DK220789D0 - THE USE AND ITS USE TO REDUCE TNF SIDE EFFECTS - Google Patents

THE USE AND ITS USE TO REDUCE TNF SIDE EFFECTS

Info

Publication number
DK220789D0
DK220789D0 DK220789A DK220789A DK220789D0 DK 220789 D0 DK220789 D0 DK 220789D0 DK 220789 A DK220789 A DK 220789A DK 220789 A DK220789 A DK 220789A DK 220789 D0 DK220789 D0 DK 220789D0
Authority
DK
Denmark
Prior art keywords
side effects
reduce tnf
tnfs
tnf
reduce
Prior art date
Application number
DK220789A
Other languages
Danish (da)
Other versions
DK220789A (en
Inventor
Hubert Heuer
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of DK220789D0 publication Critical patent/DK220789D0/en
Publication of DK220789A publication Critical patent/DK220789A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/191Tumor necrosis factors [TNF], e.g. lymphotoxin [LT], i.e. TNF-beta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00General protective or antinoxious agents
    • A61P39/02Antidotes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Paper (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Separation Of Suspended Particles By Flocculating Agents (AREA)

Abstract

Concomitant administration of TNFs with a PAF antagonist allows the unwanted side effects of the TNFs to be reduced and the therapeutic index of the TNFs to be increased.
DK220789A 1988-05-11 1989-05-05 THE USE AND ITS USE TO REDUCE TNF SIDE EFFECTS DK220789A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3816169A DE3816169A1 (en) 1988-05-11 1988-05-11 USE AND AGENT FOR REDUCING THE SIDE EFFECTS OF TNF

Publications (2)

Publication Number Publication Date
DK220789D0 true DK220789D0 (en) 1989-05-05
DK220789A DK220789A (en) 1989-11-12

Family

ID=6354207

Family Applications (1)

Application Number Title Priority Date Filing Date
DK220789A DK220789A (en) 1988-05-11 1989-05-05 THE USE AND ITS USE TO REDUCE TNF SIDE EFFECTS

Country Status (13)

Country Link
EP (1) EP0341558B1 (en)
JP (1) JP2709139B2 (en)
KR (1) KR900017592A (en)
AT (1) ATE78695T1 (en)
AU (1) AU614607B2 (en)
CA (1) CA1336825C (en)
DE (2) DE3816169A1 (en)
DK (1) DK220789A (en)
ES (1) ES2042864T3 (en)
GR (1) GR3005387T3 (en)
HU (1) HUT52381A (en)
IL (1) IL90206A0 (en)
ZA (1) ZA893259B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3735525C2 (en) * 1987-10-20 1997-02-20 Korth Ruth Maria Method for determining the efficacy of paf-acether receptor antagonists
GB8926611D0 (en) * 1989-11-24 1990-01-17 Xenova Ltd Compound and its use

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0287633B1 (en) * 1986-10-16 1993-07-07 The President And Fellows Of Harvard College Combinations of tumor necrosis factors and anti-inflammatory agents for treating malignant and non-malignant diseases

Also Published As

Publication number Publication date
ATE78695T1 (en) 1992-08-15
AU614607B2 (en) 1991-09-05
CA1336825C (en) 1995-08-29
JPH0276825A (en) 1990-03-16
AU3406489A (en) 1989-11-16
DK220789A (en) 1989-11-12
EP0341558A2 (en) 1989-11-15
IL90206A0 (en) 1989-12-15
ES2042864T3 (en) 1993-12-16
DE3816169A1 (en) 1989-11-23
HUT52381A (en) 1990-07-28
EP0341558A3 (en) 1990-05-09
DE58901920D1 (en) 1992-09-03
JP2709139B2 (en) 1998-02-04
ZA893259B (en) 1991-01-30
KR900017592A (en) 1990-12-19
GR3005387T3 (en) 1993-05-24
EP0341558B1 (en) 1992-07-29

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment