DK197590A - N-HETEROCYCLIC PROPYLIDENE-1,1-BISPHOSPHONIC ACIDS, THEIR PREPARATION AND A PHARMACEUTICAL PREPARATION - Google Patents

N-HETEROCYCLIC PROPYLIDENE-1,1-BISPHOSPHONIC ACIDS, THEIR PREPARATION AND A PHARMACEUTICAL PREPARATION Download PDF

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Publication number
DK197590A
DK197590A DK197590A DK197590A DK197590A DK 197590 A DK197590 A DK 197590A DK 197590 A DK197590 A DK 197590A DK 197590 A DK197590 A DK 197590A DK 197590 A DK197590 A DK 197590A
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DK
Denmark
Prior art keywords
preparation
propylidene
heterocyclic
bisphosphonic acids
pharmaceutical preparation
Prior art date
Application number
DK197590A
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Danish (da)
Other versions
DK169677B1 (en
DK197590D0 (en
Inventor
Ernst Torndal Binderup
Sven Liisberg
Original Assignee
Leo Pharm Prod Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888808138A external-priority patent/GB8808138D0/en
Application filed by Leo Pharm Prod Ltd filed Critical Leo Pharm Prod Ltd
Priority to DK197590A priority Critical patent/DK169677B1/en
Publication of DK197590A publication Critical patent/DK197590A/en
Publication of DK197590D0 publication Critical patent/DK197590D0/en
Application granted granted Critical
Publication of DK169677B1 publication Critical patent/DK169677B1/en

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Abstract

N-heterocyclic propylidene-1,1-bisphosphonic acids and salts thereof, their preparation, a pharmaceutical preparation The present invention relates to compounds of the formula (I) <IMAGE> in which R1-R8 can be identical or different and denote hydrogen or a straight-chain or branched aliphatic C1-C10 hydrocarbon group. R3 can also, together with either R1 or R5, form a saturated aliphatic 5-, 6- or 7-membered ring which can be substituted by one or more C1-C4-alkyl groups. The compounds of the formula I, which can be used in human and veterinary practice, act on bone metabolism.
DK197590A 1988-04-07 1990-08-20 New n-heterocyclic propylidene-1,1-bis:phosphonic acids - useful as drugs influencing calcium metabolism for treating arthritic disorders, atherosclerosis etc. DK169677B1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK197590A DK169677B1 (en) 1988-04-07 1990-08-20 New n-heterocyclic propylidene-1,1-bis:phosphonic acids - useful as drugs influencing calcium metabolism for treating arthritic disorders, atherosclerosis etc.

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB888808138A GB8808138D0 (en) 1988-04-07 1988-04-07 Chemical compounds
GB8808138 1988-04-07
PCT/DK1989/000071 WO1989009775A1 (en) 1988-04-07 1989-03-29 N-heterocyclic propylidene-1,1-bisphosphonic acids, their production and a pharmaceutical composition
DK8900071 1989-03-29
DK197590A DK169677B1 (en) 1988-04-07 1990-08-20 New n-heterocyclic propylidene-1,1-bis:phosphonic acids - useful as drugs influencing calcium metabolism for treating arthritic disorders, atherosclerosis etc.
DK197590 1990-08-20

Publications (3)

Publication Number Publication Date
DK197590A true DK197590A (en) 1990-08-20
DK197590D0 DK197590D0 (en) 1990-08-20
DK169677B1 DK169677B1 (en) 1995-01-09

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ID=26066245

Family Applications (1)

Application Number Title Priority Date Filing Date
DK197590A DK169677B1 (en) 1988-04-07 1990-08-20 New n-heterocyclic propylidene-1,1-bis:phosphonic acids - useful as drugs influencing calcium metabolism for treating arthritic disorders, atherosclerosis etc.

Country Status (1)

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DK (1) DK169677B1 (en)

Also Published As

Publication number Publication date
DK169677B1 (en) 1995-01-09
DK197590D0 (en) 1990-08-20

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