DK2166845T3 - ALFA-connexin C-terminal (ACT) peptides FOR THE TREATMENT OF AGE-related macular degeneration - Google Patents

ALFA-connexin C-terminal (ACT) peptides FOR THE TREATMENT OF AGE-related macular degeneration Download PDF

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Publication number
DK2166845T3
DK2166845T3 DK08771766.6T DK08771766T DK2166845T3 DK 2166845 T3 DK2166845 T3 DK 2166845T3 DK 08771766 T DK08771766 T DK 08771766T DK 2166845 T3 DK2166845 T3 DK 2166845T3
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seq
leu
lys
ser
artificial sequence
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DK08771766.6T
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Danish (da)
English (en)
Inventor
Baerbel Rohrer
Robert Gourdie
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Musc Found For Res Dev
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Publication of DK2166845T3 publication Critical patent/DK2166845T3/en

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
DK08771766.6T 2007-06-21 2008-06-23 ALFA-connexin C-terminal (ACT) peptides FOR THE TREATMENT OF AGE-related macular degeneration DK2166845T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US94549307P 2007-06-21 2007-06-21
PCT/US2008/067944 WO2008157840A2 (en) 2007-06-21 2008-06-23 Alpha connexin c-terminal (act) peptides for treating age-related macular degeneration

Publications (1)

Publication Number Publication Date
DK2166845T3 true DK2166845T3 (en) 2016-02-01

Family

ID=40156983

Family Applications (1)

Application Number Title Priority Date Filing Date
DK08771766.6T DK2166845T3 (en) 2007-06-21 2008-06-23 ALFA-connexin C-terminal (ACT) peptides FOR THE TREATMENT OF AGE-related macular degeneration

Country Status (5)

Country Link
US (2) US20110130345A1 (enExample)
EP (1) EP2166845B1 (enExample)
JP (1) JP5552048B2 (enExample)
DK (1) DK2166845T3 (enExample)
WO (1) WO2008157840A2 (enExample)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9408381B2 (en) 2004-12-21 2016-08-09 Musc Foundation For Research Development Alpha Connexin c-Terminal (ACT) peptides for use in transplant
HUE038099T2 (hu) 2004-12-21 2018-09-28 Musc Found For Res Dev Kompozíciók és módszerek sebgyógyulás és szöveti regeneráció elõsegítésére
US20100286762A1 (en) * 2009-03-18 2010-11-11 Musc Foundation For Research Development Compositions and Methods for Ameliorating Clinical Electrical Disturbances
CN104271142B (zh) 2012-03-01 2017-07-04 福斯特斯特林研究公司 含有α连接蛋白C‑末端(ACT)肽的局部凝胶
WO2013163423A1 (en) 2012-04-25 2013-10-31 Musc Foundation For Research Development Compositions and methods for wound healing and tissue repair
AU2014249045A1 (en) * 2013-03-11 2015-10-29 University Of Florida Research Foundation, Inc. Delivery of CARD protein as therapy for occular inflammation
EP3107939B1 (en) 2014-02-19 2020-06-17 University of Florida Research Foundation, Inc. Delivery of nrf2 as therapy for protection against reactive oxygen species
WO2015138628A1 (en) 2014-03-11 2015-09-17 University Of Florida Research Foundation, Inc. Use of aav-expressed m013 protein as an anti-inflammatory therapeutic
JP6683686B2 (ja) * 2014-08-22 2020-04-22 オークランド ユニサービシーズ リミティド チャネル調節剤
JP7185655B2 (ja) * 2014-08-22 2022-12-07 オークランド ユニサービシーズ リミティド チャネル調節剤
ES2804039A1 (es) * 2019-07-30 2021-02-02 Fund Profesor Novoa Santos Fragmentos peptidicos de cx43 para su uso como agentes senoliticos
EP4232157A4 (en) * 2020-10-22 2024-08-28 Xequel Bio, Inc. PEPTIDE FORMULATIONS AND ASSOCIATED OPHTHALMIC USES
US20250302911A1 (en) * 2022-05-13 2025-10-02 Character Biosciences, Inc. Therapeutic lipid processing compositions and methods for treating age-related macular degeneration

Family Cites Families (16)

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Publication number Priority date Publication date Assignee Title
FR1601438A (enExample) 1968-10-17 1970-08-24
US5234809A (en) * 1989-03-23 1993-08-10 Akzo N.V. Process for isolating nucleic acid
FR2739621B1 (fr) * 1995-10-05 1997-12-05 Centre Nat Rech Scient Peptides utilisables comme vecteurs pour l'adressage intracellulaire de molecules actives
CA2361251C (en) * 1999-01-27 2011-03-08 David L. Becker Formulations comprising antisense nucleotides to connexins
US7250397B2 (en) * 2000-02-23 2007-07-31 Zealand Pharma A/S Antiarrhythmic peptides
WO2002088370A2 (en) * 2001-04-30 2002-11-07 Protiva Biotherapeutics Inc. Autogene nucleic acids encoding a secretable rna polymerase
US20050053918A1 (en) * 2001-05-16 2005-03-10 Technion Research & Development Foundation Ltd. Method of identifying peptides capable of binding to MHC molecules, peptides identified thereby and their uses
US6867283B2 (en) * 2001-05-16 2005-03-15 Technion Research & Development Foundation Ltd. Peptides capable of binding to MHC molecules, cells presenting such peptides, and pharmaceutical compositions comprising such peptides and/or cells
US6685971B2 (en) * 2001-06-28 2004-02-03 Rongxiang Xu Method and composition for repairing and promoting regeneration of mucosal tissue in the gastrointestinal tract
CN1827766B (zh) * 2001-06-28 2010-08-25 徐荣祥 体外细胞的培养方法
JP2003238441A (ja) * 2002-02-08 2003-08-27 英行 ▲高▼野 血管新生抑制剤
US20030215424A1 (en) * 2002-05-15 2003-11-20 Seul Kyung Hwan Method of modulating angiogenesis
WO2004073616A2 (en) * 2003-02-14 2004-09-02 Human Matrix Sciences Llc Elastin digest compositions and methods utilizing same
JP5838017B2 (ja) * 2003-12-03 2015-12-24 コーダ セラピューティクス, インコーポレイテッド コネキシンに対して標的化されたアンチセンス化合物およびその使用方法
HUE038099T2 (hu) * 2004-12-21 2018-09-28 Musc Found For Res Dev Kompozíciók és módszerek sebgyógyulás és szöveti regeneráció elõsegítésére
EP2662088A3 (en) * 2005-02-03 2014-02-19 Coda Therapeutics Limited Anti-connexin compounds and uses thereof

Also Published As

Publication number Publication date
JP5552048B2 (ja) 2014-07-16
EP2166845A2 (en) 2010-03-31
US20110130345A1 (en) 2011-06-02
EP2166845B1 (en) 2015-10-21
EP2166845A4 (en) 2012-08-01
US20140018305A1 (en) 2014-01-16
JP2010530903A (ja) 2010-09-16
WO2008157840A3 (en) 2009-02-12
WO2008157840A2 (en) 2008-12-24

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