DK137276C - Analogifremgangsmaade til fremstilling af 1,2,3,4,10,10a-hexahydropyrazino(1,2-a)indol-2-carboxamidiner - Google Patents

Analogifremgangsmaade til fremstilling af 1,2,3,4,10,10a-hexahydropyrazino(1,2-a)indol-2-carboxamidiner

Info

Publication number
DK137276C
DK137276C DK629372A DK629372A DK137276C DK 137276 C DK137276 C DK 137276C DK 629372 A DK629372 A DK 629372A DK 629372 A DK629372 A DK 629372A DK 137276 C DK137276 C DK 137276C
Authority
DK
Denmark
Prior art keywords
carboxamidines
hexahydropyrazino
indol
preparation
analogical procedure
Prior art date
Application number
DK629372A
Other languages
English (en)
Other versions
DK137276B (da
Inventor
Rochus Jonas
Richard Unger
Hans-Jochen Schliep
Ernst Schorscher
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE2162422A external-priority patent/DE2162422A1/de
Priority claimed from DE2250493A external-priority patent/DE2250493A1/de
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of DK137276B publication Critical patent/DK137276B/da
Application granted granted Critical
Publication of DK137276C publication Critical patent/DK137276C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK629372A 1971-12-16 1972-12-15 Analogifremgangsmaade til fremstilling af 1,2,3,4,10,10a-hexahydropyrazino(1,2-a)indol-2-carboxamidiner DK137276C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE2162422A DE2162422A1 (de) 1971-12-16 1971-12-16 Pyrazinoindol-derivate und verfahren zu ihrer herstellung
DE2250493A DE2250493A1 (de) 1972-10-14 1972-10-14 Pyrazinoindol-derivate und verfahren zu ihrer herstellung

Publications (2)

Publication Number Publication Date
DK137276B DK137276B (da) 1978-02-13
DK137276C true DK137276C (da) 1978-07-17

Family

ID=25762171

Family Applications (1)

Application Number Title Priority Date Filing Date
DK629372A DK137276C (da) 1971-12-16 1972-12-15 Analogifremgangsmaade til fremstilling af 1,2,3,4,10,10a-hexahydropyrazino(1,2-a)indol-2-carboxamidiner

Country Status (19)

Country Link
US (1) US3853878A (da)
JP (2) JPS5417760B2 (da)
AT (1) AT322557B (da)
AU (1) AU464969B2 (da)
BE (1) BE792724A (da)
CA (1) CA998049A (da)
CH (1) CH582703A5 (da)
CS (1) CS161971B2 (da)
DD (1) DD102384A5 (da)
DK (1) DK137276C (da)
ES (1) ES409637A1 (da)
FR (1) FR2163554B1 (da)
GB (1) GB1356898A (da)
HU (1) HU164944B (da)
IL (1) IL40907A (da)
NL (1) NL7215584A (da)
RO (1) RO62850A (da)
SE (1) SE398122B (da)
YU (2) YU35257B (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2504531A1 (de) * 1975-02-04 1976-08-05 Merck Patent Gmbh Verfahren zur herstellung von indolinderivaten
DE2739723A1 (de) * 1977-09-03 1979-03-08 Merck Patent Gmbh 2-guanidinomethyl-indoline und verfahren zu ihrer herstellung
US4210590A (en) * 1978-01-06 1980-07-01 Mcneil Laboratories, Incorporated Reduction of indole compounds to indoline compounds
US4697016A (en) * 1984-10-26 1987-09-29 Ciba-Geigy Corporation Intermediates for the preparation of a carboxylic acid
GB9902047D0 (en) * 1999-01-29 1999-03-17 Cerebrus Ltd Chemical compounds XI

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3542780A (en) * 1967-07-25 1970-11-24 American Home Prod 2-amidino-1,2,3,4-tetrahydropyrazine(1,2-a)indoles

Also Published As

Publication number Publication date
AT322557B (de) 1975-05-26
CH582703A5 (da) 1976-12-15
US3853878A (en) 1974-12-10
SE398122B (sv) 1977-12-05
DD102384A5 (da) 1973-12-12
NL7215584A (da) 1973-06-19
YU314072A (en) 1980-04-30
CS161971B2 (da) 1975-06-10
JPS5417760B2 (da) 1979-07-02
IL40907A0 (en) 1973-01-30
FR2163554A1 (da) 1973-07-27
AU464969B2 (en) 1975-08-28
YU35257B (en) 1980-10-31
CA998049A (en) 1976-10-05
JPS4867299A (da) 1973-09-13
BE792724A (fr) 1973-06-14
FR2163554B1 (da) 1975-10-17
HU164944B (da) 1974-05-28
AU5022672A (en) 1974-06-20
DK137276B (da) 1978-02-13
JPS5484598A (en) 1979-07-05
GB1356898A (en) 1974-06-19
RO62850A (fr) 1977-11-15
IL40907A (en) 1975-07-28
ES409637A1 (es) 1976-03-01

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