DK133083A - METHOD OF PREPARING PHENYLALKYLOXIRANCARBOXYL ACID - Google Patents

METHOD OF PREPARING PHENYLALKYLOXIRANCARBOXYL ACID Download PDF

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Publication number
DK133083A
DK133083A DK133083A DK133083A DK133083A DK 133083 A DK133083 A DK 133083A DK 133083 A DK133083 A DK 133083A DK 133083 A DK133083 A DK 133083A DK 133083 A DK133083 A DK 133083A
Authority
DK
Denmark
Prior art keywords
group
denotes
lower alkyl
alkyl group
phenylalkyloxirancarboxyl
Prior art date
Application number
DK133083A
Other languages
Danish (da)
Other versions
DK133083D0 (en
Inventor
Bernhard Kohl
Klaus Eistetter
Hermann Amschler
Gerhard Ludwig
Horst Wolf
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Publication of DK133083A publication Critical patent/DK133083A/en
Publication of DK133083D0 publication Critical patent/DK133083D0/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/48Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Epoxy Compounds (AREA)
  • Pyrane Compounds (AREA)

Abstract

Phenylalkyloxirane carboxylic acids of the general formula I <IMAGE> wherein R<1> denotes a hydrogen atom, a halogen atom, a lower alkyl group, a lower alkoxy group or a trifluoromethyl group, R<2> has one of the meanings of R<1>, A denotes a single bond, a -CH(R<6>)-CH(R<7>)-group, a CH(R<6>)-CH(R<7>)-CH(R<8>)-group or a -CH(R<6>)-CH(R<7>)-CH(R<8>)-CH(R<9>)-group, R<5> denotes a hydrogen atom or a lower alkyl group and one of the substituents R<3>, R<4>, R<6>, R<7>, R<8> or R<9> represents a lower alkyl group and the others denote hydrogen atoms, and the salts of the carboxylic acids are new compounds having a hypoglycaemic action. A process for their preparation and a new process for the preparation of the intermediate products is described.
DK1330/83A 1981-07-24 1983-03-23 METHOD OF PREPARING PHENYLALKYLOXIRANCARBOXYL ACID DK133083D0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH483881 1981-07-24
PCT/EP1982/000156 WO1983000334A1 (en) 1981-07-24 1982-07-21 Phenylalkyloxirane carboxylic acids, preparation and therapeutical use

Publications (2)

Publication Number Publication Date
DK133083A true DK133083A (en) 1983-03-23
DK133083D0 DK133083D0 (en) 1983-03-23

Family

ID=4283438

Family Applications (1)

Application Number Title Priority Date Filing Date
DK1330/83A DK133083D0 (en) 1981-07-24 1983-03-23 METHOD OF PREPARING PHENYLALKYLOXIRANCARBOXYL ACID

Country Status (11)

Country Link
EP (1) EP0071175B1 (en)
JP (1) JPS58501124A (en)
AT (1) ATE18556T1 (en)
DE (1) DE3269811D1 (en)
DK (1) DK133083D0 (en)
ES (1) ES8307780A1 (en)
GR (1) GR76871B (en)
IL (1) IL66365A0 (en)
PT (1) PT75311B (en)
WO (1) WO1983000334A1 (en)
ZA (1) ZA825291B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1259827A (en) * 1984-07-17 1989-09-26 Mitsumasa Kurosawa Cold-rolled steel sheets and a method of manufacturing the same
WO1987000751A2 (en) * 1985-08-02 1987-02-12 Byk Gulden Lomberg Chemische Fabrik Gmbh Use of oxirancarboxylic acids for the treatment of hyperlipemia
EP0283168A3 (en) * 1987-03-16 1989-06-14 American Home Products Corporation Fluorooxirane carboxylates
DE19705718A1 (en) 1997-02-14 1998-08-20 Horst P O Dr Wolf New oxirane carboxylic acids to treat type 2 diabetes and other insulin resistant conditions
CN111613407B (en) * 2020-06-03 2022-05-03 福建省长汀金龙稀土有限公司 R-T-B series permanent magnet material, raw material composition, preparation method and application thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0025192B1 (en) * 1979-09-07 1983-05-11 Byk Gulden Lomberg Chemische Fabrik GmbH Substituted oxirane carboxylic acids, process for their preparation, their use and medicines containing them

Also Published As

Publication number Publication date
ES514235A0 (en) 1983-08-01
GR76871B (en) 1984-09-04
ES8307780A1 (en) 1983-08-01
ATE18556T1 (en) 1986-03-15
PT75311B (en) 1985-01-11
WO1983000334A1 (en) 1983-02-03
JPS58501124A (en) 1983-07-14
EP0071175A2 (en) 1983-02-09
EP0071175A3 (en) 1983-04-13
EP0071175B1 (en) 1986-03-12
ZA825291B (en) 1983-05-25
DK133083D0 (en) 1983-03-23
DE3269811D1 (en) 1986-04-17
IL66365A0 (en) 1982-11-30
PT75311A (en) 1982-08-01

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Legal Events

Date Code Title Description
PBP Patent lapsed
AHB Application shelved due to non-payment
AHB Application shelved due to non-payment