DK1263503T3 - The use of cyanoquinolines for treatment involves inhibition of colon polyps - Google Patents
The use of cyanoquinolines for treatment involves inhibition of colon polypsInfo
- Publication number
- DK1263503T3 DK1263503T3 DK01918367T DK01918367T DK1263503T3 DK 1263503 T3 DK1263503 T3 DK 1263503T3 DK 01918367 T DK01918367 T DK 01918367T DK 01918367 T DK01918367 T DK 01918367T DK 1263503 T3 DK1263503 T3 DK 1263503T3
- Authority
- DK
- Denmark
- Prior art keywords
- cyanoquinolines
- treatment involves
- colon polyps
- involves inhibition
- inhibition
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4706—4-Aminoquinolines; 8-Aminoquinolines, e.g. chloroquine, primaquine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4741—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran derivatives, noscapine, bicuculline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/582—Recycling of unreacted starting or intermediate materials
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US52419600A | 2000-03-13 | 2000-03-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1263503T3 true DK1263503T3 (en) | 2006-02-13 |
Family
ID=24088181
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK01918367T DK1263503T3 (en) | 2000-03-13 | 2001-03-06 | The use of cyanoquinolines for treatment involves inhibition of colon polyps |
Country Status (23)
| Country | Link |
|---|---|
| EP (1) | EP1263503B1 (en) |
| JP (1) | JP2003526686A (en) |
| KR (2) | KR100817423B1 (en) |
| CN (1) | CN1190197C (en) |
| AR (1) | AR035482A1 (en) |
| AT (1) | ATE308364T1 (en) |
| AU (2) | AU4545201A (en) |
| BR (1) | BR0109165A (en) |
| CA (1) | CA2402742C (en) |
| DE (1) | DE60114580T2 (en) |
| DK (1) | DK1263503T3 (en) |
| EA (1) | EA200200976A1 (en) |
| ES (1) | ES2248302T3 (en) |
| HK (1) | HK1048775B (en) |
| HU (1) | HUP0300547A2 (en) |
| IL (2) | IL151249A0 (en) |
| MX (1) | MXPA02008836A (en) |
| NO (1) | NO20024356L (en) |
| NZ (1) | NZ521117A (en) |
| PL (1) | PL202873B1 (en) |
| TW (1) | TWI262805B (en) |
| WO (1) | WO2001068186A2 (en) |
| ZA (1) | ZA200208178B (en) |
Families Citing this family (47)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6576644B2 (en) | 2000-09-06 | 2003-06-10 | Bristol-Myers Squibb Co. | Quinoline inhibitors of cGMP phosphodiesterase |
| US7019012B2 (en) | 2000-12-20 | 2006-03-28 | Boehringer Ingelheim International Pharma Gmbh & Co. Kg | Quinazoline derivatives and pharmaceutical compositions containing them |
| CA2468015A1 (en) | 2001-11-27 | 2003-06-05 | Merck & Co., Inc. | 2-aminoquinoline compounds |
| EP1477481B1 (en) * | 2002-01-28 | 2009-07-22 | Ube Industries, Ltd. | Process for producing quinazolin-4-one derivative |
| BR0307375A (en) | 2002-02-05 | 2004-12-07 | Wyeth Corp | Process for the synthesis of n-acyl-2-amino-4-alkoxy-5-nitro-benzoic acids |
| US7009053B2 (en) * | 2002-04-30 | 2006-03-07 | Yungjin Pharmaceuticals Co., Ltd. | Quinoline derivatives as caspase-3 inhibitor, preparation for producing the same and pharmaceutical composition comprising the same |
| DE10221018A1 (en) | 2002-05-11 | 2003-11-27 | Boehringer Ingelheim Pharma | Use of inhibitors of EGFR-mediated signal transduction for the treatment of benign prostatic hyperplasia (BPH) / prostatic hypertrophy |
| CA2491191C (en) | 2002-07-15 | 2014-02-04 | Exelixis, Inc. | Receptor-type kinase modulators and methods of use |
| US7109337B2 (en) | 2002-12-20 | 2006-09-19 | Pfizer Inc | Pyrimidine derivatives for the treatment of abnormal cell growth |
| PT1625121E (en) | 2002-12-20 | 2010-03-11 | Pfizer Prod Inc | Pyrimidine derivatives for the treatment of abnormal cell growth |
| WO2006074147A2 (en) | 2005-01-03 | 2006-07-13 | Myriad Genetics, Inc. | Nitrogen containing bicyclic compounds and therapeutical use thereof |
| US8309562B2 (en) | 2003-07-03 | 2012-11-13 | Myrexis, Inc. | Compounds and therapeutical use thereof |
| ATE517091T1 (en) | 2003-09-26 | 2011-08-15 | Exelixis Inc | C-MET MODULATORS AND METHODS OF USE |
| TW200529846A (en) | 2004-02-20 | 2005-09-16 | Wyeth Corp | 3-quinolinecarbonitrile protein kinase inhibitors |
| BRPI0510980A (en) | 2004-05-14 | 2007-11-27 | Pfizer Prod Inc | pyrimidine derivatives for the treatment of abnormal cell growth |
| CA2564199A1 (en) | 2004-05-14 | 2005-11-24 | Pfizer Products Inc. | Pyrimidine derivatives for the treatment of abnormal cell growth |
| MXPA06011658A (en) | 2004-05-14 | 2006-12-14 | Pfizer Prod Inc | Pyrimidine derivatives for the treatment of abnormal cell growth. |
| US8258145B2 (en) | 2005-01-03 | 2012-09-04 | Myrexis, Inc. | Method of treating brain cancer |
| CA2608589A1 (en) * | 2005-05-25 | 2006-11-30 | Wyeth | Methods of synthesizing 6-alkylaminoquinoline derivatives |
| EP1948179A1 (en) | 2005-11-11 | 2008-07-30 | Boehringer Ingelheim International GmbH | Quinazoline derivatives for the treatment of cancer diseases |
| DE102006029445A1 (en) * | 2006-06-21 | 2007-12-27 | Bayer Schering Pharma Ag | New 3-cyano-quinolines as kinase inhibitors |
| DE102006029446A1 (en) * | 2006-06-21 | 2007-12-27 | Bayer Schering Pharma Ag | New 3-substituted quinolines as kinase inhibitors |
| SI2068880T1 (en) | 2006-09-18 | 2012-08-31 | Boehringer Ingelheim Int | Method for treating cancer harboring egfr mutations |
| DE102007024470A1 (en) | 2007-05-24 | 2008-11-27 | Bayer Schering Pharma Aktiengesellschaft | New sulfoximine-substituted quinoline and/or quinazoline derivatives are erythropoietin-producing hepatoma amplified sequence-receptor kinase inhibitors useful to prepare medicaments to e.g. treat endometriosis and stenosis |
| EP2072502A1 (en) | 2007-12-20 | 2009-06-24 | Bayer Schering Pharma Aktiengesellschaft | Sulfoximide substituted chinolin and chinazolin derivatives as kinase inhibitors |
| TW202241853A (en) | 2009-01-16 | 2022-11-01 | 美商艾克塞里克斯公司 | Pharmaceutical composition comprising malate salt of n-(4-{[6,7-bis(methyloxy)quinolin-4-yl]oxy}phenyl)-n'-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide and use thereof |
| UY32742A (en) | 2009-06-25 | 2010-12-31 | Amgen Inc | HETEROCYCLIC COMPOUNDS AND THEIR USES |
| HUE044629T2 (en) | 2009-07-06 | 2019-11-28 | Boehringer Ingelheim Int | Process for drying of bibw2992, of its salts and of solid pharmaceutical formulations comprising this active ingredient |
| UA108618C2 (en) | 2009-08-07 | 2015-05-25 | APPLICATION OF C-MET-MODULATORS IN COMBINATION WITH THEMOSOLOMID AND / OR RADIATION THERAPY FOR CANCER TREATMENT | |
| AU2010363329A1 (en) | 2010-11-07 | 2013-05-09 | Targegen, Inc. | Compositions and methods for treating myelofibrosis |
| TWI659021B (en) | 2013-10-10 | 2019-05-11 | 亞瑞克西斯製藥公司 | Inhibitors of kras g12c |
