DK2307042T3 - Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerte - Google Patents
Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerteInfo
- Publication number
- DK2307042T3 DK2307042T3 DK09768854.3T DK09768854T DK2307042T3 DK 2307042 T3 DK2307042 T3 DK 2307042T3 DK 09768854 T DK09768854 T DK 09768854T DK 2307042 T3 DK2307042 T3 DK 2307042T3
- Authority
- DK
- Denmark
- Prior art keywords
- trpv
- pain
- module
- treatment
- receptor system
- Prior art date
Links
- 102000003563 TRPV Human genes 0.000 title 1
- 108060008564 TRPV Proteins 0.000 title 1
- 102000005962 receptors Human genes 0.000 title 1
- 108020003175 receptors Proteins 0.000 title 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
- A61K38/179—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
- A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
- A01K2217/052—Animals comprising random inserted nucleic acids (transgenic) inducing gain of function
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2227/00—Animals characterised by species
- A01K2227/10—Mammal
- A01K2227/105—Murine
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2500/00—Screening for compounds of potential therapeutic value
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Neurology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7562708P | 2008-06-25 | 2008-06-25 | |
DKPA200800880 | 2008-06-25 | ||
PCT/DK2009/050143 WO2009155932A2 (en) | 2008-06-25 | 2009-06-24 | Modulation of the trpv : vps10p-domain receptor system for the treatment of pain |
Publications (1)
Publication Number | Publication Date |
---|---|
DK2307042T3 true DK2307042T3 (da) | 2014-05-12 |
Family
ID=41445008
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK14154831.3T DK2732823T3 (da) | 2008-06-25 | 2009-06-24 | Modulering af TrpV : Vps10p-domæne-receptorsystemet til behandlingen af smerte |
DK09768854.3T DK2307042T3 (da) | 2008-06-25 | 2009-06-24 | Modulering af trpv: vps10p-domænereceptorsystem til behandlingen af smerte |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK14154831.3T DK2732823T3 (da) | 2008-06-25 | 2009-06-24 | Modulering af TrpV : Vps10p-domæne-receptorsystemet til behandlingen af smerte |
Country Status (5)
Country | Link |
---|---|
US (1) | US8460657B2 (da) |
EP (2) | EP2732823B1 (da) |
DK (2) | DK2732823T3 (da) |
ES (1) | ES2464459T3 (da) |
WO (1) | WO2009155932A2 (da) |
Families Citing this family (25)
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WO2004085648A2 (en) | 2003-03-19 | 2004-10-07 | Biogen Idec Ma Inc. | Nogo receptor binding protein |
PT1776136E (pt) | 2004-06-24 | 2012-12-05 | Biogen Idec Inc | Tratamento de estados que envolvem desmielinização |
CN101495509B (zh) | 2005-07-08 | 2015-04-22 | 比奥根艾迪克Ma公司 | Sp35抗体及其用途 |
US8642040B2 (en) * | 2006-07-24 | 2014-02-04 | Biogen Idec Ma Inc. | Methods for promoting myelination, neuronal survival and oligodendrocyte differentiation via administration of Sp35 or TrkA antagonists |
EP3225251B1 (en) * | 2006-12-21 | 2020-02-12 | H. Lundbeck A/S | Modulation of activity of proneurotrophins |
CA2701189C (en) * | 2007-10-11 | 2017-05-16 | Biogen Idec Ma Inc. | Methods for treating pressure induced optic neuropathy, preventing neuronal degeneration and promoting neuronal cell survival via administration of lingo-1 antagonists and trkb agonists |
CA2702630C (en) * | 2007-11-08 | 2017-11-21 | Biogen Idec Ma Inc. | Use of lingo-4 antagonists in the treatment of conditions involving demyelination |
CN101939337B (zh) | 2008-02-04 | 2016-03-09 | 雷莱恩基因组有限公司 | 抗trka抗体及其衍生物 |
US8058406B2 (en) | 2008-07-09 | 2011-11-15 | Biogen Idec Ma Inc. | Composition comprising antibodies to LINGO or fragments thereof |
CN103339149B (zh) * | 2010-06-14 | 2016-02-03 | H.隆德贝克有限公司 | SorLA和GDNF-家族配体受体之间的相互作用的调节 |
US9884909B2 (en) | 2010-12-01 | 2018-02-06 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
US11214610B2 (en) | 2010-12-01 | 2022-01-04 | H. Lundbeck A/S | High-purity production of multi-subunit proteins such as antibodies in transformed microbes such as Pichia pastoris |
US9539324B2 (en) | 2010-12-01 | 2017-01-10 | Alderbio Holdings, Llc | Methods of preventing inflammation and treating pain using anti-NGF compositions |
US9067988B2 (en) | 2010-12-01 | 2015-06-30 | Alderbio Holdings Llc | Methods of preventing or treating pain using anti-NGF antibodies |
US9783602B2 (en) | 2010-12-01 | 2017-10-10 | Alderbio Holdings Llc | Anti-NGF compositions and use thereof |
US9078878B2 (en) | 2010-12-01 | 2015-07-14 | Alderbio Holdings Llc | Anti-NGF antibodies that selectively inhibit the association of NGF with TrkA, without affecting the association of NGF with p75 |
CA2873623C (en) | 2012-05-14 | 2021-11-09 | Biogen Idec Ma Inc. | Lingo-2 antagonists for treatment of conditions involving motor neurons |
EP2948147B1 (en) | 2013-01-28 | 2019-03-13 | H. Lundbeck A/S | N-substituted-5-substituted phthalamic acids as sortilin inhibitors |
DK3466930T3 (da) | 2013-02-08 | 2022-09-05 | Gen Mills Inc | Fødevareprodukt med reduceret natriumindhold |
WO2015112083A1 (en) | 2014-01-23 | 2015-07-30 | Biogaia Ab | Selection of agents modulating gastrointestinal pain |
CA2973266A1 (en) | 2015-01-08 | 2016-07-14 | Biogen Ma Inc. | Lingo-1 antagonists and uses for treatment of demyelinating disorders |
WO2016164608A1 (en) | 2015-04-07 | 2016-10-13 | Alector Llc | Methods of screening for sortilin binding antagonists |
IL254887B2 (en) | 2015-04-07 | 2023-11-01 | Alector Llc | Anti-sortilin antibodies and methods of using them |
WO2017101956A1 (en) * | 2015-12-18 | 2017-06-22 | Aarhus Universitet | SorCS PEPTIDES AND USES THEREOF |
US11396546B2 (en) | 2018-07-13 | 2022-07-26 | Alector Llc | Anti-Sortilin antibodies and methods of use thereof |
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2009
- 2009-06-24 DK DK14154831.3T patent/DK2732823T3/da active
- 2009-06-24 WO PCT/DK2009/050143 patent/WO2009155932A2/en active Application Filing
- 2009-06-24 ES ES09768854.3T patent/ES2464459T3/es active Active
- 2009-06-24 DK DK09768854.3T patent/DK2307042T3/da active
- 2009-06-24 EP EP14154831.3A patent/EP2732823B1/en active Active
- 2009-06-24 US US13/000,854 patent/US8460657B2/en active Active
- 2009-06-24 EP EP09768854.3A patent/EP2307042B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
WO2009155932A3 (en) | 2010-04-22 |
EP2732823B1 (en) | 2019-08-07 |
US8460657B2 (en) | 2013-06-11 |
ES2464459T3 (es) | 2014-06-02 |
EP2732823A1 (en) | 2014-05-21 |
WO2009155932A2 (en) | 2009-12-30 |
DK2732823T3 (da) | 2019-09-16 |
US20110142830A1 (en) | 2011-06-16 |
EP2307042B1 (en) | 2014-03-26 |
EP2307042A2 (en) | 2011-04-13 |
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