DK170604B1 - Metering unit for metering measured-off quantities of a liquid - Google Patents
Metering unit for metering measured-off quantities of a liquid Download PDFInfo
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- DK170604B1 DK170604B1 DK136593A DK136593A DK170604B1 DK 170604 B1 DK170604 B1 DK 170604B1 DK 136593 A DK136593 A DK 136593A DK 136593 A DK136593 A DK 136593A DK 170604 B1 DK170604 B1 DK 170604B1
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- piston rod
- housing
- pins
- liquid
- metering
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
- A61M5/5013—Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
- A61M5/5013—Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe
- A61M5/502—Means for blocking the piston or the fluid passageway to prevent illegal refilling of a syringe for blocking the piston
Landscapes
- Health & Medical Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
Description
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DK 170604 BTDK 170604 BT
Opfindelsen angår en doseringsenhed til dosering af afmålte mængder af en væske, hvilken doseringsenhed omfatter et cylindrisk hus af plast til optagelse af den pågældende væske, som fortrinsvis findes i en separat beholder, hvilket hus har ved 5 den distale ende midler til fastgørelse af en væskeudstrømningskanyle, og hvilken doseringsenhed har en stempelstang til påvirkning af et stempel til uddrivning af væsken, idet der imellem huset og stempelstangen findes styremidler, som er tildannet ud i ét med huset, og som tillader forskydning af 10 stempelstangen i retning imod husets distale ende og forhindrer forskydning i den modsatte retning, og hvor stempelstangen omfatter en kropsdel med aksialt forløbende, i hovedsagen parallelle sideflader.BACKGROUND OF THE INVENTION 1. Field of the Invention This invention relates to a metering unit for measuring metered quantities of a liquid, the metering unit comprising a cylindrical plastic housing for receiving said fluid, which is preferably contained in a separate container, which housing has at the distal end means for attaching a liquid outflow cannula and which metering unit has a piston rod for actuating a piston for expelling the liquid, there being between the housing and the piston rod guiding means formed integrally with the housing, which permits displacement of the piston rod towards the distal end of the housing and prevents displacement in the opposite direction, and wherein the piston rod comprises a body portion with axially extending, generally parallel side faces.
Der findes forskellige doseringsenheder af den indledningsvis 15 nævnte type, hvor stempelstangen er tilknyttet indstillingsindretninger, som muliggør, at brugeren på forhånd kan indstille doseringsenheden til afgivelse af en bestemt væskemængde ved efterfølgende aktivering af stempelstangen. Stempelstangen forskydes under aktiveringen fremad i retning imod 20 husets distale ende, idet forskydning i den modsatte retning er forhindret som følge af, at der imellem huset og stemplet findes en skraldemekanisme. Det har vist sig, at en sådan skraldemekanisme er vanskelig at fremstille på grund af, at de indgribende dele skal fremstilles med meget små dimen-25 sionstolerancer. Samtidigt hermed indebærer brugen af en skraldemekanisme, at der er en nedre grænse for den nøjagtighed, hvormed de afmålte mængder af væske kan indstilles og afgives. Ved brug af eksisterende doseringsenheder til dosering af afmålte mængder af insulin indebærer skraldemekanis-30 men, at de afmålte mængder adskiller sig ved spring på to enheder.There are various dosing units of the type mentioned initially where the piston rod is associated with adjusting devices which allow the user to pre-set the dosing unit to deliver a certain amount of liquid upon subsequent activation of the piston rod. During actuation, the piston rod is displaced forwards towards the distal end of the housing, displacement in the opposite direction is prevented as a ratchet mechanism exists between the housing and the piston. It has been found that such a rubbing mechanism is difficult to manufacture due to the fact that the engaging parts must be manufactured with very small dimensional tolerances. At the same time, the use of a ratchet mechanism implies that there is a lower limit to the accuracy with which the measured quantities of liquid can be set and dispensed. When using existing dosing units for dosing measured amounts of insulin, the garbage mechanism implies that the measured amounts differ by jumps on two units.
Sådanne doseringsenheder kendes f.eks. fra EP Bl nr. 327.910.Such dosage units are known e.g. from EP Bl No. 327,910.
Fra WO Al 92/12747 kendes en lignende doseringsindretning.From WO Al 92/12747 a similar dosing device is known.
Denne muliggør trinløs indstilling og afgivelse af afmålte 2 DK 170604 B1 mængder af insulin ved brug af en separat ringformet metal-ring, som er placeret omkring en glatvægget stempelstang, og som har radialt indadragende flige, som virker som modhager over for stempelstangen. Denne indretning er både kompliceret v 5 at samle og vanskelig at bortskaffe efter brug, hvis der skal tages specielt hensyn til, at ringen med modhager er af metal * og den øvrige del af indretningen er af plast.This enables stepless adjustment and delivery of metered amounts of insulin using a separate annular metal ring which is positioned around a smooth-walled piston rod and having radially inwardly projecting tabs which act as barbs against the piston rod. This device is both complicated to assemble and difficult to dispose of after use if special consideration is given to the fact that the ring with barbs is metal * and the other part of the device is plastic.
Doseringsenheden ifølge opfindelsen er ejendommelig ved, at huset har en til optagelse af nævnte kropsdel indrettet passa-10 gedel, som af grænses af en i hovedsagen plan sideflade, som er indrettet til at ligge an imod den ene af nævnte kropsdels parallelle sideflader, og mindst to eftergivelige tappe, som er placeret efter hinanden, set i stempelstangens fremførings-retning, og som i afslappet tilstand strækker sig i alt væ-15 sentligt vinkelret ind imod passagedelens plane sideflade fra en modsat beliggende side, idet hver taps frie ende befinder sig i en afstand herfra, som er mindre end nævnte kropsdels tykkelse, og idet hver taps frie ende er bueformet afrundet.The dosing unit according to the invention is characterized in that the housing has a passage part arranged for receiving said body part, which is bounded by a generally planar side surface arranged to abut one of the parallel side surfaces of one of said body part, and at least two resilient pins, positioned one after the other, viewed in the direction of advance of the piston rod, and which, in the relaxed state, extend substantially perpendicularly to the plane side surface of the passage portion from an opposite side, the free end of each pin being in the a distance therefrom which is less than the thickness of said body portion and the free end of each taper is rounded.
Herved opnås, at der tilvejebringes en doseringsenhed, som er 20 forholdsvis let at fremstille og skaffe af vejen efter brug, og hvor stempelstangen kan forskydes trinløst og især åbner mulighed for stabil uddrivning af afmålte mængder af en hvilken som helst størrelse uden nogen mængdemæssige spring. Dette skyldes, at stempelstangens bevægelse i fremadgående retning 25 imod den distale ende foregår let og trinløst ved, at kropsdelens ene side glider solidt understøttet an imod passagedelens plane sideflade, medens den anden side skubber tappene til side. Stempelstangen hindres på stabil og sikker måde i at blive trukket tilbage igen ved at tappene virker som kiler i 30 en hvilken som helst stilling som følge af at de ved forsøg på » at trække stempelstangen tilbage øjeblikkeligt klemmer dennes nævnte kropsdel fast og urokkeligt an imod passagedelens plane sideflade. De pågældende samvirkende dele lader sig fremstille uden større krav til dimensionstolerancernes finhed, især på 35 grund af, at tappene er bueformet afrundet ved deres frie 3 DK 170604 B1 ender. Dette medfører nemlig at forsøg på, at trække stempelstangen bagud indebærer, at tappene påvirker siden af stempelstangen med en progressivt voksende radius som følge af afrulningen hen over den bueformede flade. Tappene fastlåser herved 5 også stempelstangen med en progressivt voksende kraft. På grund af, at stempelstangen til enhver tid er i glidende indgreb med henholdsvis den plane flade og tappene, bliver bevægelsen af stempelstangen fuldstændig støjfri. Efter endt brug kan doseringsenheden let skaffes af vejen, da den udelukkende 10 er fremstillet af plast. Tilstedeværelsen af mindst to tappe bidrager til at understøtte stempelstangen i en i hovedsagen retlinet aksialt forløbende bevægelsesbane.This provides a metering unit which is relatively easy to manufacture and obtain from the road after use, and in which the piston rod can be shifted steplessly, and in particular allows for stable expulsion of measured quantities of any size without any quantitative leaps. This is because the movement of the piston rod in the forward direction 25 towards the distal end takes place easily and steplessly by the one side of the body member sliding firmly supported against the flat side surface of the passage part while the other side pushes the pins aside. The piston rod is in a stable and secure manner prevented from being retracted again by the pins acting as wedges in any position as a result of their attempting to immediately retract the said piston rod firmly and unwaveringly against the passage portion of the piston rod. flat side surface. The cooperating parts in question can be manufactured without great demands on the finesse of the dimension tolerances, especially because the pins are rounded at their free ends. This means that attempting to pull the piston rod backwards means that the pins affect the side of the piston rod with a progressively increasing radius as a result of rolling over the arcuate surface. The pins hereby also lock the piston rod with a progressively increasing force. Because the piston rod is at all times in sliding engagement with the planar surface and the pins respectively, the movement of the piston rod becomes completely silent. After use, the dosing unit can easily be disposed of by the way, since it is made entirely of plastic. The presence of at least two pins helps to support the piston rod in a generally rectilinear axially extending path of movement.
Desuden kan ifølge opfindelsen tappene være tildannet ud i ét med huset, idet der ved overgangen imellem hver tap og huset 15 er en hængseldannende tykkelsesreduktion, så at den nødvendige eftergivelighed opnås på enklest mulig måde, samtidig med at tappene i sig selv sikres en passende stivhed til at kunne udøve den ønskede kilevirkning.In addition, according to the invention, the pins may be formed integrally with the housing, with at the transition between each pin and the housing 15 a hinge-forming thickness reduction, so that the necessary resilience is achieved in the simplest possible way, while at the same time ensuring the pins themselves an appropriate stiffness. to be able to exert the desired wedge effect.
Doseringsenheden er ifølge opfindelsen også ejendommelig ved, 20 at tappene er i hovedsagen plane dele med ophøjede kanter langs deres frie ender, så at det overfladeområde på tappene, der samvirker med stempelstangen bliver forholdsvis stort.The dosing unit according to the invention is also characterized in that the pins are generally flat parts with raised edges along their free ends, so that the surface area of the pins cooperating with the piston rod becomes relatively large.
Endelig kan ifølge opfindelsen hensigtsmæssigt en eller flere af de samvirkende flader være tildannet med en ru overflade.Finally, according to the invention, one or more of the interacting surfaces may conveniently be formed with a rough surface.
25 Opfindelsen forklares nærmere nedenfor under henvisning til tegningen, hvor fig. 1 viser en doseringsenhed, set i langsgående tværsnit, fig. 2 den nærmest stempelstangen værende ende af doseringsenhedens hus, set i større målforhold og i aksialt snit, adskilt \ 30 fra den øvrige del af enheden uden stempelstangen, 4 DK 170604 B1 fig. 3 samme som fig. 2, men med en del af en stempelstang, vist i indgreb med huset på det pågældende sted, og fig. 4 huset med stempelstangen, set i snit efter linien I-I i ¥ fig. 3 med dele for tydeligheds skyld fjernet.The invention is explained in more detail below with reference to the drawing, in which fig. 1 is a longitudinal sectional view of a metering unit; FIG. 2 shows the end of the dosing rod closest to the housing of the metering unit, seen in larger dimensions and in axial section, separated \ 30 from the other part of the unit without the piston rod, 4 DK 170604 B1 fig. 3 the same as FIG. 2 but with a portion of a piston rod shown in engagement with the housing at that location; and FIG. 4 shows the housing with the piston rod, cut in section along line I-I in ¥ fig. 3 with parts removed for clarity.
5 Den i fig. 1 viste doseringsenhed svarer i store træk til den, der er kendt fra EP-patentskrift nr. 0 327 910. Den omfatter et hus 1 til optagelse af en tubule 2 af glas, hvori der befinder sig en væske 3, såsom insulin. Glastubulen 2 har et stempel 4 til uddrivning af væsken 3 via en igennem den mod-10 satte ende stukket kanyle 5, som er fastgjort til huset 1 på almindelig kendt måde ved påskruning af en kapselformet hætte 6. Glastubulen 2 fastholdes i huset ved hjælp af en lukkehætte 7, som kan være fastgjort til huset ved snapvirkning. Lukkehætten 7 er indrettet til gennemstikning af en udragende 15 ende af kanylen 5, som kan nå ind i det indre af glastubulen 2. Denne gennemtrængning og indføring af kanylen 5 sker hensigtsmæssigt under påskruning af den kanylebærende hætte 6 på husets 1 lukkehætte 7.5 The embodiment of FIG. The dosage unit shown in Figure 1 broadly corresponds to that known from EP-A-0 327 910. It comprises a housing 1 for receiving a glass tubule 2 in which is contained a liquid 3, such as insulin. The glass tube 2 has a piston 4 for expelling the liquid 3 via a cannula 5 inserted through the opposite end, which is attached to the housing 1 in a generally known manner by screwing on a capsule-shaped cap 6. The glass tube 2 is held in the housing by means of a closure cap 7 which may be attached to the housing by snap action. The closure cap 7 is arranged to pierce a protruding end of the cannula 5 which can reach the interior of the glass tube 2. This penetration and insertion of the cannula 5 is conveniently done by screwing the cannula-bearing cap 6 onto the closure cap 7 of the housing 1.
Ved den modsat kanylen 5 værende ende har doseringsenheden en 20 stempelstang 8 til drivning af stemplet 4 i glastubulen 2.At the opposite end of the cannula 5, the metering unit has a piston rod 8 for driving the piston 4 in the glass tube 2.
Denne stempelstang 8, hvis tværsnit fremgår af fig. 4, har to modsat placerede langsgående riller 9, 10, hvorved stem pelstangen 8 har en central placeret langsgående kropsdel 11, som af grænses af to parallelle sideflader 12, 13. Den ene 25 sideflade 13 er som det tydeligere fremgår af fig. 2 og 3 indrettet til at samvirke med en på huset 1 tildannet plan flade 14, medens den anden sideflade 12 er indrettet til at samvirke med på huset tildannede kiledannende tappe 15 og 16.This piston rod 8, whose cross section is shown in FIG. 4, has two oppositely positioned longitudinal grooves 9, 10, whereby the stem pile rod 8 has a centrally located longitudinal body portion 11, which is bounded by two parallel side faces 12, 13. The one side face 13 is more clearly seen in FIG. 2 and 3 arranged to cooperate with a plane surface 14 formed on the housing 1, while the second side surface 12 is arranged to cooperate with wedge-forming pins 15 and 16 formed on the housing.
Husets plane falde 14 og tappe 15 og 16 befinder sig over for ; 30 hinanden på hver sin side af en passage 17, som er tildannet ved den længst væk fra kanylen beliggende ende af huset 1.The plane of the house falls 14 and pins 15 and 16 are facing; 30 on each side of a passage 17 formed at the furthest away from the cannula end of the housing 1.
tt
Denne passage 17 har en til stempel stangen 8 svarende tværsnitsform, idet den ved indgangssiden til huset har en tragtformet del 18 ud for kropsdelen.This passage 17 has a cross-sectional shape corresponding to the piston rod 8, having at the entrance side of the housing a funnel-shaped portion 18 next to the body portion.