| US9242965B2 (en) | 2013-12-31 | 2016-01-26 | Boehringer Ingelheim International Gmbh | Process for the manufacture of (E)-4-N,N-dialkylamino crotonic acid in HX salt form and use thereof for synthesis of EGFR tyrosine kinase inhibitors |
| JP6533997B2 (en) * | 2014-12-26 | 2019-06-26 | 株式会社ヤクルト本社 | Compound having ZNF143 inhibitory activity and use thereof |
| KR20180005178A (en) * | 2015-04-10 | 2018-01-15 | 아락세스 파마 엘엘씨 | Substituted quinazoline compounds and methods for their use |
| US10858343B2 (en) | 2015-09-28 | 2020-12-08 | Araxes Pharma Llc | Inhibitors of KRAS G12C mutant proteins |
| EP3356339A1 (en) | 2015-09-28 | 2018-08-08 | Araxes Pharma LLC | Inhibitors of kras g12c mutant proteins |
| EP3356347A1 (en) | 2015-09-28 | 2018-08-08 | Araxes Pharma LLC | Inhibitors of kras g12c mutant proteins |
| EP3356354A1 (en) | 2015-09-28 | 2018-08-08 | Araxes Pharma LLC | Inhibitors of kras g12c mutant proteins |
| EP3377481A1 (en) | 2015-11-16 | 2018-09-26 | Araxes Pharma LLC | 2-substituted quinazoline compounds comprising a substituted heterocyclic group and methods of use thereof |
| JP7327802B2 (en) | 2017-01-26 | 2023-08-16 | アラクセス ファーマ エルエルシー | Fused hetero-heterobicyclic compounds and methods of use thereof |
| WO2018140512A1 (en) | 2017-01-26 | 2018-08-02 | Araxes Pharma Llc | Fused bicyclic benzoheteroaromatic compounds and methods of use thereof |
| US11136308B2 (en) | 2017-01-26 | 2021-10-05 | Araxes Pharma Llc | Substituted quinazoline and quinazolinone compounds and methods of use thereof |
| EP3573971A1 (en) | 2017-01-26 | 2019-12-04 | Araxes Pharma LLC | 1-(3-(6-(3-hydroxynaphthalen-1-yl)benzofuran-2-yl)azetidin-1yl)prop-2-en-1-one derivatives and similar compounds as kras g12c modulators for treating cancer |
| US11358959B2 (en) | 2017-01-26 | 2022-06-14 | Araxes Pharma Llc | Benzothiophene and benzothiazole compounds and methods of use thereof |
| CN110831933A (en) | 2017-05-25 | 2020-02-21 | 亚瑞克西斯制药公司 | Quinazoline derivatives as modulators of mutated KRAS, HRAS or NRAS |
| SG10202113146UA (en) | 2017-05-25 | 2021-12-30 | Araxes Pharma Llc | Covalent inhibitors of kras |
| JP2020521741A (en) | 2017-05-25 | 2020-07-27 | アラクセス ファーマ エルエルシー | Compounds for the treatment of cancer and methods of their use |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6002008A (en) * | 1997-04-03 | 1999-12-14 | American Cyanamid Company | Substituted 3-cyano quinolines |
| UA73073C2 (en) * | 1997-04-03 | 2005-06-15 | Уайт Холдінгз Корпорейшн | Substituted 3-cyan chinolines |
| AU783116B2 (en) * | 1999-08-12 | 2005-09-29 | Wyeth Holdings Corporation | NSAID and EFGR kinase inhibitor containing composition for the treatment or inhibition of colonic polyps and colorectal cancer |
-
2001
- 2001-03-06 HU HU0300547A patent/HUP0300547A2/en unknown
- 2001-03-06 DK DK01918367T patent/DK1263503T3/en active
- 2001-03-06 IL IL15124901A patent/IL151249A0/en active IP Right Grant
- 2001-03-06 CN CNB018093981A patent/CN1190197C/en not_active Expired - Fee Related
- 2001-03-06 DE DE60114580T patent/DE60114580T2/en not_active Expired - Lifetime
- 2001-03-06 PL PL363072A patent/PL202873B1/en not_active IP Right Cessation
- 2001-03-06 CA CA002402742A patent/CA2402742C/en not_active Expired - Fee Related
- 2001-03-06 KR KR1020027012074A patent/KR100817423B1/en not_active IP Right Cessation
- 2001-03-06 EP EP01918367A patent/EP1263503B1/en not_active Expired - Lifetime
- 2001-03-06 WO PCT/US2001/007068 patent/WO2001068186A2/en active IP Right Grant
- 2001-03-06 BR BR0109165-4A patent/BR0109165A/en not_active Application Discontinuation
- 2001-03-06 JP JP2001566747A patent/JP2003526686A/en not_active Withdrawn
- 2001-03-06 KR KR1020077027115A patent/KR20080009294A/en not_active Application Discontinuation
- 2001-03-06 NZ NZ521117A patent/NZ521117A/en unknown
- 2001-03-06 AT AT01918367T patent/ATE308364T1/en not_active IP Right Cessation
- 2001-03-06 EA EA200200976A patent/EA200200976A1/en unknown
- 2001-03-06 MX MXPA02008836A patent/MXPA02008836A/en active IP Right Grant
- 2001-03-06 AU AU4545201A patent/AU4545201A/en active Pending
- 2001-03-06 AU AU2001245452A patent/AU2001245452B2/en not_active Ceased
- 2001-03-06 ES ES01918367T patent/ES2248302T3/en not_active Expired - Lifetime
- 2001-03-12 TW TW090105702A patent/TWI262805B/en active
- 2001-03-12 AR ARP010101143A patent/AR035482A1/en not_active Application Discontinuation
-
2002
- 2002-08-14 IL IL151249A patent/IL151249A/en not_active IP Right Cessation
- 2002-09-12 NO NO20024356A patent/NO20024356L/en unknown
- 2002-10-10 ZA ZA200208178A patent/ZA200208178B/en unknown
-
2003
- 2003-02-13 HK HK03101049.6A patent/HK1048775B/en not_active IP Right Cessation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK1263503T3 (en) | The use of cyanoquinolines for treatment involves inhibition of colon polyps | |
| DK1259512T3 (en) | Pteridine compounds for the treatment of psoreasis | |
| DK1343773T3 (en) | Thiazole derivatives for the treatment of PPAR-related disorders | |
| DK1144395T3 (en) | 2-amino-benzoxazinone derivatives for the treatment of obesity | |
| NO20030230D0 (en) | Treatment of iron sulphide deposits | |
| DK1294644T3 (en) | Water Treatment Compositions | |
| DK1063990T3 (en) | Use of Biochanine-Enriched Extract for the Treatment of Estrogen-Associated Disorders | |
| DK1562932T3 (en) | 4 tetrazolyl-4-phenylpiperidine derivatives for the treatment of pain | |
| DK1324970T3 (en) | Retinoids for the treatment of emphysema | |
| DK1282616T3 (en) | Hydroxyphenylpiperidin-4-ylidene methylbenzamide derivatives for the treatment of pain | |
| DK1392318T3 (en) | 15-keto-prostaglandins for the treatment of drug-induced constipation | |
| DK1176964T3 (en) | Use of ET743 for the treatment of cancer | |
| DK1206436T3 (en) | Retinoids for the treatment of emphysema | |
| DK1499730T3 (en) | Immunoconjugates for the treatment of tumors | |
| DK1344526T3 (en) | Means for the prevention / treatment of inflammatory respiratory disorders | |
| DK1197485T3 (en) | Cyclobutenedione dione derivatives for the treatment of artherosclerosis | |
| NO20026219L (en) | Compounds for the treatment of impaired fundic relaxation | |
| DK1350521T3 (en) | Immunotherapeutic combinations for the treatment of tumors | |
| DK1200114T3 (en) | PPAR delta inhibitors for the treatment of cardiovascular disease | |
| DK1268482T3 (en) | Pyranoindoles for the treatment of glaucoma | |
| DK1468996T3 (en) | Indole derivatives for the treatment of CNS diseases | |
| DK1200447T3 (en) | Oxazinocarbazoles for the treatment of CNS diseases | |
| FR2805983B3 (en) | SHOWER | |
| DK1468686T3 (en) | S-methyl-dihydro-ziprasidone for the treatment of psychiatric disorders | |
| DK1567524T3 (en) | Thia-epothilone derivatives for the treatment of cancer |