DK1637537T3 - New medicines - Google Patents

New medicines

Info

Publication number
DK1637537T3
DK1637537T3 DK05020152T DK05020152T DK1637537T3 DK 1637537 T3 DK1637537 T3 DK 1637537T3 DK 05020152 T DK05020152 T DK 05020152T DK 05020152 T DK05020152 T DK 05020152T DK 1637537 T3 DK1637537 T3 DK 1637537T3
Authority
DK
Denmark
Prior art keywords
carboxylic acid
acid derivatives
new
sic
analogs
Prior art date
Application number
DK05020152T
Other languages
Danish (da)
Inventor
Dagmar Braun
Original Assignee
Riemser Arzneimittel Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Riemser Arzneimittel Ag filed Critical Riemser Arzneimittel Ag
Application granted granted Critical
Publication of DK1637537T3 publication Critical patent/DK1637537T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/14—Quaternary ammonium compounds, e.g. edrophonium, choline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • C07F9/65522—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)

Abstract

Xanthene carboxylic acid derivatives or analogs (II) and their salts are new. Xanthene carboxylic acid derivatives or analogs of formula (II) and their salts are new. R1, R2 and R3hydrogen, Me, Et or propyl; n (sic) : 1-3; Z : (CH2)m; m : 1-5; X-> (sic) : F->, Cl->, Br->, I->, H2PO4->, CO32->, SO42->, HPO42-> or PO43-> An independent claim is also included for use of (II), methanthelinium bromide and xanthene carboxylic acid derivatives of formula (I) for reducing or inhibiting the retching response. [Image] ACTIVITY : Antiemetic. MECHANISM OF ACTION : Ganglion blocker.
DK05020152T 2004-09-17 2005-09-15 New medicines DK1637537T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102004045220A DE102004045220A1 (en) 2004-09-17 2004-09-17 New medicines

Publications (1)

Publication Number Publication Date
DK1637537T3 true DK1637537T3 (en) 2007-08-27

Family

ID=35453573

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05020152T DK1637537T3 (en) 2004-09-17 2005-09-15 New medicines

Country Status (6)

Country Link
EP (1) EP1637537B1 (en)
AT (1) ATE361307T1 (en)
DE (2) DE102004045220A1 (en)
DK (1) DK1637537T3 (en)
ES (1) ES2285619T3 (en)
PL (1) PL1637537T3 (en)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL73242C (en) * 1949-03-09
US2659732A (en) * 1952-05-10 1953-11-17 Searle & Co Quaternary ammonium salts of dialkyl aminoalkyl xanthene-9-carboxylates and the production thereof
DE1044102B (en) * 1953-07-08 1958-11-20 Christian Brunnengraeber Chem Process for the preparation of esters of xanthene-9-carboxylic acid
DE1793364A1 (en) * 1968-09-06 1972-01-27 Asta Werke Ag Chem Fab Basic alpha-nortricyclyl- (3) -benzyl-ethers, their quaternary salts and N-oxides and pharmaceutical products made therefrom
BE788289A (en) * 1971-09-03 1973-01-02 Richter Gedeon Vegyeszet PHARMACOLOGICALLY ACTIVE ESTERS AND SALTS OF AMINOALCOOLS AND THEIR PREPARATION PROCESS

Also Published As

Publication number Publication date
ES2285619T3 (en) 2007-11-16
PL1637537T3 (en) 2007-09-28
DE502005000652D1 (en) 2007-06-14
DE102004045220A1 (en) 2006-04-06
EP1637537A1 (en) 2006-03-22
EP1637537B1 (en) 2007-05-02
ATE361307T1 (en) 2007-05-15

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