DK1516061T3 - Method for identifying agonists or antagonists for the GPR45like / GPR63 receptor - Google Patents

Method for identifying agonists or antagonists for the GPR45like / GPR63 receptor

Info

Publication number
DK1516061T3
DK1516061T3 DK03740154T DK03740154T DK1516061T3 DK 1516061 T3 DK1516061 T3 DK 1516061T3 DK 03740154 T DK03740154 T DK 03740154T DK 03740154 T DK03740154 T DK 03740154T DK 1516061 T3 DK1516061 T3 DK 1516061T3
Authority
DK
Denmark
Prior art keywords
gpr45like
antagonists
identifying agonists
gpr63 receptor
gpr63
Prior art date
Application number
DK03740154T
Other languages
Danish (da)
Inventor
Johann Gassenhuber
Evi Kostenis
Original Assignee
Sanofi Aventis Deutschland
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis Deutschland filed Critical Sanofi Aventis Deutschland
Application granted granted Critical
Publication of DK1516061T3 publication Critical patent/DK1516061T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/47—Assays involving proteins of known structure or function as defined in the subgroups
    • G01N2333/4701—Details
    • G01N2333/4719—G-proteins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention relates to a method for identifying a compound, which modifies the activity of the G-protein coupled GPR45-like/GPR63 receptor.
DK03740154T 2002-06-08 2003-05-28 Method for identifying agonists or antagonists for the GPR45like / GPR63 receptor DK1516061T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10225651A DE10225651A1 (en) 2002-06-08 2002-06-08 Method of identifying agonists or antagonists for the GPR45like / GPR63 receptor
PCT/EP2003/005600 WO2003104480A1 (en) 2002-06-08 2003-05-28 Method for identifying agonists or antagonists for the gpr45-like/gpr63 receptor

Publications (1)

Publication Number Publication Date
DK1516061T3 true DK1516061T3 (en) 2009-01-19

Family

ID=29594349

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03740154T DK1516061T3 (en) 2002-06-08 2003-05-28 Method for identifying agonists or antagonists for the GPR45like / GPR63 receptor

Country Status (9)

Country Link
EP (1) EP1516061B1 (en)
JP (1) JP4472521B2 (en)
AT (1) ATE403738T1 (en)
AU (1) AU2003274087A1 (en)
CA (1) CA2488883A1 (en)
DE (2) DE10225651A1 (en)
DK (1) DK1516061T3 (en)
ES (1) ES2311102T3 (en)
WO (1) WO2003104480A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106544359B (en) * 2015-09-22 2019-07-19 复旦大学 The purposes of GPR45 gene

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4138621A1 (en) * 1991-11-25 1993-06-17 Boehringer Ingelheim Int METHOD FOR SCREENING SUBSTANCES WITH MODULATING EFFECT ON A RECEPTACLE-RELATED CELLULAR SIGNAL TRANSMISSION PATH
KR100629185B1 (en) * 1997-11-11 2006-09-28 오노 야꾸힝 고교 가부시키가이샤 Human lysophosphatidic acid receptor and use thereof
US6126587A (en) * 1998-04-08 2000-10-03 U.S. Centrifuge Centrifugal separator apparatus including a plow blade assembly
AU4169499A (en) * 1998-06-22 2000-01-10 Japan Tobacco Inc. Novel g protein-coupled receptor protein, dna and use thereof
EP1196572A1 (en) * 1999-07-27 2002-04-17 Smithkline Beecham Plc Axor21, a g-protein coupled receptor
DE60131730T2 (en) * 2000-03-17 2008-11-20 The University Of Tennessee Research Corp., Knoxville AGONISTS AND ANTAGONISTS FOR THE LPA RECEPTOR AND APPLICATION METHODS
WO2002034781A1 (en) * 2000-10-20 2002-05-02 Solvay Pharmaceuticals Gmbh Human g-protein coupled diadenosine tetraphosphate receptor (ap4ar)

Also Published As

Publication number Publication date
CA2488883A1 (en) 2003-12-18
JP4472521B2 (en) 2010-06-02
AU2003274087A1 (en) 2003-12-22
EP1516061B1 (en) 2008-08-06
EP1516061A1 (en) 2005-03-23
DE50310285D1 (en) 2008-09-18
WO2003104480A1 (en) 2003-12-18
ES2311102T3 (en) 2009-02-01
DE10225651A1 (en) 2003-12-24
ATE403738T1 (en) 2008-08-15
JP2005528920A (en) 2005-09-29

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