DK166235B - DEVICE FOR WETTING TEST STRIPS WITH MULTIPLE TEST AREAS - Google Patents
DEVICE FOR WETTING TEST STRIPS WITH MULTIPLE TEST AREAS Download PDFInfo
- Publication number
- DK166235B DK166235B DK395887A DK395887A DK166235B DK 166235 B DK166235 B DK 166235B DK 395887 A DK395887 A DK 395887A DK 395887 A DK395887 A DK 395887A DK 166235 B DK166235 B DK 166235B
- Authority
- DK
- Denmark
- Prior art keywords
- test
- areas
- test strips
- wetting
- strips
- Prior art date
Links
- 238000012360 testing method Methods 0.000 title claims abstract description 40
- 239000007788 liquid Substances 0.000 claims description 6
- 238000009736 wetting Methods 0.000 claims description 5
- 230000008021 deposition Effects 0.000 claims description 3
- 238000005507 spraying Methods 0.000 abstract description 4
- 239000003153 chemical reaction reagent Substances 0.000 description 5
- 210000002700 urine Anatomy 0.000 description 3
- BPYKTIZUTYGOLE-IFADSCNNSA-N Bilirubin Chemical compound N1C(=O)C(C)=C(C=C)\C1=C\C1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(\C=C/3C(=C(C=C)C(=O)N\3)C)N2)CCC(O)=O)N1 BPYKTIZUTYGOLE-IFADSCNNSA-N 0.000 description 2
- 239000006199 nebulizer Substances 0.000 description 2
- OBHRVMZSZIDDEK-UHFFFAOYSA-N urobilinogen Chemical compound CCC1=C(C)C(=O)NC1CC1=C(C)C(CCC(O)=O)=C(CC2=C(C(C)=C(CC3C(=C(CC)C(=O)N3)C)N2)CCC(O)=O)N1 OBHRVMZSZIDDEK-UHFFFAOYSA-N 0.000 description 2
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Natural products OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 description 1
- 229960005070 ascorbic acid Drugs 0.000 description 1
- 235000010323 ascorbic acid Nutrition 0.000 description 1
- 239000011668 ascorbic acid Substances 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- TYQCGQRIZGCHNB-JLAZNSOCSA-N l-ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(O)=C(O)C1=O TYQCGQRIZGCHNB-JLAZNSOCSA-N 0.000 description 1
- 238000010339 medical test Methods 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
- G01N2001/317—Apparatus therefor spraying liquids onto surfaces
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00039—Transport arrangements specific to flat sample substrates, e.g. pusher blade
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00108—Test strips, e.g. paper
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00108—Test strips, e.g. paper
- G01N2035/00118—Test strips, e.g. paper for multiple tests
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Preventing Corrosion Or Incrustation Of Metals (AREA)
- Inert Electrodes (AREA)
- Secondary Cells (AREA)
- Catalysts (AREA)
- Eye Examination Apparatus (AREA)
- Investigating Materials By The Use Of Optical Means Adapted For Particular Applications (AREA)
Abstract
Description
iin
DK 166235BDK 166235B
oisland
Opfindelsen angår et apparat til befugtning af teststrimler, der har flere testområder,' således som de eksempelvis anvendes for medicinske test, især til undersøgelse af urin. Apparatet er del af en procesbane, der 5 tjener til automatisk tilførsel, sortering, befugtning og indlægning af teststrimler i et analyseapparat, eksempelvis et flerkanalfotometer.The invention relates to an apparatus for wetting test strips having multiple test areas, such as are used, for example, for medical tests, especially for the examination of urine. The apparatus is part of a process path which serves for automatic feeding, sorting, wetting and inserting test strips into an analyzer, for example a multichannel photometer.
Til den almindelig kendte urindiagnostik står til rådighed såkaldte multiteststrimler til bestemmelse af 10 bilirubin, urobilinogen, ketonlegemer, askorbinsyre, glukose, protein, nitrit, pH-værdien og blod. Sådanne teststrimler indeholder flere testområder, på hvilke de til den pågældende test hørende reagenser er anbragt som indikatorer. Teststrimlerne befugtes manuelt med urin og ind-15 lægges derefter i analysatoren. Dette arbejde skal automatiseres. Hertil kræves der bl.a. et apparat til befugtning af teststrimlerne.Commonly known urine diagnostics are available so-called multi-test strips for the determination of 10 bilirubin, urobilinogen, ketone bodies, ascorbic acid, glucose, protein, nitrite, pH and blood. Such test strips contain several test areas on which the reagents belonging to that test are placed as indicators. The test strips are manually wetted with urine and then loaded into the analyzer. This work needs to be automated. This requires, inter alia, an apparatus for wetting the test strips.
Et sådant apparat tilvejebringes ifølge opfindelsen ved, at der over et aflægningssted for teststrimlerne 20 er anbragt et parallelt med teststrimmelen forskydeligt forstøvningsaggregat, som er udstyret med en bredslidset dyse.Such an apparatus is provided in accordance with the invention in that a spraying assembly displaceable parallel to the test strip is provided over a deposition point for the test strips 20, which is equipped with a wide slotted nozzle.
Ved vedvarende bevægelse af forstøvningsaggregatet hen over testområderne er det ifølge opfindelsen hensigts-25 mæssigt, at forstøvningsaggregatet er udstyret med mindst ét bortsugningsorgan til bortsugning af overskydende væske mellem de enkelte testområder.In the case of continuous movement of the atomizer over the test regions, it is appropriate according to the invention that the atomizer be equipped with at least one suction device for suction of excess fluid between the individual test regions.
Vil man ikke have et sådant bortsugningsorgan, er det ifølge opfindelsen hensigtsmæssigt, at forstøvnings-30 aggregatet er udstyret med en trinfremfører, der er indrettet til, at den bredslidsede dyse for en k-ort tid kommer til stilstand over hvert testområde, hvorhos trinfremføreren kan være forbundet med en i forstøvningsaggregatets væskeførende del anbragt ventil for væsken.If one does not want such a suction device, it is appropriate according to the invention that the atomizer assembly is equipped with a step feeder which is arranged to allow the wide slotted nozzle to stand still for a short period of time over each test area where the step feeder can be connected to a valve for the liquid located in the liquid-carrying part of the atomizer.
35 En udførelsesform for apparatet ifølge opfindelsen skal i det følgende beskrives nærmere under henvisning tilAn embodiment of the apparatus according to the invention will now be described in more detail with reference to
DK 166235BDK 166235B
22
OISLAND
tegningen, på hvilken fig. 1 viser apparatet, hvis forstøvningsaggregat er forbundet med en trinfremfører, set fra siden og delvis i snit, 5 fig. 2 samme i skrå afbildning, fig. 3 samme, hvis forstøvningsaggregat bevæger sig vedvarende, og fig. 4 apparatet ifølge fig. 3 set oppefra.the drawing, in which FIG. 1 is a side view of the apparatus whose nebulizer assembly is connected to a step feeder; FIG. 2 shows the same in oblique view, FIG. 3 shows the same if the atomizer is moving continuously, and FIG. 4 the apparatus of FIG. 3 seen from above.
Ved det viste apparat til befugtning af teststrim-10 ler er der over et aflægningssted 1 for teststrimlerne anbragt et forstøvningsaggregat 3. Aggregatet har en bredslidset dyse 4, og det kan forskydes parallelt med teststrimmelen, så at dysen føres hen over de enkelte testområder 5. Ved trinvis fremføring af forstøvningsaggregatet ifølge fig. 1 15 er aggregatet udstyret med en trinfremfører 6, der sørger for, at dysen 4 hver gang kommer til stilstand over et testområde 5. Samtidig betjenes en ventil 7, der kan være anbragt i tilførselsledningen for væsken. Ventilen 7 kan være forbundet med trinfremføreren ad mekanisk eller elektrisk vej.At the apparatus shown for wetting test strips, a spraying assembly 3 is arranged above a deposition point 1 of the test strips. The assembly has a wide slotted nozzle 4 and it can be displaced parallel to the test strip so that the nozzle is passed over the individual test areas 5. By incrementally advancing the nebulizer assembly of FIG. 1 15, the assembly is equipped with a step feeder 6 which ensures that the nozzle 4 comes to a standstill each time over a test area 5. At the same time, a valve 7, which may be located in the supply line for the liquid, is operated. The valve 7 may be connected to the step feeder by mechanical or electrical means.
20 Den bredslidsede dyse 4 er hensigtsmæssigt tilpasset efter testområderne 5's geometri, så at der kan foregå en opsugning af væske ved testområdernes sider 8 fra det sugedygtige underlag 9 for reagensbæreren 10.The wide-slotted nozzle 4 is suitably adapted to the geometry of the test areas 5 so that liquid can be drawn up at the sides 8 of the test areas from the suction-support 9 for the reagent carrier 10.
Ved vedvarende fremføring hen over testområderne 5 25 må der sørges for, at overskydende væske mellem de enkelte testområder fjernes. I dette øjemed kan forstøvningsaggregatet være udstyret med mindst ét bortsugningsorgan 11.Continuous flow across test areas 5 25 must ensure that excess liquid between the individual test areas is removed. To this end, the atomizer may be equipped with at least one suction means 11.
Ifølge fig. 4 er apparatet udstyret med to bortsugningsorganer 11. Teststrimmelen består i reglen af et bæreorgan 12, 30 testområderne 5 og en netagtig overdækning til beskyttelse af testområderne, hvorhos testområdernes sideområder 8 forbliver ubeskyttet. Testområderne kan bestå af et sugedygtigt underlag 9 for reagensbæreren, og reagensbæreren 10, eller af en enkeltlaget reagensbærer, der er klæbet på en 35 bærefolie.According to FIG. 4, the apparatus is equipped with two suction means 11. The test strip usually consists of a carrier 12, the test areas 5 and a net-like cover for protecting the test areas, where the side areas 8 of the test areas remain unprotected. The test areas may consist of a suction-resistant substrate 9 for the reagent carrier and the reagent carrier 10, or of a single-layered reagent carrier adhered to a carrier film.
Claims (3)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19863625683 DE3625683A1 (en) | 1986-07-30 | 1986-07-30 | DEVICE FOR WETING TEST STRIPS |
| DE3625683 | 1986-07-30 |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK395887D0 DK395887D0 (en) | 1987-07-29 |
| DK395887A DK395887A (en) | 1988-01-31 |
| DK166235B true DK166235B (en) | 1993-03-22 |
| DK166235C DK166235C (en) | 1993-08-16 |
Family
ID=6306251
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK395887A DK166235C (en) | 1986-07-30 | 1987-07-29 | DEVICE FOR WETTING TEST STRIPS WITH MULTIPLE TEST AREAS |
Country Status (10)
| Country | Link |
|---|---|
| EP (1) | EP0255057B1 (en) |
| JP (1) | JPS6338162A (en) |
| AT (1) | ATE66746T1 (en) |
| AU (1) | AU7624587A (en) |
| CA (1) | CA1285753C (en) |
| DE (2) | DE3625683A1 (en) |
| DK (1) | DK166235C (en) |
| ES (1) | ES2025108B3 (en) |
| FI (1) | FI91452C (en) |
| NO (1) | NO172413C (en) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3905954C2 (en) * | 1989-02-25 | 2001-02-01 | Lohmann Therapie Syst Lts | Process for the visualization of substance stains on layer chromatograms |
| US5439649A (en) * | 1993-09-29 | 1995-08-08 | Biogenex Laboratories | Automated staining apparatus |
| DE4411661A1 (en) * | 1994-04-05 | 1995-10-12 | Schoettler Markus Dipl Geol | Multi-parameter video technical analysis process for fluid media |
| SE9904349D0 (en) * | 1999-11-30 | 1999-11-30 | Active Biotech Ab | Novel device |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2239685B1 (en) * | 1973-07-31 | 1978-09-22 | Olympus Optical Co |
-
1986
- 1986-07-30 DE DE19863625683 patent/DE3625683A1/en not_active Withdrawn
-
1987
- 1987-07-24 EP EP87110722A patent/EP0255057B1/en not_active Expired - Lifetime
- 1987-07-24 DE DE8787110722T patent/DE3772483D1/en not_active Expired - Fee Related
- 1987-07-24 ES ES87110722T patent/ES2025108B3/en not_active Expired - Lifetime
- 1987-07-24 AT AT87110722T patent/ATE66746T1/en not_active IP Right Cessation
- 1987-07-28 FI FI873293A patent/FI91452C/en not_active IP Right Cessation
- 1987-07-29 NO NO873181A patent/NO172413C/en unknown
- 1987-07-29 DK DK395887A patent/DK166235C/en not_active IP Right Cessation
- 1987-07-29 AU AU76245/87A patent/AU7624587A/en not_active Abandoned
- 1987-07-29 JP JP62187877A patent/JPS6338162A/en active Pending
- 1987-07-29 CA CA000543287A patent/CA1285753C/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| NO873181L (en) | 1988-02-01 |
| NO172413B (en) | 1993-04-05 |
| DK166235C (en) | 1993-08-16 |
| FI873293A (en) | 1988-01-31 |
| NO172413C (en) | 1993-07-14 |
| ES2025108B3 (en) | 1992-03-16 |
| JPS6338162A (en) | 1988-02-18 |
| EP0255057B1 (en) | 1991-08-28 |
| DE3625683A1 (en) | 1988-02-11 |
| EP0255057A2 (en) | 1988-02-03 |
| NO873181D0 (en) | 1987-07-29 |
| ATE66746T1 (en) | 1991-09-15 |
| FI91452C (en) | 1994-06-27 |
| DK395887A (en) | 1988-01-31 |
| AU7624587A (en) | 1988-02-04 |
| DK395887D0 (en) | 1987-07-29 |
| FI873293A0 (en) | 1987-07-28 |
| FI91452B (en) | 1994-03-15 |
| EP0255057A3 (en) | 1989-06-14 |
| CA1285753C (en) | 1991-07-09 |
| DE3772483D1 (en) | 1991-10-02 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |