DK131087A - 1,2,3,4-tetrahydro-6-substitueret-4-aryl-(eller -heterocyclo-)-3-substitueret-2-thioxo-/eller -oxo)-5-pyrimidincarboxylsyrer og estere - Google Patents
1,2,3,4-tetrahydro-6-substitueret-4-aryl-(eller -heterocyclo-)-3-substitueret-2-thioxo-/eller -oxo)-5-pyrimidincarboxylsyrer og estereInfo
- Publication number
- DK131087A DK131087A DK131087A DK131087A DK131087A DK 131087 A DK131087 A DK 131087A DK 131087 A DK131087 A DK 131087A DK 131087 A DK131087 A DK 131087A DK 131087 A DK131087 A DK 131087A
- Authority
- DK
- Denmark
- Prior art keywords
- substituted
- pyrimidincarboxylic
- heterocyclo
- thioxo
- tetrahydro
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/20—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D239/22—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/839,770 US4684655A (en) | 1986-03-14 | 1986-03-14 | 1,2,3,4-tetrahydro-6-substituted-4-aryl-3-substituted-2-thioxo(or oxo)-5-pyrimidinecarboxylic acids and esters and use thereof to lower blood pressure |
US06/840,130 US4684656A (en) | 1986-03-14 | 1986-03-14 | 1,2,3,4-tetrahydro-6-substituted-4-aryl-3-(substituted sulfonyl)-2-thioxo(or oxo)-5-pyrimidinecarboxylic acids and esters and method of using them to lower blood pressure |
Publications (2)
Publication Number | Publication Date |
---|---|
DK131087D0 DK131087D0 (da) | 1987-03-13 |
DK131087A true DK131087A (da) | 1987-09-15 |
Family
ID=27126139
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK131087A DK131087A (da) | 1986-03-14 | 1987-03-13 | 1,2,3,4-tetrahydro-6-substitueret-4-aryl-(eller -heterocyclo-)-3-substitueret-2-thioxo-/eller -oxo)-5-pyrimidincarboxylsyrer og estere |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0236902B1 (da) |
AU (1) | AU598793B2 (da) |
CA (1) | CA1275410C (da) |
DE (1) | DE3766514D1 (da) |
DK (1) | DK131087A (da) |
HU (1) | HUT43831A (da) |
NZ (1) | NZ219299A (da) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL81800A0 (en) * | 1986-03-14 | 1987-10-20 | Squibb & Sons Inc | 1,2,3,4-tetrahydro-6-substituted-4-aryl(or heterocyclo)-3-((substituted amino)carbonyl)-2-thioxo(or oxo)-5-pyrimidine-carboxylic acids and esters and pharmaceutical compositions containing the same |
US6268369B1 (en) | 1994-11-16 | 2001-07-31 | Synaptic Pharmaceutical Corporation | 5-(heterocyclic alkyl)-6-aryl-dihydropyrimidines |
MX9703518A (es) * | 1994-11-16 | 1997-08-30 | Synaptic Pharma Corp | Dihidropirimidinas y usos de las mismas. |
US6228861B1 (en) | 1995-11-16 | 2001-05-08 | Synaptic Pharmaceutical Corporation | Dihydropyrimidines and uses thereof |
US6172066B1 (en) | 1996-05-16 | 2001-01-09 | Synaptic Pharmaceutical Corporation | Dihydropyrimidines and uses thereof |
US6245773B1 (en) | 1996-05-16 | 2001-06-12 | Synaptic Pharmaceutical Corporation | 5-(heterocyclic alkyl)-6-aryl-dihydropyrimidines |
US6080760A (en) * | 1997-06-18 | 2000-06-27 | Merck & Co., Inc. | Alpha 1A adrenergic receptor antagonists |
US6057350A (en) * | 1997-06-18 | 2000-05-02 | Merck & Co., Inc. | Alpha 1a adrenergic receptor antagonists |
US6037354A (en) * | 1997-06-18 | 2000-03-14 | Merck & Co., Inc. | Alpha 1a adrenergic receptor antagonists |
US6214832B1 (en) | 1997-06-18 | 2001-04-10 | Merck & Co., Inc. | Bis-piperidinyl-pyrimidin-2-ones as alpha 1a adrenergic receptor antagonists |
US6143750A (en) * | 1997-06-18 | 2000-11-07 | Merck & Co., Inc. | Alpha 1a adrenergic receptor antagonists |
US6376503B1 (en) | 1997-06-18 | 2002-04-23 | Merck & Co., Inc | Alpha 1a adrenergic receptor antagonists |
US6339099B1 (en) | 1997-06-20 | 2002-01-15 | Dupont Pharmaceuticals Company | Guanidine mimics as factor Xa inhibitors |
US6680323B2 (en) | 1998-12-23 | 2004-01-20 | Synaptic Pharmaceutical Corporation | Dihydropyrimidines and uses thereof |
US6274585B1 (en) | 1998-12-23 | 2001-08-14 | Synaptic Pharmaceutical Corporation | Dihydropyrimidines and uses thereof |
US6720324B2 (en) | 2000-07-05 | 2004-04-13 | Synaptic Pharmaceutical Corporation | Selective melanin concentrating hormone-1 (MCH1) receptor antagonists and uses thereof |
US7166603B2 (en) | 2003-07-23 | 2007-01-23 | Bristol-Myers Squibb Co. | Dihydropyrimidone inhibitors of calcium channel function |
US7157461B2 (en) | 2003-07-23 | 2007-01-02 | Bristol-Myers Squibb Co. | Substituted dihydropyrimidine inhibitors of calcium channel function |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1561290A (en) * | 1975-10-16 | 1980-02-20 | Nyegaard & Co As | Pyrimid - 2 - ones |
US4041035A (en) * | 1976-06-08 | 1977-08-09 | Morton-Norwich Products, Inc. | 1-Benzyl-1,2-dihydro-3-methyl-2-oxopyrimidinium iodide |
US4609494A (en) * | 1985-02-21 | 1986-09-02 | Merck & Co., Inc. | 5-acetyl-3,4,5,6-tetrahydro-4-oxo-2,6-methano-2H-1,3,5-benzothiazocine(benzodiazocine)-11-carboxylates useful as calcium channel blockers |
-
1987
- 1987-02-17 NZ NZ21929987A patent/NZ219299A/xx unknown
- 1987-02-17 CA CA000529900A patent/CA1275410C/en not_active Expired - Fee Related
- 1987-02-26 AU AU69270/87A patent/AU598793B2/en not_active Ceased
- 1987-03-02 EP EP19870102922 patent/EP0236902B1/en not_active Expired
- 1987-03-02 DE DE8787102922T patent/DE3766514D1/de not_active Expired - Fee Related
- 1987-03-13 HU HU112487A patent/HUT43831A/hu unknown
- 1987-03-13 DK DK131087A patent/DK131087A/da not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0236902B1 (en) | 1990-12-05 |
DE3766514D1 (de) | 1991-01-17 |
CA1275410C (en) | 1990-10-23 |
HUT43831A (en) | 1987-12-28 |
DK131087D0 (da) | 1987-03-13 |
AU598793B2 (en) | 1990-07-05 |
AU6927087A (en) | 1987-09-17 |
EP0236902A1 (en) | 1987-09-16 |
NZ219299A (en) | 1989-01-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |