DK200200624A - The polypeptide composition - Google Patents

The polypeptide composition Download PDF

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Publication number
DK200200624A
DK200200624A DK200200624A DKPA200200624A DK200200624A DK 200200624 A DK200200624 A DK 200200624A DK 200200624 A DK200200624 A DK 200200624A DK PA200200624 A DKPA200200624 A DK PA200200624A DK 200200624 A DK200200624 A DK 200200624A
Authority
DK
Denmark
Prior art keywords
polypeptide composition
polypeptide
composition
organic acid
amount
Prior art date
Application number
DK200200624A
Other languages
Danish (da)
Inventor
Shakhmatova Elena Lliinichna
Prutskova Nataliya Pavlovna
Uliyanova Mariya Viktorovna
Vanchugova Ljudmila Vitalievna
Staroseltseva L Konstantinovna
Knyazhev Vladimi Alexandrovich
Natochin Jury Viktorovich
Plate Nikolai Alfredovich
Valuev Lev Ivanovich
Sytov Gennady Alexeevich
Jay Henis
Original Assignee
Inst Neftechimicheskogo Sintez
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from RU99122655A external-priority patent/RU2171687C2/en
Application filed by Inst Neftechimicheskogo Sintez filed Critical Inst Neftechimicheskogo Sintez
Publication of DK200200624A publication Critical patent/DK200200624A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/28Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22Hormones
    • A61K38/27Growth hormone [GH], i.e. somatotropin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/56Protease inhibitors from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/55Protease inhibitors
    • A61K38/57Protease inhibitors from animals; from humans

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Zoology (AREA)
  • Endocrinology (AREA)
  • Botany (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Description

Patentkrav 1 Polypeptidsammensætning omfattende et polypeptid og en proteolytisk enzymhæmmer, kendetegnet ved, at den yderligere omfatter en organisk syre og et inaktivt excipiens med følgende forhold mellem bestanddelene (vægt-%)Patent claim 1 A polypeptide composition comprising a polypeptide and a proteolytic enzyme inhibitor, characterized in that it further comprises an organic acid and an inactive excipient having the following constituent ratios (wt%)

Polypeptid 1,0*95,0Polypeptide 1.0 * 95.0

Proteolytisk enzymhæmmer 0,02-10,0Proteolytic Enzyme Inhibitor 0.02-10.0

Organisk syre 1,0-94,0Organic acid 1.0-94.0

Inaktivt excipiens 0,2-98,8 (resten) 2 Sammensætning ifølge krav 1,kendetegnet ved, at den omfatter kendte forbindelser, der accelererer absorptionsprocessen, i en mængde, der er 10-50 gange større end mængden af polypeptidetInactive excipient 0.2-98.8 (residue) 2 Composition according to claim 1, characterized in that it comprises known compounds which accelerate the absorption process in an amount 10-1050 times greater than the amount of the polypeptide.

DK200200624A 1999-10-28 2002-04-25 The polypeptide composition DK200200624A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
RU99122655A RU2171687C2 (en) 1999-10-28 Polypeptide composition
PCT/RU2000/000427 WO2001030373A1 (en) 1999-10-28 2000-10-27 Polypeptide composition

Publications (1)

Publication Number Publication Date
DK200200624A true DK200200624A (en) 2002-06-21

Family

ID=20226315

Family Applications (1)

Application Number Title Priority Date Filing Date
DK200200624A DK200200624A (en) 1999-10-28 2002-04-25 The polypeptide composition

Country Status (6)

Country Link
AU (1) AU1316201A (en)
DE (1) DE10085144T1 (en)
DK (1) DK200200624A (en)
IL (1) IL149355A0 (en)
WO (1) WO2001030373A1 (en)
YU (1) YU31902A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201701404D0 (en) 2017-01-27 2017-03-15 Micropharm Ltd Therapies for treating inflammatory disorders

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU225496B1 (en) * 1993-04-07 2007-01-29 Scios Inc Pharmaceutical compositions of prolonged delivery, containing peptides
RU2076733C1 (en) * 1994-03-23 1997-04-10 Институт нефтехимического синтеза им.А.В.Топчеева РАН Method of insulin derivatives preparing
FR2719479B1 (en) * 1994-05-04 1996-07-26 Sanofi Elf Stable lyophilized formulation comprising a protein: assay kit.
US5653987A (en) * 1995-05-16 1997-08-05 Modi; Pankaj Liquid formulations for proteinic pharmaceuticals
US5780431A (en) * 1996-09-20 1998-07-14 Neurobiological Technologies, Inc. Pharmaceutical formulations of corticotropin releasing factor having improved stability in liquid form

Also Published As

Publication number Publication date
WO2001030373A8 (en) 2002-02-07
YU31902A (en) 2004-12-31
IL149355A0 (en) 2002-11-10
WO2001030373A1 (en) 2001-05-03
DE10085144T1 (en) 2003-04-24
AU1316201A (en) 2001-05-08

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment