DK136887A - PROSTACYCLINES, ANALOGUES THEREOF OR PROSTAGLANDINES AND THROMBOXAN ANTAGONISTS TO TREAT THROMBOTIC AND THROMBOEMBOLIC DISEASES - Google Patents

PROSTACYCLINES, ANALOGUES THEREOF OR PROSTAGLANDINES AND THROMBOXAN ANTAGONISTS TO TREAT THROMBOTIC AND THROMBOEMBOLIC DISEASES

Info

Publication number
DK136887A
DK136887A DK136887A DK136887A DK136887A DK 136887 A DK136887 A DK 136887A DK 136887 A DK136887 A DK 136887A DK 136887 A DK136887 A DK 136887A DK 136887 A DK136887 A DK 136887A
Authority
DK
Denmark
Prior art keywords
prostacyclines
prostaglandines
thromboxan
analogues
antagonists
Prior art date
Application number
DK136887A
Other languages
Danish (da)
Other versions
DK136887D0 (en
DK169017B1 (en
Inventor
Claus-Steffen Stuerzebecher
Bernd Raduechel
Werner Georg Witt
Werner Skuballa
Helmut Vorbrueggen
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of DK136887D0 publication Critical patent/DK136887D0/en
Publication of DK136887A publication Critical patent/DK136887A/en
Application granted granted Critical
Publication of DK169017B1 publication Critical patent/DK169017B1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A combination preparation which comprises a prostaglandin (PG), a prostacyclin (PC) or a prostacyclin analogue (PCA) and a thromboxane receptor antagonist (TXAA) is suitable for concomitant use for thrombotic and thromboembolic diseases states.
DK136887A 1985-07-19 1987-03-17 Combination preparation for concomitant use when treating thrombotic and thromboembolic clinical pictures, which preparation comprises prostacyclins, analogues thereof, or prostaglandins (PC/PCA/PG) and thromboxane receptor antagonists (TXAA), and the use of PC/PCA/PG and TXAA for producing a medicament. DK169017B1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19853526362 DE3526362A1 (en) 1985-07-19 1985-07-19 PROSTACYCLINE, YOUR ANALOGA OR PROSTAGLANDINE AND THROMBOXANANTAGONISTS FOR THE TREATMENT OF THROMBOTIC AND THROMBOEMBOLIC DISEASES
DE3526362 1985-07-19
PCT/DE1986/000260 WO1987000434A1 (en) 1985-07-19 1986-06-20 Prostacyclines, their analogues or prostaglandines and thromboxane antagonists for the treatment of thrombotic and thrombo-embolic illnesses
DE8600260 1986-06-20

Publications (3)

Publication Number Publication Date
DK136887D0 DK136887D0 (en) 1987-03-17
DK136887A true DK136887A (en) 1987-03-17
DK169017B1 DK169017B1 (en) 1994-08-01

Family

ID=6276548

Family Applications (1)

Application Number Title Priority Date Filing Date
DK136887A DK169017B1 (en) 1985-07-19 1987-03-17 Combination preparation for concomitant use when treating thrombotic and thromboembolic clinical pictures, which preparation comprises prostacyclins, analogues thereof, or prostaglandins (PC/PCA/PG) and thromboxane receptor antagonists (TXAA), and the use of PC/PCA/PG and TXAA for producing a medicament.

Country Status (13)

Country Link
EP (1) EP0268581B1 (en)
JP (1) JP2513656B2 (en)
AT (1) ATE74507T1 (en)
AU (1) AU602867B2 (en)
CA (1) CA1273577A (en)
DE (2) DE3526362A1 (en)
DK (1) DK169017B1 (en)
ES (1) ES2000090A6 (en)
GR (1) GR861862B (en)
IE (1) IE59338B1 (en)
IL (1) IL79452A0 (en)
WO (1) WO1987000434A1 (en)
ZA (1) ZA865395B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3717337A1 (en) * 1987-05-22 1988-12-15 Hoechst Ag METHOD FOR DETECTING THE ANTIAGGREGATORY EFFECT OF VASOACTIVE SUBSTANCES, SPECIFICALLY OF PHOSPHODIESTERASE AND / OR CYCLOOXYGENASE INHIBITORS
AT393962B (en) * 1987-10-22 1992-01-10 Thomae Gmbh Dr K Synergistic pharmaceutical combination with a content of a phosphodiesterase inhibitor and the use thereof
US4808627A (en) * 1987-12-16 1989-02-28 E. R. Squibb & Sons, Inc. Method of preventing or treating toxemia in pregnancy using a thromboxane A2 receptor antagonist
US4820733A (en) * 1988-03-07 1989-04-11 E.R. Squibb & Sons, Inc. Method of preventing or reducing platelet loss during extracorporeal circulation using a thromboxane A2 receptor antagonist
USH1139H (en) * 1988-07-21 1993-02-02 E. R. Squibb & Sons, Inc. Combination of a calcium channel blocker and thromboxane A2 receptor antagonist or synthetase inhibitor and method for treating ischemia employing such combination

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1595056A (en) * 1976-10-12 1981-08-05 Wellcome Found Pharmaceutical combination
JPS542335A (en) * 1977-05-20 1979-01-09 Wellcome Found Medical composition
CH637298A5 (en) * 1978-01-01 1983-07-29 Wellcome Found Combination preparation counteracting the aggregation of blood platelets
HU191110B (en) * 1982-10-01 1987-01-28 Farmitala Carlo Erba Spa,It Process for the production of the 15-cycloaliphatic derivatives 13,14-didehydro-carbaprostacyclines
US4456615A (en) * 1982-10-25 1984-06-26 E. R. Squibb & Sons, Inc. 7-Oxabicycloheptane substituted amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction
US4499296A (en) * 1983-11-14 1985-02-12 G. D. Searle & Co. Omega cycloalkyl prostaglandins
US4579958A (en) * 1983-12-23 1986-04-01 G. D. Searle & Co. 5-fluoro-3-oxa-6,7-didehydro-PGI1 compounds

Also Published As

Publication number Publication date
JPS63501360A (en) 1988-05-26
DE3526362A1 (en) 1987-01-22
ATE74507T1 (en) 1992-04-15
AU5993386A (en) 1987-02-10
IE861923L (en) 1987-01-19
AU602867B2 (en) 1990-11-01
ES2000090A6 (en) 1987-12-01
ZA865395B (en) 1987-03-25
IE59338B1 (en) 1994-02-09
IL79452A0 (en) 1986-10-31
CA1273577A (en) 1990-09-04
JP2513656B2 (en) 1996-07-03
EP0268581B1 (en) 1992-04-08
DK136887D0 (en) 1987-03-17
GR861862B (en) 1986-11-17
DK169017B1 (en) 1994-08-01
DE3684785D1 (en) 1992-05-14
EP0268581A1 (en) 1988-06-01
WO1987000434A1 (en) 1987-01-29

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Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed