DK1881956T3 - 3- (2- (dimethylamino) methyl (cyclohex-1-YL)) phenol maleate and its crystal-line form - Google Patents

3- (2- (dimethylamino) methyl (cyclohex-1-YL)) phenol maleate and its crystal-line form

Info

Publication number
DK1881956T3
DK1881956T3 DK06776325T DK06776325T DK1881956T3 DK 1881956 T3 DK1881956 T3 DK 1881956T3 DK 06776325 T DK06776325 T DK 06776325T DK 06776325 T DK06776325 T DK 06776325T DK 1881956 T3 DK1881956 T3 DK 1881956T3
Authority
DK
Denmark
Prior art keywords
cyclohex
dimethylamino
methyl
crystal
line form
Prior art date
Application number
DK06776325T
Other languages
Danish (da)
Inventor
Raumer Markus Von
Martin Szelagiewicz
J Rg Berghausen
Michael Gruss
Wolfgang Hell
Paul Susan Margaret De
Original Assignee
Gr Nenthal Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gr Nenthal Gmbh filed Critical Gr Nenthal Gmbh
Application granted granted Critical
Publication of DK1881956T3 publication Critical patent/DK1881956T3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C215/00Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/46Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C215/64Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13Crystalline forms, e.g. polymorphs
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
DK06776325T 2005-07-22 2006-07-20 3- (2- (dimethylamino) methyl (cyclohex-1-YL)) phenol maleate and its crystal-line form DK1881956T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102005034974A DE102005034974A1 (en) 2005-07-22 2005-07-22 Salt of dimethylaminomethyl-phenyl-cyclohexane and its crystalline forms
PCT/EP2006/007160 WO2007009792A1 (en) 2005-07-22 2006-07-20 3-(2-(dimethylamino)methyl(cyclohex-1-yl))phenol maleate and its crystalline forms

Publications (1)

Publication Number Publication Date
DK1881956T3 true DK1881956T3 (en) 2009-09-07

Family

ID=37084866

Family Applications (1)

Application Number Title Priority Date Filing Date
DK06776325T DK1881956T3 (en) 2005-07-22 2006-07-20 3- (2- (dimethylamino) methyl (cyclohex-1-YL)) phenol maleate and its crystal-line form

Country Status (26)

Country Link
EP (1) EP1881956B1 (en)
JP (1) JP5205259B2 (en)
KR (1) KR20080033436A (en)
CN (1) CN101228110A (en)
AR (1) AR057674A1 (en)
AT (1) ATE431332T1 (en)
AU (1) AU2006271856B2 (en)
BR (1) BRPI0614057A2 (en)
CA (1) CA2615926A1 (en)
CY (1) CY1109208T1 (en)
DE (2) DE102005034974A1 (en)
DK (1) DK1881956T3 (en)
EC (1) ECSP088088A (en)
ES (1) ES2326493T3 (en)
HK (1) HK1112612A1 (en)
HR (1) HRP20090412T1 (en)
IL (1) IL188897A (en)
MX (1) MX2008000743A (en)
NO (1) NO20080826L (en)
PE (1) PE20070368A1 (en)
PL (1) PL1881956T3 (en)
PT (1) PT1881956E (en)
RU (1) RU2434845C2 (en)
SI (1) SI1881956T1 (en)
WO (1) WO2007009792A1 (en)
ZA (1) ZA200801703B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI384986B (en) * 2007-01-17 2013-02-11 Lg Life Sciences Ltd Maleic acid monosalt of antiviral agent and pharmaceutical composition containing the same
CN104447360B (en) * 2007-12-07 2017-04-12 格吕伦塔尔有限公司 Crystalline modifications of (1r, 2r)-3-(3-dimethylamino-1-ethyl-2-methyl -propyl)-phenol
EP2085081A1 (en) 2008-02-04 2009-08-05 Grünenthal GmbH 3-(2-dimethyl amino methyl-cyclohexyl) phenol for treating polyneuropathic pain

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19525137C2 (en) * 1995-07-11 2003-02-27 Gruenenthal Gmbh 6-Dimethylaminomethyl-1-phenyl-cyclohexane compounds as intermediates for the preparation of pharmaceutical agents
DE10218862A1 (en) * 2002-04-26 2003-11-06 Gruenenthal Gmbh Process for the chlorination of tertiary alcohols
DE10356362A1 (en) * 2003-11-28 2005-06-23 Grünenthal GmbH Use of 1-phenyl-3-dimethylamino-propane compounds for the treatment of anxiety disorders

Also Published As

Publication number Publication date
ECSP088088A (en) 2008-02-20
EP1881956A1 (en) 2008-01-30
IL188897A0 (en) 2008-04-13
WO2007009792A1 (en) 2007-01-25
AU2006271856B2 (en) 2012-03-01
IL188897A (en) 2012-12-31
HRP20090412T1 (en) 2009-09-30
CY1109208T1 (en) 2014-07-02
PE20070368A1 (en) 2007-05-12
AU2006271856A1 (en) 2007-01-25
ATE431332T1 (en) 2009-05-15
MX2008000743A (en) 2008-03-10
RU2008106455A (en) 2009-08-27
CN101228110A (en) 2008-07-23
SI1881956T1 (en) 2009-10-31
RU2434845C2 (en) 2011-11-27
KR20080033436A (en) 2008-04-16
JP2009502757A (en) 2009-01-29
PT1881956E (en) 2009-06-26
CA2615926A1 (en) 2007-01-25
DE502006003728D1 (en) 2009-06-25
PL1881956T3 (en) 2009-10-30
AR057674A1 (en) 2007-12-12
JP5205259B2 (en) 2013-06-05
NO20080826L (en) 2008-02-20
ES2326493T3 (en) 2009-10-13
BRPI0614057A2 (en) 2012-12-11
EP1881956B1 (en) 2009-05-13
DE102005034974A1 (en) 2007-04-19
HK1112612A1 (en) 2008-09-12
ZA200801703B (en) 2009-08-26

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