DK1275376T3 - Biphasic hydrogels for use in eye drops - Google Patents

Biphasic hydrogels for use in eye drops

Info

Publication number
DK1275376T3
DK1275376T3 DK01124148T DK01124148T DK1275376T3 DK 1275376 T3 DK1275376 T3 DK 1275376T3 DK 01124148 T DK01124148 T DK 01124148T DK 01124148 T DK01124148 T DK 01124148T DK 1275376 T3 DK1275376 T3 DK 1275376T3
Authority
DK
Denmark
Prior art keywords
biphasic
hydrogels
eye drops
eye
droppable
Prior art date
Application number
DK01124148T
Other languages
Danish (da)
Inventor
Piroska Kreitmeier
Monika Muggenthaler
Heinz Dr Polzer
Original Assignee
Medproject Pharma Entwicklungs
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medproject Pharma Entwicklungs filed Critical Medproject Pharma Entwicklungs
Application granted granted Critical
Publication of DK1275376T3 publication Critical patent/DK1275376T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/12—Cyclic peptides, e.g. bacitracins; Polymyxins; Gramicidins S, C; Tyrocidins A, B or C
    • A61K38/13—Cyclosporins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Preparation (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A droppable gel-emulsion (A), especially for use in the eye, contains a polymer mixture of polyacrylate (I) with polyvinyl alcohol, polyvinyl pyrrolidone, dextran or a cellulose derivative (II). An Independent claim is also included for the preparation of (A).
DK01124148T 2001-07-06 2001-10-10 Biphasic hydrogels for use in eye drops DK1275376T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10132876A DE10132876A1 (en) 2001-07-06 2001-07-06 Two-phase, drop-onable hydrogels for use on the eye

Publications (1)

Publication Number Publication Date
DK1275376T3 true DK1275376T3 (en) 2006-08-28

Family

ID=7690886

Family Applications (1)

Application Number Title Priority Date Filing Date
DK01124148T DK1275376T3 (en) 2001-07-06 2001-10-10 Biphasic hydrogels for use in eye drops

Country Status (9)

Country Link
EP (1) EP1275376B1 (en)
AT (1) ATE323469T1 (en)
CY (1) CY1105090T1 (en)
DE (2) DE10132876A1 (en)
DK (1) DK1275376T3 (en)
ES (1) ES2262592T3 (en)
HK (1) HK1052873B (en)
PT (1) PT1275376E (en)
SI (1) SI1275376T1 (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005035879A1 (en) * 2005-07-30 2007-02-01 Paul Hartmann Ag Hydrogel useful as a wound filler or dressing comprises a gel-forming polysaccharide, an acrylic acid derivative and an electrolyte mixture
DE102006049091A1 (en) * 2006-10-18 2008-04-24 Dr. Gerhard Mann Chem.-Pharm. Fabrik Gmbh Emulsifier-free ophthalmic preparation containing vegetable oil
FR2916636B1 (en) † 2007-05-29 2009-09-04 Octalia Technologies VEHICLE IN THE FORM OF AN OIL-IN-WATER EMULSION PARTICULARLY FOR OPHTHALMIC OR DERMOCOSMETIC USE
CN102026665A (en) * 2008-05-19 2011-04-20 爱尔康研究有限公司 Pharmaceutical compositions having carboxyvinyl polymer and povidone polymer
KR20130094293A (en) * 2010-07-21 2013-08-23 알콘 리서치, 리미티드 Pharmaceutical composition with enhanced solubility characteristics
CN102525887A (en) * 2012-01-16 2012-07-04 无锡信仁堂药物技术有限公司 Cyclosporine-containing ophthalmic emulsion gel and preparation method thereof
EP3103439B1 (en) * 2015-06-09 2019-08-07 MEDproject Pharma-Entwicklungs- und Vertriebsgesellschaft mbH Drippable ophthalmic bimatoprost gel
US20220378698A1 (en) * 2019-07-12 2022-12-01 Pharmathen S.A. Preservative free pharmaceutical composition for ophthalmic administration containing cyclosporine
CN113786380A (en) * 2021-09-18 2021-12-14 华北制药股份有限公司 Pilocarpine nitrate ophthalmic gel and preparation method thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5252318A (en) * 1990-06-15 1993-10-12 Allergan, Inc. Reversible gelation compositions and methods of use
US5296228A (en) * 1992-03-13 1994-03-22 Allergan, Inc. Compositions for controlled delivery of pharmaceutical compounds
DE4209722C3 (en) * 1992-03-25 1997-06-19 Medproject Pharma Entwicklungs Dripable gel for ophthalmology
DE19511322C2 (en) * 1995-03-28 1999-09-02 Mann Gerhard Chem Pharm Fab Sterile eye gels containing medium chain triglycerides and process for their preparation
DE19614823A1 (en) * 1996-04-15 1997-10-16 Mann Gerhard Chem Pharm Fab Ophthalmic composition with prolonged retention time on the eye
IN185228B (en) * 1999-02-03 2000-12-09 Bakulesh Mafatlal Dr Khamar

Also Published As

Publication number Publication date
DE10132876A1 (en) 2003-01-30
DE50109549D1 (en) 2006-05-24
HK1052873A1 (en) 2003-10-03
EP1275376A2 (en) 2003-01-15
SI1275376T1 (en) 2006-08-31
EP1275376B1 (en) 2006-04-19
EP1275376A3 (en) 2003-04-16
CY1105090T1 (en) 2010-03-03
HK1052873B (en) 2006-09-08
PT1275376E (en) 2006-07-31
ATE323469T1 (en) 2006-05-15
ES2262592T3 (en) 2006-12-01

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