte

Country Status (5)

Country Link
US (1) US8460657B2 (da)
EP (2) EP2732823B1 (da)
DK (2) DK2732823T3 (da)
ES (1) ES2464459T3 (da)
WO (1) WO2009155932A2 (da)

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EP3225251B1 (en) * 2006-12-21 2020-02-12 H. Lundbeck A/S Modulation of activity of proneurotrophins
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CN101939337B (zh) 2008-02-04 2016-03-09 雷莱恩基因组有限公司 抗trka抗体及其衍生物
US8058406B2 (en) 2008-07-09 2011-11-15 Biogen Idec Ma Inc. Composition comprising antibodies to LINGO or fragments thereof
CN103339149B (zh) * 2010-06-14 2016-02-03 H.隆德贝克有限公司 SorLA和GDNF-家族配体受体之间的相互作用的调节
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US11214610B2 (en) 2010-12-01 2022-01-04 H. Lundbeck A/S High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris
US9539324B2 (en) 2010-12-01 2017-01-10 Alderbio Holdings, Llc Methods of preventing inflammation and treating pain using anti-NGF compositions
US9067988B2 (en) 2010-12-01 2015-06-30 Alderbio Holdings Llc Methods of preventing or treating pain using anti-NGF antibodies
US9783602B2 (en) 2010-12-01 2017-10-10 Alderbio Holdings Llc Anti-NGF compositions and use thereof
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DK3466930T3 (da) 2013-02-08 2022-09-05 Gen Mills Inc Fødevareprodukt med reduceret natriumindhold
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CA2973266A1 (en) 2015-01-08 2016-07-14 Biogen Ma Inc. Lingo-1 antagonists and uses for treatment of demyelinating disorders
WO2016164608A1 (en) 2015-04-07 2016-10-13 Alector Llc Methods of screening for sortilin binding antagonists
IL254887B2 (en) 2015-04-07 2023-11-01 Alector Llc Anti-sortilin antibodies and methods of using them
WO2017101956A1 (en) * 2015-12-18 2017-06-22 Aarhus Universitet SorCS PEPTIDES AND USES THEREOF
US11396546B2 (en) 2018-07-13 2022-07-26 Alector Llc Anti-Sortilin antibodies and methods of use thereof

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Also Published As

Publication number Publication date
WO2009155932A3 (en) 2010-04-22
EP2732823B1 (en) 2019-08-07
US8460657B2 (en) 2013-06-11
ES2464459T3 (es) 2014-06-02
EP2732823A1 (en) 2014-05-21
WO2009155932A2 (en) 2009-12-30
DK2732823T3 (da) 2019-09-16
US20110142830A1 (en) 2011-06-16
EP2307042B1 (en) 2014-03-26
EP2307042A2 (en) 2011-04-13

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