5 DK 170604 B15 DK 170604 B1
Den plane side 14 og de modsat placerede tappe 15 og 16 befinder sig et kort stykke inden for passagens 17 munding på hver sin side af den del 19 af passagen 17, som er indrettet til optagelse af stemplets 8 kropsdel 11. Den plane flade 14 er 5 tilvejebragt ved hjælp af en indadragende flig 20, som støttes af tværgående vægge 21 og 22, der er tildannet ud i ét med husets 1 udvendige væg 23. Tappene 15 og 16 er tildannet ud i ét med den diamentralt modsatte side af husets 1 udvendige væg 23, idet de strækker sig i hovedsagen vinkelret ind imod den 10 plane flade 14.The flat side 14 and the opposite pins 15 and 16 are located a short distance within the mouth of the passage 17 on either side of the portion 19 of the passage 17 which is arranged to receive the body portion 11. of the piston 8. 5 provided by an inwardly extending tab 20 supported by transverse walls 21 and 22 formed integrally with the outer wall of the housing 1. The pins 15 and 16 are formed integrally with the diametrically opposite side of the exterior of the housing 1. wall 23, extending substantially perpendicular to the planar surface 14.
Tappene 15 og 16 har et i hovedsagen rektangulært tværsnit med en ophøjet indvendig kant henholdsvis 24 og 25. Den over imod den plane flade 14 vendende side på tappene er bueformet tildannet, idet tappenes frie bueformede endeflader udgør dele af 15 en cylinderflade, der er parallelt forløbende med den plane flade 14. Tappene 15 og 16 er således dimensioneret, at afstanden imellem deres frie ender og den modsat placerede plane flade 14 er mindre end tykkelsen af stemplets 8 kropsdel 11. Når stemplet 8 er anbragt på plads i huset 1, vil det derfor 20 have skubbet tappene 15 og 16 lidt indad imod husets indre, således som vist i fig. 3.The pins 15 and 16 have a generally rectangular cross-section with a raised inner edge 24 and 25. The face facing the flat surface 14, respectively, is arcuate, the free arcuate end faces of the pins forming portions of 15 a cylinder surface which is parallel. extending with the flat surface 14. The pins 15 and 16 are dimensioned such that the distance between their free ends and the opposite flat surface 14 is less than the thickness of the body portion 11. of the piston 8 When the piston 8 is placed in place in the housing 1, it therefore 20 has pushed the pins 15 and 16 slightly inwards towards the interior of the housing, as shown in FIG. Third
Stempelstangen 8 kan herved let forskydes fremad mod doseringsenhedens kanylebærende, distale ende (nedad i forhold til fig. 3) , medens forsøg på at bevæge stemplet tilbage i den 25 modsatte retning, forhindres ved at tappene på kileagtig måde låser stempelstangen 8 fast imod den plane flade 14. Denne fastlåsning kan ske i en hvilken som helst stilling af stemplet 8 i forhold til huset.The piston rod 8 can hereby be easily moved forward towards the cannula-bearing distal end of the metering unit (downwardly in relation to Fig. 3), while attempts to move the piston back in the opposite direction are prevented by the pins in a wedge-like manner locking the piston rod 8 firmly against the plane. surface 14. This locking can occur at any position of the piston 8 relative to the housing.
Som det fremgår af fig. 2 og 3 findes der en åbning 26 i hu-30 sets væg. Denne åbning befinder sig ud for tappene 15 og 16 og de dele, der danner den plane flade 14 for at lette støbningen af huset, der er fremstillet af et passende fortrinsvis gennemsigtigt plastmateriale.As shown in FIG. 2 and 3 there is an opening 26 in the wall of the set of 30. This opening is adjacent to the pins 15 and 16 and the parts forming the flat surface 14 to facilitate the molding of the housing made of a suitable preferably transparent plastic material.
DK 170604 B1 sDK 170604 B1 p
Som det fremgår, er tappene 15 og 16 eftergivelige, så at stempelstangen 8 let kan føres fremad i forhold til huset 1.As can be seen, the pins 15 and 16 are compliant, so that the piston rod 8 can be easily moved forward with respect to the housing 1.
Denne eftergivelighed er passende opnået ved at lade tappene 15 og 16 være forbundet med husets 1 udvendige væg via tykkel-5 sesreduktioner 27 og 28 i umiddelbar nærhed af husets 1 udvendige væg 23.This resilience is conveniently achieved by letting pins 15 and 16 connect to the exterior wall of the housing 1 via thickness reductions 27 and 28 in the immediate vicinity of the outer wall 23 of the housing 1.
i'in'
Som det fremgår af fig. 1 og 4, har stempelstangen 8 dele af et langs dets udvendige periferi tildannet gevind 30, hvorpå der er påskruet et møtrikorgan 31. Dette møtrikorgan 31 har 10 udvendigt radialt udragende fremspring 32 og 33, som strækker sig aksialt langs møtrikorganets 31 udvendige side, og som optages i tilsvarende riller henholdsvis 38 og 39 i en omkringliggende muffeformet indstillingsindretning 40. Denne indstillingsindretning 40 har ved den nærmest huset 1 værende 15 ende indvendigt en rundtgående rille, hvori der er optaget et rundtgående fremspring på huset, så at der åbnes mulighed for drejning af indstillingsindretningen 40 samtidig med, at den fastholdes over for aksial forskydning i forhold til huset. Møtrikorganet 31 er tildannet ud i ét med et rørformet indi-20 katororgan 41, som strækker sig koaksialt med stempelstangen 8 i retning væk fra huset 1 imellem stempelstangen 8 og indstillingsindretningen 18. Ved dets frie uden for indstillingsindretningen 40 ragende ende har indikatororganet 41 en endeknop 42, som er tildannet med i hovedsagen samme udvendige 25 diameter som indstillingsindretningen 18.As shown in FIG. 1 and 4, the piston rod 8 has parts of a thread 30 formed along its outer periphery, on which is screwed a nut member 31. This nut member 31 has externally radially projecting projections 32 and 33 extending axially along the outer side of the nut member 31, and which is accommodated in corresponding grooves 38 and 39, respectively, in a surrounding sleeve-shaped adjusting device 40. This adjusting device 40 has at the end of the housing 1 at the end 15 an inner groove, in which a circumferential projection is accommodated on the housing, thus allowing for rotation. of the adjusting device 40 while retaining axial displacement relative to the housing. The nut member 31 is formed integrally with a tubular indicator member 41 extending coaxially with the piston rod 8 in a direction away from the housing 1 between the piston rod 8 and the adjusting device 18. At its free end extending beyond the adjusting device 40, the indicator means 41 has an end knob. 42 which is formed with substantially the same outside diameter 25 as the adjusting device 18.
Doseringsindretningen har endvidere en aftagelig hætte 43 til beskyttelse af kanylen 5, når doseringsenheden ikke er i brug.The dosing device further has a removable cap 43 for protecting the cannula 5 when the dosing unit is not in use.
Doseringsenheden fungerer på følgende måde. Indstil-3 0 lings indretningen 40 drejes rundt i forhold til huset 1 og den ς herpå fastsiddende hætte 43. Herved møtrikorganet 31 drives med rundt, idet møtriksorganets 31 mulighed for at ligge an imod enden af huset 1, hindrer en drejning af indstillingsindretningen i den forkerte retning. Møtrikorganets 31 35 rotation i forhold til stempelstangen 8 medfører, at det som 7 DK 170604 B1 følge af gevindet 30 drives i retning væk fra glastubulen 2, hvorved indikatororganet 41 bevæger sig aksialt ud fra indstillingsindretningens 40 frie ende. Herved blotlægges en måleskala på indikatororganets 41 udvendige side. Denne skala 5 kan være således opdelt, at man kan aflæse den pågældende doseringsmængde for hver fulde omdrejning af indstillingsindretningen i forhold til hætten 43, medens en ikke-vist skala på den nærmest hætten 43 værende ende af indstillingsindretningen 40 angiver indstillingsmængden ved dele af 10 en hel omdrejning af indstillingsindretningen 40 i forhold til hætten 43.The dosing unit works as follows. The adjusting device 40 is rotated relative to the housing 1 and the cap 43 attached thereto. The nut 31 is thereby driven around, the ability of the nut 31 to abut against the end of the housing 1 preventing a rotation of the adjusting device in the housing. wrong direction. The rotation of the nut 31 with respect to the piston rod 8 causes it, as a result of the thread 30, to be driven in a direction away from the glass tube 2, whereby the indicator member 41 moves axially from the free end of the adjusting device 40. This exposes a measurement scale on the outside of the indicator means 41. This scale 5 may be so divided that one can read the respective dosage amount for each full rotation of the adjusting device relative to the cap 43, while a non-displayed scale on the end of the adjusting device 40 indicating the setting quantity at portions of 10 full rotation of the adjusting device 40 relative to the cap 43.
