DK141116B - Analogifremgangsmåde til fremstilling af en di-(2-acetoxybenzoyl)-ester af 1,8,9-trihydroxyanthracen eller en 9-anthrontautomer deraf. - Google Patents
Analogifremgangsmåde til fremstilling af en di-(2-acetoxybenzoyl)-ester af 1,8,9-trihydroxyanthracen eller en 9-anthrontautomer deraf. Download PDFInfo
- Publication number
- DK141116B DK141116B DK587672AA DK587672A DK141116B DK 141116 B DK141116 B DK 141116B DK 587672A A DK587672A A DK 587672AA DK 587672 A DK587672 A DK 587672A DK 141116 B DK141116 B DK 141116B
- Authority
- DK
- Denmark
- Prior art keywords
- trihydroxyanthracene
- preparation
- acetoxybenzoyl
- ester
- anthronutomer
- Prior art date
Links
- 150000002148 esters Chemical class 0.000 title description 8
- YUTJCNNFTOIOGT-UHFFFAOYSA-N anthracene-1,8,9-triol Chemical compound C1=CC(O)=C2C(O)=C3C(O)=CC=CC3=CC2=C1 YUTJCNNFTOIOGT-UHFFFAOYSA-N 0.000 title description 6
- 238000000034 method Methods 0.000 title description 6
- 238000002360 preparation method Methods 0.000 title description 6
- -1 2-acetoxybenzoyl Chemical group 0.000 title description 2
- 230000003902 lesion Effects 0.000 description 9
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 description 6
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 description 4
- 208000003251 Pruritus Diseases 0.000 description 4
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 4
- 229960002311 dithranol Drugs 0.000 description 4
- 230000007794 irritation Effects 0.000 description 4
- 230000007803 itching Effects 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- 238000000926 separation method Methods 0.000 description 4
- 206010015946 Eye irritation Diseases 0.000 description 3
- 201000004681 Psoriasis Diseases 0.000 description 3
- YXFVVABEGXRONW-UHFFFAOYSA-N Toluene Chemical compound CC1=CC=CC=C1 YXFVVABEGXRONW-UHFFFAOYSA-N 0.000 description 3
- NUZWLKWWNNJHPT-UHFFFAOYSA-N anthralin Chemical class C1C2=CC=CC(O)=C2C(=O)C2=C1C=CC=C2O NUZWLKWWNNJHPT-UHFFFAOYSA-N 0.000 description 3
- 231100000013 eye irritation Toxicity 0.000 description 3
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 description 3
- DSGKWFGEUBCEIE-UHFFFAOYSA-N (2-carbonochloridoylphenyl) acetate Chemical compound CC(=O)OC1=CC=CC=C1C(Cl)=O DSGKWFGEUBCEIE-UHFFFAOYSA-N 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 2
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 2
- 239000005909 Kieselgur Substances 0.000 description 2
- 239000004927 clay Substances 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 150000005690 diesters Chemical class 0.000 description 2
- 238000004299 exfoliation Methods 0.000 description 2
- 239000000203 mixture Substances 0.000 description 2
- 239000000741 silica gel Substances 0.000 description 2
- 229910002027 silica gel Inorganic materials 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 238000004809 thin layer chromatography Methods 0.000 description 2
- 150000005691 triesters Chemical class 0.000 description 2
- NGNBDVOYPDDBFK-UHFFFAOYSA-N 2-[2,4-di(pentan-2-yl)phenoxy]acetyl chloride Chemical compound CCCC(C)C1=CC=C(OCC(Cl)=O)C(C(C)CCC)=C1 NGNBDVOYPDDBFK-UHFFFAOYSA-N 0.000 description 1
- 208000033856 Chemical eye injury Diseases 0.000 description 1
- CTQNGGLPUBDAKN-UHFFFAOYSA-N O-Xylene Chemical compound CC1=CC=CC=C1C CTQNGGLPUBDAKN-UHFFFAOYSA-N 0.000 description 1
- 241000364057 Peoria Species 0.000 description 1
- 206010037888 Rash pustular Diseases 0.000 description 1
- 125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 239000003054 catalyst Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 238000004440 column chromatography Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 239000006185 dispersion Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000011010 flushing procedure Methods 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 235000015243 ice cream Nutrition 0.000 description 1
- 206010023332 keratitis Diseases 0.000 description 1
- 238000004949 mass spectrometry Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 239000012299 nitrogen atmosphere Substances 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 208000029561 pustule Diseases 0.000 description 1
- 239000012265 solid product Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 230000003442 weekly effect Effects 0.000 description 1
- 239000008096 xylene Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/78—Benzoic acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/49—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups
- C07C205/57—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by carboxyl groups having nitro groups and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
- C07C69/88—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with esterified carboxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/84—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring
- C07C69/92—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic ring with etherified hydroxyl groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/22—Ortho- or ortho- and peri-condensed systems containing three rings containing only six-membered rings
- C07C2603/24—Anthracenes; Hydrogenated anthracenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB5492771 | 1971-11-26 | ||
| GB5492771A GB1361879A (en) | 1971-11-26 | 1971-11-26 | Benzoyl esters of 1,8,9-trihydroxy-anthracene processes for their preparation and compositions incorporating them |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DK141116B true DK141116B (da) | 1980-01-21 |
| DK141116C DK141116C (enrdf_load_stackoverflow) | 1980-06-30 |
Family
ID=10472486
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK587672AA DK141116B (da) | 1971-11-26 | 1972-11-24 | Analogifremgangsmåde til fremstilling af en di-(2-acetoxybenzoyl)-ester af 1,8,9-trihydroxyanthracen eller en 9-anthrontautomer deraf. |
Country Status (14)
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2426971A1 (fr) * | 1978-05-26 | 1979-12-21 | Peugeot | Dispositif contacteur electrique associe a un levier de commande |
| US4843097A (en) * | 1984-06-13 | 1989-06-27 | Groupement D'interet Economique Dit: Centre International De Recherches Dermatologiques C.I.R.D. | 10-aryl-1,8-dihydroxy-9-anthrones and their esters, process for preparing same, and use of same in human and veterinary medicine and in cosmetics |
| FR2591222B1 (fr) * | 1985-12-11 | 1988-07-22 | Cird | Mono, di et tri-esters de dihydroxy-1,8 phenyl-10 anthrone-9 ou anthranol-9, leur procede de preparation et leur utilisation en medecine humaine ou veterinaire et en cosmetique |
| JP6255210B2 (ja) * | 2013-10-24 | 2017-12-27 | アーゼッド・エレクトロニック・マテリアルズ（ルクセンブルグ）ソシエテ・ア・レスポンサビリテ・リミテ | レジスト下層膜形成組成物 |
-
0
- BE BE791643D patent/BE791643A/xx not_active IP Right Cessation
-
1971
- 1971-11-26 GB GB5492771A patent/GB1361879A/en not_active Expired
-
1972
- 1972-11-22 NL NL7215802A patent/NL7215802A/xx not_active Application Discontinuation
- 1972-11-23 IE IE1633/72A patent/IE37193B1/xx unknown
- 1972-11-23 PL PL1972159046A patent/PL89681B1/pl unknown
- 1972-11-23 CS CS7976A patent/CS161968B2/cs unknown
- 1972-11-24 FR FR7241854A patent/FR2161058B1/fr not_active Expired
- 1972-11-24 HU HUSE1652A patent/HU167374B/hu unknown
- 1972-11-24 CH CH1713572A patent/CH584181A5/xx not_active IP Right Cessation
- 1972-11-24 FI FI3329/72A patent/FI56371C/fi active
- 1972-11-24 DK DK587672AA patent/DK141116B/da not_active IP Right Cessation
- 1972-11-24 SE SE7215395A patent/SE400548B/xx unknown
- 1972-11-24 CA CA157,483A patent/CA996134A/en not_active Expired
- 1972-11-27 JP JP11816272A patent/JPS5531766B2/ja not_active Expired
-
1976
- 1976-05-11 SE SE7605364A patent/SE7605364L/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR2161058A1 (enrdf_load_stackoverflow) | 1973-07-06 |
| PL89681B1 (enrdf_load_stackoverflow) | 1976-12-31 |
| IE37193L (en) | 1973-05-26 |
| CA996134A (en) | 1976-08-31 |
| CH584181A5 (enrdf_load_stackoverflow) | 1977-01-31 |
| CS161968B2 (enrdf_load_stackoverflow) | 1975-06-10 |
| JPS4862749A (enrdf_load_stackoverflow) | 1973-09-01 |
| FI56371C (fi) | 1980-01-10 |
| GB1361879A (en) | 1974-07-30 |
| DE2257442A1 (de) | 1973-05-30 |
| FR2161058B1 (enrdf_load_stackoverflow) | 1976-04-23 |
| NL7215802A (enrdf_load_stackoverflow) | 1973-05-29 |
| BE791643A (fr) | 1973-03-16 |
| IE37193B1 (en) | 1977-05-25 |
| SE400548B (sv) | 1978-04-03 |
| SE7605364L (sv) | 1976-05-11 |
| DK141116C (enrdf_load_stackoverflow) | 1980-06-30 |
| DE2257442B2 (de) | 1977-03-10 |
| HU167374B (enrdf_load_stackoverflow) | 1975-09-27 |
| FI56371B (fi) | 1979-09-28 |
| JPS5531766B2 (enrdf_load_stackoverflow) | 1980-08-20 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PBP | Patent lapsed |