DK1397124T3 - Use of diabetic agents for the manufacture of a medicament having a healing effect - Google Patents

Use of diabetic agents for the manufacture of a medicament having a healing effect

Info

Publication number
DK1397124T3
DK1397124T3 DK02748965T DK02748965T DK1397124T3 DK 1397124 T3 DK1397124 T3 DK 1397124T3 DK 02748965 T DK02748965 T DK 02748965T DK 02748965 T DK02748965 T DK 02748965T DK 1397124 T3 DK1397124 T3 DK 1397124T3
Authority
DK
Denmark
Prior art keywords
medicament
manufacture
healing effect
diabetic agents
insulin
Prior art date
Application number
DK02748965T
Other languages
Danish (da)
Inventor
Philippe Briet
Original Assignee
Merck Sante Sas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0108130A external-priority patent/FR2826278B1/en
Application filed by Merck Sante Sas filed Critical Merck Sante Sas
Application granted granted Critical
Publication of DK1397124T3 publication Critical patent/DK1397124T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/702—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/427—Thiazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/64—Sulfonylureas, e.g. glibenclamide, tolbutamide, chlorpropamide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/43—Enzymes; Proenzymes; Derivatives thereof
    • A61K38/46—Hydrolases (3)
    • A61K38/47—Hydrolases (3) acting on glycosyl compounds (3.2), e.g. cellulases, lactases
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention concerns the use of at least an antidiabetic selected among compounds stimulation insulin secretion, glucosidase inhibitors, thiazolidine-diones, insulin, agents enhancing insulin sensitivity, the glucagon-like peptide-1 (GLP-1), PPAR alpha / gamma agonists, meglitinide and aP2 inhibitors for making a medicine with cicatrizing effect.
DK02748965T 2001-06-20 2002-06-19 Use of diabetic agents for the manufacture of a medicament having a healing effect DK1397124T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29919601P 2001-06-20 2001-06-20
FR0108130A FR2826278B1 (en) 2001-06-20 2001-06-20 USE OF ANTIDIABETIC AGENTS FOR MANUFACTURING A MEDICAMENT HAVING A HEALING EFFECT
PCT/FR2002/002124 WO2003003971A2 (en) 2001-06-20 2002-06-19 Use of antidiabetics for making a medicine with cicatrizing effect

Publications (1)

Publication Number Publication Date
DK1397124T3 true DK1397124T3 (en) 2007-04-02

Family

ID=26213059

Family Applications (1)

Application Number Title Priority Date Filing Date
DK02748965T DK1397124T3 (en) 2001-06-20 2002-06-19 Use of diabetic agents for the manufacture of a medicament having a healing effect

Country Status (8)

Country Link
EP (1) EP1397124B1 (en)
AT (1) ATE346601T1 (en)
AU (1) AU2002319381A1 (en)
CY (1) CY1105822T1 (en)
DE (1) DE60216453T2 (en)
DK (1) DK1397124T3 (en)
ES (1) ES2275889T3 (en)
WO (1) WO2003003971A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2471363C (en) 2001-12-21 2014-02-11 Human Genome Sciences, Inc. Albumin fusion proteins
DE10214506A1 (en) * 2002-04-02 2003-10-16 Beiersdorf Ag Use of deoxynojirimycin and its derivatives for the treatment and prophylaxis of degenerative skin conditions
GB0303600D0 (en) * 2003-02-17 2003-03-19 Glaxo Group Ltd Novel therapeutic method and compositions

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3072527A (en) * 1959-07-01 1963-01-08 Horner Frank W Ltd Use of tolbutamide in the treatment of acne
DE2401450A1 (en) * 1973-01-16 1974-07-18 John James Voorhees PHARMACEUTICAL COMPOSITION FOR THE RELIEF OF SKIN PROLIFERATIONAL DISEASES
US4131652A (en) * 1977-06-22 1978-12-26 Deluccia Charles R Medicinal skin cream for psoriasis and method
US5145679A (en) * 1989-10-05 1992-09-08 Hinson Joan B Topical emollient for prevention and treatment of circulatory induced lesions
DE69230500D1 (en) * 1991-10-28 2000-02-03 Cytran Ltd Pharmaceutical dipeptide compositions and methods of use.
GB9701374D0 (en) * 1997-01-23 1997-03-12 Univ Liverpool Purinergic agonists and antagonists
US5929055A (en) * 1997-06-23 1999-07-27 The Research Foundation Of State University Of New York Therapeutic method for management of diabetes mellitus
JP2000212191A (en) * 1999-01-26 2000-08-02 Sankyo Co Ltd Phosphoric acid derivative
AR028299A1 (en) * 1999-09-17 2003-05-07 Novartis Ag A PHARMACEUTICAL COMPOSITION THAT INCLUDES NATEGLINIDA, A PROCESS FOR ITS PREPARATION AND THE USE OF SUCH COMPOSITION FOR THE PREPARATION OF A MEDICINAL PRODUCT FOR THE TREATMENT OF METABOLIC DISORDERS, ESPECIALLY DIABETES, OR A DISEASE OR CONDITION ASSOCIATED WITH DIABETY.
AU1133901A (en) * 1999-10-08 2001-04-23 Novartis Ag Method of treating metabolic disorders
FR2802814B1 (en) * 1999-12-23 2002-02-22 Aventis Pharma Sa COMBINATION OF DEOXYFRUCTOSAZINE AND AN ANTIDIABETIC FROM THE SULFONYLUREA FAMILY
US6582713B2 (en) * 2000-04-06 2003-06-24 Univ. Of Colorado - Colorado Springs Compositions and methods for promoting wound healing
PE20020323A1 (en) * 2000-08-22 2002-06-13 Novartis Ag PHARMACEUTICAL COMPOSITION INCLUDING AN INSULIN SECRETION ENHANCER AND HMG-Co-A-REDUCTASE INHIBITORS OR ANGIOTENSIN CONVERTER ENZYME (ACE) INHIBITORS

Also Published As

Publication number Publication date
DE60216453T2 (en) 2007-09-20
ATE346601T1 (en) 2006-12-15
ES2275889T3 (en) 2007-06-16
WO2003003971A3 (en) 2003-12-04
EP1397124B1 (en) 2006-11-29
DE60216453D1 (en) 2007-01-11
WO2003003971A2 (en) 2003-01-16
AU2002319381A1 (en) 2003-01-21
EP1397124A2 (en) 2004-03-17
CY1105822T1 (en) 2011-02-02

Similar Documents

Publication Publication Date Title
MY197569A (en) Gip/glp1 co-agonist compounds
AR022368A1 (en) PROCEDURE FOR MANAGING INSULINOTROPIC PEPTIDES
WO2006000567A3 (en) Use of glp-1 receptor agonists and / or dpp-iv inhibitors in combination with proton pump inhibitors and ppar agonists for the preparation of a medicament for the treatment of diabetes type i i and impaired pancreatic beta-cell function
BRPI0606727A (en) combination therapy for the treatment of diabetes and related conditions and for the treatment of improved conditions by increasing the level of glp-1 in the blood
DE60111570D1 (en) ISOINDOLIN-1-ON AS GLUCOKINASE ACTIVATORS
UA111742C2 (en) PHARMACEUTICAL COMPOSITIONS
MD3242887T2 (en) GIP and GLP-1 co-agonist compounds
DE60032331D1 (en) EXENDINE FOR GLUCAGON SUPPRESSION
DE68929217T2 (en) INSULINOTROPES HORMON
ATE534404T1 (en) DIPEPTIDYLPEPTIDASE IV INHIBITORS FOR THE TREATMENT OF DIABETES PATIENTS WITH SECONDARY FAILURE DUE TO SULFONYL UREAS
TR200100079T2 (en) Glucagon-like peptide-1, which increases the ß-cell response to glucose
DE69942307D1 (en) N-TERMINAL CHANGED GLP-1 ABÖMMLINGE
EP1551494A4 (en) Front-loading medical injector and syringes, syringe interfaces, syringe adapters and syringe plungers for use therewith
BR0314655A (en) Combination drug
AR008444A1 (en) EMPLOYMENT OF LEPTINE ANTAGONISTS FOR THE TREATMENT OF INSULIN RESISTANCE IN TYPE II DIABETES
UY28005A1 (en) INDOL -3-CARBOXAMIDS AS GLUCOQUINASE ACTIVATORS (GK)
RS52629B (en) Lixisenatide as add-on therapy to insulin glargine and metformin for treating type 2 diabetes
Houtsmuller et al. The influence of ticlopidine on the natural course of retinal vein occlusion.
TR200100773T2 (en) Diabetes treatment method using an aP2 inhibitor and combination
MX2022009149A (en) Gip/glp1 co-agonist compounds.
TR199902980T2 (en) Use of leptin antagonists for the treatment of diabetes.
DK1397124T3 (en) Use of diabetic agents for the manufacture of a medicament having a healing effect
TR200000133T2 (en) Treatment of diabetes (diabetic) with thiazolidinedione, insulin secretagogue and alpha glucosidase inhibitor.
ATE377424T1 (en) USE OF SILYMARIN AND CARBOPOL FOR REGENERATION OF PANCREAS TISSUE AND CELLS WITH ENDOCRINE SECRETION IMMEDIATELY DUE TO DIABETES MELLITUS
PE89199A1 (en) PHARMACEUTICAL COMPOSITION OF TIAZOLIDINADIONA AND AN ALPHA GLUCOSIDASE INHIBITOR FOR THE TREATMENT OF DIABETES