Når den ønskede doseringsmængde er indstillet, standses indstillingsindretningens 40 drejning. Derefter fjernes hætten 43, og doseringsenheden anbringes på det ønskede sted ved 15 indstikning af kanylen 5. Dernæst presses indikatororganet 41 tilbage ind i indstillingsindretningen 40 ved anpresning af endeknoppen 42, indtil denne bevægelse standses som følge af møtrikorganets 31 anslag imod enden af huset 1. Forskydningen af indikatororganet 41 og det hermed forbundne møtrikorgan 31 20 medfører, at stempelstangen 8 forskydes et tilsvarende stykke og derved presser glastubulens 2 stempel 4 frem imod væskens 3 udstrømningsende. Herved presses der en mængde af væske ud af glastubulen, svarende til den på måleskalaerne afmålte mængde. Når injektionen af væske er tilendebragt har doseringsenheden 25 samme længde som før indstillingen.When the desired amount of dosing is set, the rotation of the adjusting device 40 is stopped. Then the cap 43 is removed and the metering unit is placed at the desired location by inserting the cannula 5. Next, the indicator means 41 is pushed back into the setting device 40 by pressing the end knob 42 until this movement is stopped as a result of the impact of the nut 31 against the end of the housing 1. The displacement of the indicator member 41 and the associated nut member 31 20 causes the piston rod 8 to be displaced a corresponding piece, thereby pushing the piston 4 of the glass tube 2 towards the outlet end of the liquid 3. Hereby, a quantity of liquid is squeezed out of the glass tube, corresponding to the amount measured on the measuring scales. When the injection of liquid is completed, the metering unit 25 is the same length as before the setting.
Under indstillingen fastholdes stempelstangen 8 imod tilbagetrækning ved hjælp af tappene 15 og 16 og den her over for beliggende plane flade 14 i huset 1. Under anpresningen af endeknoppen 42 og dermed udpresningen af væsken 3 fra kanylen 30 5 bevæges stempelstangen 8 let fremad ved tilbageskubning af tappene 15 og 16. På grund af at tappene 15 og 16 og den plane flade 14 samt stempelstangens kropsdel 11 indgriber med hinanden langs flader, kan stempelstangen standses i en hvilken som helst stilling, så at der kan udpresses en hvilken som helst 35 ønsket dosis af væsken 3 uden nogen trinvis variation heraf.During the adjustment, the piston rod 8 is held against retraction by means of the pins 15 and 16 and the plane face 14 located therein in the housing 1. During the pressing of the end bud 42 and thus the pressing of the liquid 3 from the cannula 30 5, the piston rod 8 is easily moved forward by pushing back the pins 15 and 16. Because pins 15 and 16 and the flat surface 14 and the body part 11 of the piston rod engage with each other along surfaces, the piston rod can be stopped in any position so that any desired dose can be squeezed out. of the liquid 3 without any stepwise variation thereof.
Claims (4)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK136593A DK170604B1 (en) | 1993-12-07 | 1993-12-07 | Metering unit for metering measured-off quantities of a liquid |
| PCT/DK1995/000220 WO1996039214A1 (en) | 1993-12-07 | 1995-06-06 | A dosage unit for dosing measured amounts of a fluid |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DK136593 | 1993-12-07 | ||
| DK136593A DK170604B1 (en) | 1993-12-07 | 1993-12-07 | Metering unit for metering measured-off quantities of a liquid |
| PCT/DK1995/000220 WO1996039214A1 (en) | 1993-12-07 | 1995-06-06 | A dosage unit for dosing measured amounts of a fluid |
| DK9500220 | 1995-06-06 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| DK136593D0 DK136593D0 (en) | 1993-12-07 |
| DK136593A DK136593A (en) | 1995-06-08 |
| DK170604B1 true DK170604B1 (en) | 1995-11-13 |
Family
ID=26065656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK136593A DK170604B1 (en) | 1993-12-07 | 1993-12-07 | Metering unit for metering measured-off quantities of a liquid |
Country Status (2)
| Country | Link |
|---|---|
| DK (1) | DK170604B1 (en) |
| WO (1) | WO1996039214A1 (en) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6716198B2 (en) | 2000-05-18 | 2004-04-06 | Novo Nordisk A/S | Injection device |
| DE102005037962A1 (en) | 2005-08-11 | 2007-02-15 | Arzneimittel Gmbh Apotheker Vetter & Co. Ravensburg | syringe |
| EP2201972A1 (en) * | 2008-12-23 | 2010-06-30 | Sanofi-Aventis Deutschland GmbH | Fixed dose injection device with resettable drive mechanism |
| US9463283B2 (en) | 2009-06-01 | 2016-10-11 | Sanofi-Aventis Deutschland Gmbh | Dosing mechanism for a drug deliver device |
| US9199040B2 (en) | 2009-06-01 | 2015-12-01 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device last dose lock-out mechanism |
| US10034982B2 (en) | 2009-06-01 | 2018-07-31 | Sanofi-Aventis Deutschland Gmbh | Spindle for a drug delivery device |
| US8728043B2 (en) | 2009-06-01 | 2014-05-20 | Sanofi-Aventis Deutschland Gmbh | Drive mechanism for a drug delivery device |
| US8672896B2 (en) | 2009-06-01 | 2014-03-18 | Sanofi-Aventis Deutschland Gmbh | Inner housing for a drug delivery device |
| US8585656B2 (en) | 2009-06-01 | 2013-11-19 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism for priming a drug delivery device |
| US8974423B2 (en) | 2009-06-01 | 2015-03-10 | Sanofi-Aventis Deutschland Gmbh | Resettable drug delivery device |
| US9108007B2 (en) * | 2009-06-01 | 2015-08-18 | Sanofi-Aventis Deutschland Gmbh | Spindle and bearing combination and drug delivery device |
| US9238106B2 (en) | 2009-06-01 | 2016-01-19 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism for priming a drug delivery device |
| US9623187B2 (en) | 2009-06-01 | 2017-04-18 | Sanofi-Aventis Deutschland Gmbh | Resettable drug delivery device |
| US9457150B2 (en) | 2009-06-01 | 2016-10-04 | Sanofi-Aventis Deutschland Gmbh | Biasing mechanism for a drug delivery device |
| US8257319B2 (en) | 2009-06-01 | 2012-09-04 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device inner housing having helical spline |
| US9345840B2 (en) | 2009-06-01 | 2016-05-24 | Sanofi-Aventis Deutschland Gmbh | Drug delivery dose setting mechanism with variable maximum dose |
| US9950116B2 (en) | 2009-06-01 | 2018-04-24 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism for priming a drug delivery device |
| US9125994B2 (en) | 2009-06-01 | 2015-09-08 | Sanofi—Aventis Deutschland GmbH | Drug delivery device with dose dial sleeve rotational stop |
| CN104436375A (en) * | 2014-12-30 | 2015-03-25 | 江苏华阳电器有限公司 | Injection pen |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK166948B1 (en) * | 1988-02-10 | 1993-08-09 | Dcp Af 1988 As | DOSING UNIT FOR DOSING A NUMBER OF MEASURED QUANTITIES OF A FLUID, SUCH AS INSULIN, FROM A GLASS STUBLE |
-
1993
- 1993-12-07 DK DK136593A patent/DK170604B1/en not_active IP Right Cessation
-
1995
- 1995-06-06 WO PCT/DK1995/000220 patent/WO1996039214A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO1996039214A1 (en) | 1996-12-12 |
| DK136593D0 (en) | 1993-12-07 |
| DK136593A (en) | 1995-06-08 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| B1 | Patent granted (law 1993) | ||
| PBP | Patent lapsed |