DK200200624A - The polypeptide composition - Google Patents
The polypeptide composition Download PDFInfo
- Publication number
- DK200200624A DK200200624A DK200200624A DKPA200200624A DK200200624A DK 200200624 A DK200200624 A DK 200200624A DK 200200624 A DK200200624 A DK 200200624A DK PA200200624 A DKPA200200624 A DK PA200200624A DK 200200624 A DK200200624 A DK 200200624A
- Authority
- DK
- Denmark
- Prior art keywords
- polypeptide composition
- polypeptide
- composition
- organic acid
- amount
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title description 5
- 102000004196 processed proteins & peptides Human genes 0.000 title description 5
- 108090000765 processed proteins & peptides Proteins 0.000 title description 5
- VVBXXVAFSPEIJQ-CVIPOMFBSA-N [(2r)-3-[[(2r)-1-[[(2s,5r,8r,11r,12s,15s,18s,21s)-15-[3-(diaminomethylideneamino)propyl]-21-hydroxy-5-[(4-hydroxyphenyl)methyl]-4,11-dimethyl-2-(2-methylpropyl)-3,6,9,13,16,22-hexaoxo-8-propan-2-yl-10-oxa-1,4,7,14,17-pentazabicyclo[16.3.1]docosan-12-yl]am Chemical compound C([C@@H]1C(=O)N[C@@H](C(=O)O[C@H](C)[C@@H](C(N[C@@H](CCCN=C(N)N)C(=O)N[C@H]2CC[C@H](O)N(C2=O)[C@@H](CC(C)C)C(=O)N1C)=O)NC(=O)[C@H](NC(=O)[C@H](O)COS(O)(=O)=O)CC(C)C)C(C)C)C1=CC=C(O)C=C1 VVBXXVAFSPEIJQ-CVIPOMFBSA-N 0.000 description 2
- 150000007524 organic acids Chemical class 0.000 description 2
- 239000000546 pharmaceutical excipient Substances 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/27—Growth hormone [GH], i.e. somatotropin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/56—Protease inhibitors from plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Zoology (AREA)
- Endocrinology (AREA)
- Botany (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Description
Patentkrav 1 Polypeptidsammensætning omfattende et polypeptid og en proteolytisk enzymhæmmer, kendetegnet ved, at den yderligere omfatter en organisk syre og et inaktivt excipiens med følgende forhold mellem bestanddelene (vægt-%)Patent claim 1 A polypeptide composition comprising a polypeptide and a proteolytic enzyme inhibitor, characterized in that it further comprises an organic acid and an inactive excipient having the following constituent ratios (wt%)
Polypeptid 1,0*95,0Polypeptide 1.0 * 95.0
Proteolytisk enzymhæmmer 0,02-10,0Proteolytic Enzyme Inhibitor 0.02-10.0
Organisk syre 1,0-94,0Organic acid 1.0-94.0
Inaktivt excipiens 0,2-98,8 (resten) 2 Sammensætning ifølge krav 1,kendetegnet ved, at den omfatter kendte forbindelser, der accelererer absorptionsprocessen, i en mængde, der er 10-50 gange større end mængden af polypeptidetInactive excipient 0.2-98.8 (residue) 2 Composition according to claim 1, characterized in that it comprises known compounds which accelerate the absorption process in an amount 10-1050 times greater than the amount of the polypeptide.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU99122655A RU2171687C2 (en) | 1999-10-28 | Polypeptide composition | |
PCT/RU2000/000427 WO2001030373A1 (en) | 1999-10-28 | 2000-10-27 | Polypeptide composition |
Publications (1)
Publication Number | Publication Date |
---|---|
DK200200624A true DK200200624A (en) | 2002-06-21 |
Family
ID=20226315
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK200200624A DK200200624A (en) | 1999-10-28 | 2002-04-25 | The polypeptide composition |
Country Status (6)
Country | Link |
---|---|
AU (1) | AU1316201A (en) |
DE (1) | DE10085144T1 (en) |
DK (1) | DK200200624A (en) |
IL (1) | IL149355A0 (en) |
WO (1) | WO2001030373A1 (en) |
YU (1) | YU31902A (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB201701404D0 (en) | 2017-01-27 | 2017-03-15 | Micropharm Ltd | Therapies for treating inflammatory disorders |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
HU225496B1 (en) * | 1993-04-07 | 2007-01-29 | Scios Inc | Pharmaceutical compositions of prolonged delivery, containing peptides |
RU2076733C1 (en) * | 1994-03-23 | 1997-04-10 | Институт нефтехимического синтеза им.А.В.Топчеева РАН | Method of insulin derivatives preparing |
FR2719479B1 (en) * | 1994-05-04 | 1996-07-26 | Sanofi Elf | Stable lyophilized formulation comprising a protein: assay kit. |
US5653987A (en) * | 1995-05-16 | 1997-08-05 | Modi; Pankaj | Liquid formulations for proteinic pharmaceuticals |
US5780431A (en) * | 1996-09-20 | 1998-07-14 | Neurobiological Technologies, Inc. | Pharmaceutical formulations of corticotropin releasing factor having improved stability in liquid form |
-
2000
- 2000-10-27 AU AU13162/01A patent/AU1316201A/en not_active Abandoned
- 2000-10-27 DE DE10085144T patent/DE10085144T1/en not_active Withdrawn
- 2000-10-27 YU YU31902A patent/YU31902A/en unknown
- 2000-10-27 WO PCT/RU2000/000427 patent/WO2001030373A1/en active Application Filing
- 2000-10-27 IL IL14935500A patent/IL149355A0/en unknown
-
2002
- 2002-04-25 DK DK200200624A patent/DK200200624A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2001030373A8 (en) | 2002-02-07 |
YU31902A (en) | 2004-12-31 |
IL149355A0 (en) | 2002-11-10 |
WO2001030373A1 (en) | 2001-05-03 |
DE10085144T1 (en) | 2003-04-24 |
AU1316201A (en) | 2001-05-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |