DK139943B - Process for the preparation of triazolo (4,3a) (1,4) benzodiazepine-5N-oxide derivatives or acid addition salts thereof. - Google Patents

Process for the preparation of triazolo (4,3a) (1,4) benzodiazepine-5N-oxide derivatives or acid addition salts thereof.

Info

Publication number
DK139943B
DK139943B DK275072AA DK275072A DK139943B DK 139943 B DK139943 B DK 139943B DK 275072A A DK275072A A DK 275072AA DK 275072 A DK275072 A DK 275072A DK 139943 B DK139943 B DK 139943B
Authority
DK
Denmark
Prior art keywords
benzodiazepine
triazolo
preparation
acid addition
addition salts
Prior art date
Application number
DK275072AA
Other languages
Danish (da)
Other versions
DK139943C (en
Inventor
Yutaka Kuwada
Kanji Meguro
Hiroyuki Tawada
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP3970071A external-priority patent/JPS547800B1/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of DK139943B publication Critical patent/DK139943B/en
Application granted granted Critical
Publication of DK139943C publication Critical patent/DK139943C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/92—Oxygen atoms with hetero atoms directly attached to nitrogen atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DK275072AA 1971-06-05 1972-06-02 Process for the preparation of triazolo (4,3a) (1,4) benzodiazepine-5N-oxide derivatives or acid addition salts thereof. DK139943B (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP3970071A JPS547800B1 (en) 1971-06-05 1971-06-05
US25599372A 1972-05-23 1972-05-23
US482798A US3927015A (en) 1971-06-05 1974-06-24 2-(3-Hydroxyaminomethyl-S-triazol-4-yl)benzophenones

Publications (2)

Publication Number Publication Date
DK139943B true DK139943B (en) 1979-05-21
DK139943C DK139943C (en) 1979-10-15

Family

ID=27290236

Family Applications (1)

Application Number Title Priority Date Filing Date
DK275072AA DK139943B (en) 1971-06-05 1972-06-02 Process for the preparation of triazolo (4,3a) (1,4) benzodiazepine-5N-oxide derivatives or acid addition salts thereof.

Country Status (7)

Country Link
US (2) US3927015A (en)
AT (1) AT329566B (en)
CA (1) CA995214A (en)
CH (1) CH581656A5 (en)
DK (1) DK139943B (en)
NL (1) NL7207623A (en)
SE (1) SE397831B (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3332830A1 (en) * 1982-09-16 1984-03-22 The Upjohn Co., 49001 Kalamazoo, Mich. USE OF BENZODIAZEPINES TO COMBAT OR TREAT PANIC CONDITIONS
CN107698522A (en) * 2017-11-09 2018-02-16 华中药业股份有限公司 The preparation method of the phenylquinazoline of 6 chlorine, 3 amino, 3,4 dihydro, 4 hydroxyl 4
CN111689913B (en) * 2019-03-11 2023-03-28 浙江医药股份有限公司新昌制药厂 Chloroacetate of 5-chloro-2- (3-chloromethyl-S-triazolyl) benzophenone, and crystal form and preparation method thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3583978A (en) * 1968-09-26 1971-06-08 Hoffmann La Roche Preparation of 2,3-dihydro-1h-1,4-benzodiazepine 4-oxides
US3646011A (en) * 1969-04-25 1972-02-29 Hoffmann La Roche Preparation of 2 3-dihydro-1h-1 4-benzodiazepines 4-oxides
US3709898A (en) * 1971-02-09 1973-01-09 Upjohn Co Process for the production of triazolobenzodiazepines and intermediates

Also Published As

Publication number Publication date
CA995214A (en) 1976-08-17
NL7207623A (en) 1972-12-07
US3927015A (en) 1975-12-16
SE397831B (en) 1977-11-21
US4082764A (en) 1978-04-04
DK139943C (en) 1979-10-15
ATA483172A (en) 1975-08-15
AT329566B (en) 1976-05-25
CH581656A5 (en) 1976-11-15

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