DK1470227T3 - Process for the selective insertion of a double bond into a steroid skeleton - Google Patents

Process for the selective insertion of a double bond into a steroid skeleton

Info

Publication number
DK1470227T3
DK1470227T3 DK03704484T DK03704484T DK1470227T3 DK 1470227 T3 DK1470227 T3 DK 1470227T3 DK 03704484 T DK03704484 T DK 03704484T DK 03704484 T DK03704484 T DK 03704484T DK 1470227 T3 DK1470227 T3 DK 1470227T3
Authority
DK
Denmark
Prior art keywords
überexpression
dehydrogenasen
double bond
steroid skeleton
zur
Prior art date
Application number
DK03704484T
Other languages
Danish (da)
Inventor
Tilman Spellig
Original Assignee
Bayer Schering Pharma Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Schering Pharma Ag filed Critical Bayer Schering Pharma Ag
Application granted granted Critical
Publication of DK1470227T3 publication Critical patent/DK1470227T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P33/00—Preparation of steroids
    • C12P33/02—Dehydrogenating; Dehydroxylating

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Es wird ein Verfahren zur Überexpression von Dehydrogenasen, besonders zur Überexpression von DELTA1-Dehydrogenasen, insbesondere zur Überexpression von 3-Ketosteroid-DELTA1-Dehydrogenasen, sowie die für die Überexpression verwendbaren Bakterien, Plasmide und DNA-Sequenzen beschrieben.
DK03704484T 2002-02-01 2003-01-28 Process for the selective insertion of a double bond into a steroid skeleton DK1470227T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE10204798A DE10204798A1 (en) 2002-02-01 2002-02-01 Procedure for overexpression of dehydrogenases
PCT/EP2003/000855 WO2003064653A2 (en) 2002-02-01 2003-01-28 Method for overexpressing dehydrogenases

Publications (1)

Publication Number Publication Date
DK1470227T3 true DK1470227T3 (en) 2007-08-20

Family

ID=27588396

Family Applications (1)

Application Number Title Priority Date Filing Date
DK03704484T DK1470227T3 (en) 2002-02-01 2003-01-28 Process for the selective insertion of a double bond into a steroid skeleton

Country Status (9)

Country Link
EP (1) EP1470227B1 (en)
JP (1) JP4460300B2 (en)
AT (1) ATE359368T1 (en)
AU (1) AU2003206792A1 (en)
DE (2) DE10204798A1 (en)
DK (1) DK1470227T3 (en)
ES (1) ES2285095T3 (en)
PT (1) PT1470227E (en)
WO (1) WO2003064653A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100374570C (en) * 2004-07-07 2008-03-12 新疆农业科学院微生物应用研究所 Electric conversion method of making shuttle plasmid guide into yellow brevibacterium
CN101918436A (en) * 2007-11-16 2010-12-15 维莱尼姆公司 Compositions and methods for making androstenediones
CN106893753A (en) * 2015-12-21 2017-06-27 天津金耀集团有限公司 A kind of method that prednisolone is prepared by the step of biofermentation one
CN115927428A (en) * 2022-08-25 2023-04-07 天津科技大学 Gene rapid editing method, genetic operation system, strain and application applied to arthrobacter simplex

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3102080A (en) * 1960-05-20 1963-08-27 Schering Ag Method of producing 1,4-diene-3-ketosteroids
FR2657882B1 (en) * 1990-02-07 1994-08-12 Centre Nat Rech Scient DNA FRAGMENTS COMPRISING THE GENE OF 1-DEHYDROGENASE, MICROORGANISMS TRANSFORMED BY SAID FRAGMENTS AND APPLICATIONS OF SUCH FRAGMENTS AND MICROORGANISMS.

Also Published As

Publication number Publication date
WO2003064653A3 (en) 2003-12-24
DE50307011D1 (en) 2007-05-24
AU2003206792A1 (en) 2003-09-02
ATE359368T1 (en) 2007-05-15
EP1470227A2 (en) 2004-10-27
ES2285095T3 (en) 2007-11-16
DE10204798A1 (en) 2003-08-14
JP2006502692A (en) 2006-01-26
WO2003064653A2 (en) 2003-08-07
PT1470227E (en) 2007-07-23
EP1470227B1 (en) 2007-04-11
JP4460300B2 (en) 2010-05-12

Similar Documents

Publication Publication Date Title
DE502006003201D1 (en) METHOD FOR CONNECTING THE PUSH OF SEALING PROFILES AND DEVICE FOR THEIR IMPLEMENTATION
DE50313391D1 (en) UK MIXTURES, A METHOD FOR THE PRODUCTION THEREOF, METHOD FOR THE PRODUCTION OF COMPOSITE FORM PARTS AND THE USE THEREOF
DE69802712T2 (en) A COMPONENT SHAPED BY HIGH PRESSURE, AND METHOD AND DEVICE FOR THE PRODUCTION THEREOF
DE10346958A1 (en) Uretdione group-containing polyurethane compositions which are curable at low temperature
ATE497984T1 (en) DIMERCAPTAN-TERMINATED POLYTHIOETHER POLYMERS AND METHOD FOR THE PRODUCTION AND USE THEREOF
ATE321088T1 (en) POLYSILOXANE POLYMERS, METHOD FOR THEIR PRODUCTION AND THEIR USE
ATE513905T1 (en) METHOD FOR REPLICATION OF INFLUENZA IN CELL CULTURE AND THE INFLUENZA VIRUSES PRODUCED BY THIS METHOD
DE60142745D1 (en) REFLECTION-FREE OBJECT, A PROCESS FOR ITS MANUFACTURE AND A TRANSFER PART FOR THE REFLECTION-FREE OBJECT
ATE376451T1 (en) METHOD FOR GENERATING AN EMULSION BY USING MICROCHANNEL PROCESS TECHNOLOGY
ATE527012T1 (en) METHOD FOR PRODUCING MEDICAL DEVICES HAVING A SACRIFICIAL STRUCTURE
EP1900725A3 (en) Process for the preparation of azodicarbonamide
DE60217708D1 (en) METHOD FOR PRODUCING AN ELASTIC COMPOSITE MATERIAL
DE60317136D1 (en) Immunoassay method, reagent for immunoassay method and method for its production
ATE497509T1 (en) ELECTROSTERICALLY STABILIZED AQUEOUS POLYURETHANE RESINS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE
DE502004007637D1 (en) METHOD AND DEVICE FOR APPLYING A REINFORCEMENT TO A PLASTIC TUBE THROUGH A WINDING WELDING METHOD
DE59910952D1 (en) AQUEOUS 2C PUR SYSTEMS WITH INCREASED IMPACT AND GOOD RESISTANCE CHARACTERISTICS, A METHOD FOR THE PRODUCTION THEREOF AND THEIR USE
DK1470227T3 (en) Process for the selective insertion of a double bond into a steroid skeleton
EP0849355A3 (en) Powder washing and cleaning components
ATE430493T1 (en) MOIST SNUFF COMPOSITION CONTAINING AT LEAST ONE THICKENER AND METHOD FOR THE PRODUCTION THEREOF
DE60329952D1 (en) Polyurethane-ureas useful for the production of spandex and a process for its preparation
EP3581667A3 (en) Moulded parts made from a corrosion resistant and machinable alloy
DE60308388D1 (en) 5-ANDROSTEN-3-OLSTEROID INTERMEDIATE PRODUCTS AND METHOD FOR THE PRODUCTION THEREOF
DE602004014217D1 (en) Procedure for the recovery of land pre-well
ATE267779T1 (en) WOOD WOOL COMPONENT AND METHOD FOR PRODUCING IT
ATE302301T1 (en) SUPPORTLESS LINOLEUM SURFACE AND METHOD FOR PRODUCING SAME