DK129434B - Process for the preparation of a pharmaceutical composition of acetylsalicylic acid as active substance as well as polysiloxane and a cellulose ether or ester and with gradual release of the active substance. - Google Patents

Process for the preparation of a pharmaceutical composition of acetylsalicylic acid as active substance as well as polysiloxane and a cellulose ether or ester and with gradual release of the active substance.

Info

Publication number
DK129434B
DK129434B DK487571AA DK487571A DK129434B DK 129434 B DK129434 B DK 129434B DK 487571A A DK487571A A DK 487571AA DK 487571 A DK487571 A DK 487571A DK 129434 B DK129434 B DK 129434B
Authority
DK
Denmark
Prior art keywords
active substance
polysiloxane
ester
preparation
pharmaceutical composition
Prior art date
Application number
DK487571AA
Other languages
Danish (da)
Other versions
DK129434C (en
Inventor
S Casadio
E Sclavi
R Perego
Original Assignee
Angeli Inst Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Angeli Inst Spa filed Critical Angeli Inst Spa
Publication of DK129434B publication Critical patent/DK129434B/en
Application granted granted Critical
Publication of DK129434C publication Critical patent/DK129434C/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/60—Salicylic acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
DK487571AA 1970-10-09 1971-10-07 Process for the preparation of a pharmaceutical composition of acetylsalicylic acid as active substance as well as polysiloxane and a cellulose ether or ester and with gradual release of the active substance. DK129434B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB4816770A GB1357737A (en) 1970-10-09 1970-10-09 Sustained release pharmaceutical compositions

Publications (2)

Publication Number Publication Date
DK129434B true DK129434B (en) 1974-10-14
DK129434C DK129434C (en) 1975-03-10

Family

ID=10447626

Family Applications (1)

Application Number Title Priority Date Filing Date
DK487571AA DK129434B (en) 1970-10-09 1971-10-07 Process for the preparation of a pharmaceutical composition of acetylsalicylic acid as active substance as well as polysiloxane and a cellulose ether or ester and with gradual release of the active substance.

Country Status (8)

Country Link
US (1) US3853988A (en)
CA (1) CA974883A (en)
DE (1) DE2149699A1 (en)
DK (1) DK129434B (en)
ES (1) ES395533A1 (en)
FR (1) FR2110314B1 (en)
GB (1) GB1357737A (en)
SE (1) SE382560B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS51123814A (en) * 1975-04-22 1976-10-28 Shin Etsu Chem Co Ltd A process for preparing gradually releasable solid medicines
US4167558A (en) 1976-02-13 1979-09-11 Hoffmann-La Roche Inc. Novel sustained release tablet formulations
DE2902414A1 (en) * 1979-01-23 1980-08-07 Hoechst Ag DEPOT BODY BASED ON SILICONE RUBBER AND METHOD FOR THE PRODUCTION THEREOF
FR2514261B1 (en) * 1981-10-08 1986-08-22 Aec Chim Organ Biolog NOVEL COMPOSITION FOR COATING FOODS AND DRUGS AND GRANULES THUS COATED
DE3508097A1 (en) * 1984-07-21 1986-02-06 Hoechst Ag, 6230 Frankfurt COMBINATION PRODUCT MADE OF XANTHINE DERIVATIVES AND O-ACETYLSALICYL ACID OR THEIR PHARMACOLOGICALLY COMPATIBLE SALTS AND THE USE THEREOF
FR2653338B1 (en) * 1989-10-23 1994-06-10 Dow Corning Sa FORMULATION FOR SUSTAINED RELEASE DRUGS AND THE USE THEREOF.
AU706351B2 (en) * 1994-03-18 1999-06-17 Alfred Schmidt The use of dimeticone as a transport and carrier system and/or drug delivery system
DE4409357C2 (en) * 1994-03-18 1996-10-17 Upmeyer Hans Juergen Use of Dimeticon to eradicate Heliobacter pylori
US5965161A (en) * 1994-11-04 1999-10-12 Euro-Celtique, S.A. Extruded multi-particulates
AU6403196A (en) 1995-06-30 1997-02-05 Baylor University Polyester/carboxylic acid composite materials
US20110039807A1 (en) * 2009-08-13 2011-02-17 Kim Hyoung-Chun Anti-parkinsonian compound acetylsalicylic acid maltol ester
CN104603194B (en) 2012-07-17 2017-11-24 陶氏环球技术有限责任公司 Composition comprising organic liquid diluent and low-viscosity cellulose ether

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2805977A (en) * 1955-01-04 1957-09-10 Smith Kline French Lab Sustained release pharmaceutical preparation
GB971486A (en) * 1960-04-01 1964-09-30 Rech S Pharma Et Scient Therapeutic compositions comprising aspirin and polysiloxanes
US3133863A (en) * 1961-03-10 1964-05-19 Strong Cobb Arner Inc Sustained release therapeutic tablet compositions comprising organic solvent-gelled gums
AU407324B2 (en) * 1962-05-01 1970-10-28 Smith, Kline & French Laboratories Powdered silicone products and processes
IL26885A (en) * 1965-12-06 1970-10-30 Smith Kline French Lab Pharmaceutical silicone compositions
US3518344A (en) * 1967-10-02 1970-06-30 Miles Lab Tableting lubricant

Also Published As

Publication number Publication date
GB1357737A (en) 1974-06-26
ES395533A1 (en) 1974-10-16
CA974883A (en) 1975-09-23
FR2110314A1 (en) 1972-06-02
DK129434C (en) 1975-03-10
US3853988A (en) 1974-12-10
DE2149699A1 (en) 1972-04-13
SE382560B (en) 1976-02-09
FR2110314B1 (en) 1975-06-06

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