DK125786A - PEPTIDES AND PREPARATION THEREOF - Google Patents

PEPTIDES AND PREPARATION THEREOF Download PDF

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Publication number
DK125786A
DK125786A DK125786A DK125786A DK125786A DK 125786 A DK125786 A DK 125786A DK 125786 A DK125786 A DK 125786A DK 125786 A DK125786 A DK 125786A DK 125786 A DK125786 A DK 125786A
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DK
Denmark
Prior art keywords
human insulin
precursors
insulin
prepared
peptides
Prior art date
Application number
DK125786A
Other languages
Danish (da)
Other versions
DK125786D0 (en
DK158270B (en
DK158270C (en
Inventor
Lars Thim
Mogens Trier Hansen
Kjeld Norris
Original Assignee
Novo Industri As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DK129385A external-priority patent/DK129385A/en
Application filed by Novo Industri As filed Critical Novo Industri As
Priority to DK125786A priority Critical patent/DK158270C/en
Publication of DK125786D0 publication Critical patent/DK125786D0/en
Publication of DK125786A publication Critical patent/DK125786A/en
Publication of DK158270B publication Critical patent/DK158270B/en
Application granted granted Critical
Publication of DK158270C publication Critical patent/DK158270C/en

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  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Previously unknown human insulin precursors of the formula B-X-Y-A, where X and Y are both lysine or arginine, are prepared by culturing a yeast host which is transformed with a replicatable vector which is able to express, in yeast, a DNA sequence which encodes the human insulin precursor. Human insulin is prepared by recovering the insulin precursors from the culture medium and converting the insulin precursors into human insulin by means of enzymic treatment. <IMAGE>
DK125786A 1985-03-22 1986-03-19 METHOD FOR MANUFACTURING HUMAN INSULIN PRECURSORS AND HUMAN INSULIN AND DNA SEQUENCES AND PLASMIDS FOR USE IN THESE PROCEDURES DK158270C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DK125786A DK158270C (en) 1985-03-22 1986-03-19 METHOD FOR MANUFACTURING HUMAN INSULIN PRECURSORS AND HUMAN INSULIN AND DNA SEQUENCES AND PLASMIDS FOR USE IN THESE PROCEDURES

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DK129385A DK129385A (en) 1985-03-22 1985-03-22 PEPTIDES AND PREPARATION THEREOF
DK129385 1985-03-22
DK125786 1986-03-19
DK125786A DK158270C (en) 1985-03-22 1986-03-19 METHOD FOR MANUFACTURING HUMAN INSULIN PRECURSORS AND HUMAN INSULIN AND DNA SEQUENCES AND PLASMIDS FOR USE IN THESE PROCEDURES

Publications (4)

Publication Number Publication Date
DK125786D0 DK125786D0 (en) 1986-03-19
DK125786A true DK125786A (en) 1986-11-17
DK158270B DK158270B (en) 1990-04-23
DK158270C DK158270C (en) 1990-09-10

Family

ID=26065478

Family Applications (1)

Application Number Title Priority Date Filing Date
DK125786A DK158270C (en) 1985-03-22 1986-03-19 METHOD FOR MANUFACTURING HUMAN INSULIN PRECURSORS AND HUMAN INSULIN AND DNA SEQUENCES AND PLASMIDS FOR USE IN THESE PROCEDURES

Country Status (1)

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DK (1) DK158270C (en)

Also Published As

Publication number Publication date
DK125786D0 (en) 1986-03-19
DK158270B (en) 1990-04-23
DK158270C (en) 1990-09-10

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