DK1176193T3 - Hæmmere af virusinfektion, som angriber den n-terminale region af integrase - Google Patents

Hæmmere af virusinfektion, som angriber den n-terminale region af integrase

Info

Publication number
DK1176193T3
DK1176193T3 DK00917458.2T DK00917458T DK1176193T3 DK 1176193 T3 DK1176193 T3 DK 1176193T3 DK 00917458 T DK00917458 T DK 00917458T DK 1176193 T3 DK1176193 T3 DK 1176193T3
Authority
DK
Denmark
Prior art keywords
integrase
attacking
inhibitors
virus infection
terminal region
Prior art date
Application number
DK00917458.2T
Other languages
English (en)
Inventor
Mari Kannagi
Takao Masuda
Original Assignee
Japan Science & Tech Agency
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Science & Tech Agency filed Critical Japan Science & Tech Agency
Application granted granted Critical
Publication of DK1176193T3 publication Critical patent/DK1176193T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/702—Specific hybridization probes for retroviruses
    • C12Q1/703—Viruses associated with AIDS
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • AIDS & HIV (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK00917458.2T 1999-05-13 2000-04-25 Hæmmere af virusinfektion, som angriber den n-terminale region af integrase DK1176193T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13340299 1999-05-13
PCT/JP2000/002698 WO2000070035A1 (fr) 1999-05-13 2000-04-25 Inhibiteurs utilises dans le ciblage d'infections virales d'une region a extremite terminale n de l'integrase

Publications (1)

Publication Number Publication Date
DK1176193T3 true DK1176193T3 (da) 2012-09-10

Family

ID=15103920

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00917458.2T DK1176193T3 (da) 1999-05-13 2000-04-25 Hæmmere af virusinfektion, som angriber den n-terminale region af integrase

Country Status (8)

Country Link
US (1) US7276333B1 (da)
EP (1) EP1176193B1 (da)
JP (1) JP4562290B2 (da)
AU (1) AU780121B2 (da)
CA (1) CA2372456C (da)
DK (1) DK1176193T3 (da)
TW (1) TWI281497B (da)
WO (1) WO2000070035A1 (da)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080032944A1 (en) * 2004-08-24 2008-02-07 Kyoto University Target Nucleic Acid Of Retrovirus Integration
EP2408803A4 (en) * 2009-03-19 2012-07-11 Integratech Proteomics Llc VIRAL INTEGRASE INHIBITORS AND METHODS OF USE

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2126266C1 (ru) * 1992-09-09 1999-02-20 Амген Боулдер, Инк. Способ ингибирования ретровирусной инфекции (варианты), ингибитор протеазы, кодирующая его нуклеиновая кислота и способ рекомбинантного продуцирования серинового ингибитора
US5627023A (en) 1993-03-29 1997-05-06 Duke University Suppressor of HIV replication and transcription
US6815461B1 (en) * 1994-01-20 2004-11-09 The University Of North Carolina At Chapel Hill Method of inhibiting retroviral integrase
EP0980388A1 (en) * 1997-05-20 2000-02-23 YISSUM RESEARCH DEVELOPMENT COMPANY of the Hebrew University of Jerusalem Vif-derived hiv protease inhibitors

Also Published As

Publication number Publication date
CA2372456C (en) 2009-08-25
US7276333B1 (en) 2007-10-02
EP1176193B1 (en) 2012-05-30
AU3843100A (en) 2000-12-05
CA2372456A1 (en) 2000-11-23
AU780121B2 (en) 2005-03-03
EP1176193A1 (en) 2002-01-30
EP1176193A4 (en) 2003-02-05
JP4562290B2 (ja) 2010-10-13
TWI281497B (en) 2007-05-21
WO2000070035A1 (fr) 2000-11-23

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