DK140288D0 - METHOD OF CLEANING PLASMINOGEN ACTIVATOR - Google Patents

METHOD OF CLEANING PLASMINOGEN ACTIVATOR

Info

Publication number
DK140288D0
DK140288D0 DK140288A DK140288A DK140288D0 DK 140288 D0 DK140288 D0 DK 140288D0 DK 140288 A DK140288 A DK 140288A DK 140288 A DK140288 A DK 140288A DK 140288 D0 DK140288 D0 DK 140288D0
Authority
DK
Denmark
Prior art keywords
cleaning
plasminogen activator
plasminogen
activator
cleaning plasminogen
Prior art date
Application number
DK140288A
Other languages
Danish (da)
Other versions
DK140288A (en
Inventor
Andrew Charles Kenney
Angela Joyce Perry
Susan White
Fiona Angela Olinda Marston
Original Assignee
Celltech Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB868617394A external-priority patent/GB8617394D0/en
Priority claimed from GB878709288A external-priority patent/GB8709288D0/en
Application filed by Celltech Ltd filed Critical Celltech Ltd
Publication of DK140288D0 publication Critical patent/DK140288D0/en
Publication of DK140288A publication Critical patent/DK140288A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6456—Plasminogen activators
    • C12N9/6459—Plasminogen activators t-plasminogen activator (3.4.21.68), i.e. tPA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
DK140288A 1986-07-16 1988-03-15 METHOD OF CLEANING PLASMINOGEN ACTIVATOR DK140288A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB868617394A GB8617394D0 (en) 1986-07-16 1986-07-16 Purification process
GB878709288A GB8709288D0 (en) 1987-04-16 1987-04-16 Purification process
PCT/GB1987/000498 WO1988000615A1 (en) 1986-07-16 1987-07-15 Process for purifying a plasminogen activator

Publications (2)

Publication Number Publication Date
DK140288D0 true DK140288D0 (en) 1988-03-15
DK140288A DK140288A (en) 1988-04-28

Family

ID=26291050

Family Applications (1)

Application Number Title Priority Date Filing Date
DK140288A DK140288A (en) 1986-07-16 1988-03-15 METHOD OF CLEANING PLASMINOGEN ACTIVATOR

Country Status (5)

Country Link
EP (1) EP0275282A1 (en)
JP (1) JPH01500563A (en)
AU (1) AU7709287A (en)
DK (1) DK140288A (en)
WO (1) WO1988000615A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4960702A (en) * 1985-09-06 1990-10-02 Codon Methods for recovery of tissue plasminogen activator
JPS6379591A (en) * 1986-09-22 1988-04-09 Mitsui Toatsu Chem Inc Purification of tpa
DE3832898A1 (en) * 1988-09-28 1990-04-12 Boehringer Mannheim Gmbh PRAEPARATE OF EXPRESSED PLASMINOGEN ACTIVATOR IN PROKARYONS
US20090130714A1 (en) * 2007-09-24 2009-05-21 Reliance Life Sciences Pvt.Ltd. Process for purifying recombinanat tissue plasminogen activator (TPA)

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5935B2 (en) * 1977-06-03 1984-01-05 住友化学工業株式会社 Purification method of urokinase
DE3015699C2 (en) * 1979-04-26 1982-07-15 Asahi Kasei Kogyo K.K., Osaka Manufacture of a plasminogen activator
WO1984001786A1 (en) * 1982-10-28 1984-05-10 Beecham Group Plc Enzyme derivatives and their use in the treatment of thrombosis
GB2138824B (en) * 1982-10-29 1986-12-31 Mitsui Toatsu Chemicals Novel plasminogen activator process for its preparation and thrombolytic drug containing the same
EP0163751B1 (en) * 1984-06-05 1989-09-20 Asahi Kasei Kogyo Kabushiki Kaisha Process for the preparation of a plasminogen activator
IE81135B1 (en) * 1984-10-01 2000-03-22 Genzyme Corp Recombinant DNA techniques and the products thereof
JPS61221128A (en) * 1985-03-26 1986-10-01 Snow Brand Milk Prod Co Ltd Monoclonal antibody against plasminogen activator, preparation thereof and method of using same
EP0238551A4 (en) * 1985-09-06 1988-02-01 Codon Methods for the recovery of tissue plasminogen activator.

Also Published As

Publication number Publication date
AU7709287A (en) 1988-02-10
WO1988000615A1 (en) 1988-01-28
JPH01500563A (en) 1989-03-01
EP0275282A1 (en) 1988-07-27
DK140288A (en) 1988-04-28

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment