DK1572931T3 - Fremgangsmåder og sammensætninger til modulering og påvisning af WISP-aktivitet - Google Patents
Fremgangsmåder og sammensætninger til modulering og påvisning af WISP-aktivitetInfo
- Publication number
- DK1572931T3 DK1572931T3 DK03739341.0T DK03739341T DK1572931T3 DK 1572931 T3 DK1572931 T3 DK 1572931T3 DK 03739341 T DK03739341 T DK 03739341T DK 1572931 T3 DK1572931 T3 DK 1572931T3
- Authority
- DK
- Denmark
- Prior art keywords
- wisp
- modulating
- compositions
- methods
- activity
- Prior art date
Links
- 230000000694 effects Effects 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- 101100014709 Drosophila melanogaster wisp gene Proteins 0.000 title 1
- 101710137353 CCN family member 4 Proteins 0.000 abstract 5
- 102100031173 CCN family member 4 Human genes 0.000 abstract 5
- 229920001184 polypeptide Polymers 0.000 abstract 2
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 2
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 2
- 102100032912 CD44 antigen Human genes 0.000 abstract 1
- 101000777560 Homo sapiens CCN family member 4 Proteins 0.000 abstract 1
- 101000868273 Homo sapiens CD44 antigen Proteins 0.000 abstract 1
- 239000005557 antagonist Substances 0.000 abstract 1
- 102000037865 fusion proteins Human genes 0.000 abstract 1
- 108020001507 fusion proteins Proteins 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
- 230000001575 pathological effect Effects 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/22—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against growth factors ; against growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Gastroenterology & Hepatology (AREA)
- Neurosurgery (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Oncology (AREA)
- Pulmonology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US39265202P | 2002-06-29 | 2002-06-29 | |
| US40873902P | 2002-09-06 | 2002-09-06 | |
| PCT/US2003/020407 WO2004003158A2 (en) | 2002-06-29 | 2003-06-28 | Methods and compositions for modulating and detecting wisp activity |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1572931T3 true DK1572931T3 (da) | 2010-11-08 |
Family
ID=30003268
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK03739341.0T DK1572931T3 (da) | 2002-06-29 | 2003-06-28 | Fremgangsmåder og sammensætninger til modulering og påvisning af WISP-aktivitet |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US7456262B2 (da) |
| EP (1) | EP1572931B1 (da) |
| JP (1) | JP4636497B2 (da) |
| AT (1) | ATE476447T1 (da) |
| AU (1) | AU2003245733B2 (da) |
| CA (1) | CA2489515C (da) |
| DE (1) | DE60333669D1 (da) |
| DK (1) | DK1572931T3 (da) |
| IL (1) | IL165776A (da) |
| WO (1) | WO2004003158A2 (da) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4636497B2 (ja) | 2002-06-29 | 2011-02-23 | ジェネンテック， インコーポレイテッド | Ｗｉｓｐ活性を調節し検出するための方法及び組成物 |
| US7455834B2 (en) | 2002-06-29 | 2008-11-25 | Genentech, Inc. | Methods and compositions for modulating and detecting WISP activity |
| AU2004272066B8 (en) * | 2003-09-11 | 2010-08-05 | Genentech, Inc. | Methods of using WISP antagonists |
| US8460658B2 (en) | 2003-10-10 | 2013-06-11 | Alchemia Oncology Pty Limited | Method of treating cancer and/or cellular proliferative conditions and agents targeting hyaluronan anabolism useful for same |
| NZ546272A (en) * | 2003-10-10 | 2009-05-31 | Alchemia Oncology Pty Ltd | The modulation of hyaluronan synthesis and degradation in the treatment of disease |
| US8119397B2 (en) * | 2004-03-31 | 2012-02-21 | Two Cells Co., Ltd. | Therapeutic agents and therapeutic methods for treating injured tissue |
| CN113087772B (zh) * | 2021-04-27 | 2022-04-22 | 清华大学深圳国际研究生院 | 一种rhamm拮抗多肽及其衍生物与应用 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE406441T1 (de) * | 1997-10-29 | 2008-09-15 | Genentech Inc | Verwendung des wnt-1 induzierten sekretierten polypeptids wisp-1 |
| ATE380195T1 (de) * | 1999-03-08 | 2007-12-15 | Genentech Inc | Zusammensetzungen und verfahren zur behandlung von tumoren |
| JP4636497B2 (ja) | 2002-06-29 | 2011-02-23 | ジェネンテック， インコーポレイテッド | Ｗｉｓｐ活性を調節し検出するための方法及び組成物 |
| AU2004272066B8 (en) | 2003-09-11 | 2010-08-05 | Genentech, Inc. | Methods of using WISP antagonists |
-
2003
- 2003-06-28 JP JP2004549836A patent/JP4636497B2/ja not_active Expired - Lifetime
- 2003-06-28 WO PCT/US2003/020407 patent/WO2004003158A2/en active Search and Examination
- 2003-06-28 DE DE60333669T patent/DE60333669D1/de not_active Expired - Lifetime
- 2003-06-28 DK DK03739341.0T patent/DK1572931T3/da active
- 2003-06-28 CA CA2489515A patent/CA2489515C/en not_active Expired - Fee Related
- 2003-06-28 AU AU2003245733A patent/AU2003245733B2/en not_active Ceased
- 2003-06-28 US US10/519,621 patent/US7456262B2/en not_active Expired - Lifetime
- 2003-06-28 AT AT03739341T patent/ATE476447T1/de active
- 2003-06-28 EP EP03739341A patent/EP1572931B1/en not_active Expired - Lifetime
-
2004
- 2004-12-15 IL IL165776A patent/IL165776A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| AU2003245733B2 (en) | 2009-11-26 |
| CA2489515C (en) | 2013-01-22 |
| JP4636497B2 (ja) | 2011-02-23 |
| WO2004003158A2 (en) | 2004-01-08 |
| CA2489515A1 (en) | 2004-01-08 |
| AU2003245733A1 (en) | 2004-01-19 |
| IL165776A0 (en) | 2006-01-15 |
| ATE476447T1 (de) | 2010-08-15 |
| US7456262B2 (en) | 2008-11-25 |
| US20060073135A1 (en) | 2006-04-06 |
| EP1572931A2 (en) | 2005-09-14 |
| WO2004003158A3 (en) | 2005-08-04 |
| EP1572931B1 (en) | 2010-08-04 |
| IL165776A (en) | 2010-06-30 |
| JP2006516956A (ja) | 2006-07-13 |
| EP1572931A4 (en) | 2006-03-01 |
| DE60333669D1 (de) | 2010-09-16 |
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