DK11684A - Fremgangsmaade til udtrykkelse af et funktionelt polypeptid i streptomyces ved hjaelp af en rekombinant dna udtrykkelsesvektor - Google Patents

Fremgangsmaade til udtrykkelse af et funktionelt polypeptid i streptomyces ved hjaelp af en rekombinant dna udtrykkelsesvektor Download PDF

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Publication number
DK11684A
DK11684A DK11684A DK11684A DK11684A DK 11684 A DK11684 A DK 11684A DK 11684 A DK11684 A DK 11684A DK 11684 A DK11684 A DK 11684A DK 11684 A DK11684 A DK 11684A
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Prior art keywords
streptomycs
expressing
procedure
expression vector
recombinant dna
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DK11684A
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Danish (da)
English (en)
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DK11684D0 (da
Inventor
Steven Kovacevic
Jeffrey Tobin Fayerman
James Robert Miller
Mark Alan Richardson
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Lilly Co Eli
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Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of DK11684D0 publication Critical patent/DK11684D0/da
Publication of DK11684A publication Critical patent/DK11684A/da

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C12N15/76Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/886Streptomyces

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  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK11684A 1983-01-18 1984-01-11 Fremgangsmaade til udtrykkelse af et funktionelt polypeptid i streptomyces ved hjaelp af en rekombinant dna udtrykkelsesvektor DK11684A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/458,803 US4559300A (en) 1983-01-18 1983-01-18 Method for using an homologous bacillus promoter and associated natural or modified ribosome binding site-containing DNA sequence in streptomyces

Publications (2)

Publication Number Publication Date
DK11684D0 DK11684D0 (da) 1984-01-11
DK11684A true DK11684A (da) 1984-07-19

Family

ID=23822145

Family Applications (1)

Application Number Title Priority Date Filing Date
DK11684A DK11684A (da) 1983-01-18 1984-01-11 Fremgangsmaade til udtrykkelse af et funktionelt polypeptid i streptomyces ved hjaelp af en rekombinant dna udtrykkelsesvektor

Country Status (11)

Country Link
US (1) US4559300A (cs)
EP (1) EP0117041B1 (cs)
JP (1) JPS59203491A (cs)
AU (1) AU2324084A (cs)
CA (1) CA1227150A (cs)
DE (1) DE3482045D1 (cs)
DK (1) DK11684A (cs)
FI (1) FI840105L (cs)
GB (1) GB2133798B (cs)
GR (1) GR81702B (cs)
IL (1) IL70661A (cs)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4663285A (en) * 1981-01-06 1987-05-05 The Public Health Laboratory Service Board Chimeric plasmids
US4503155A (en) * 1982-02-01 1985-03-05 Eli Lilly And Company Multifunctional, cloning vectors for use in Streptomyces, Bacillus, and E. coli
US4783405A (en) * 1983-01-18 1988-11-08 Eli Lilly And Company Recombinant DNA expression vectors useful in bacillus and other host cells
JPS60137291A (ja) * 1983-12-26 1985-07-20 Takeda Chem Ind Ltd 発現ベクター
EP0154539A3 (en) * 1984-03-06 1986-12-30 Eli Lilly And Company Recombinant dna expression vectors and method for gene expression
IL71555A (en) * 1984-04-15 1992-06-21 State Of Israel Israel Inst Fo Bovine interferon
US5126252A (en) * 1984-08-27 1992-06-30 Bio-Technology General Corp. Expressions vectors containing Lambda PL promoter and T1 T2 RNA termination sequence, plasmids containing the vectors, hosts containing the plasmids and relatedmethods
US5081020A (en) * 1984-08-27 1992-01-14 Bio-Technology General Corp. Expression vectors containing λPL promoter, T1 T2 rRNA termination sequence and origin of replication derived from a constitutive high copy number plasmid hosts and related methods
US5112744A (en) * 1984-08-27 1992-05-12 Bio-Technology General Corp. Plasmids for the production of human Cu-Zn superoxide dismutase, bacterial hosts containing the plasmids and methods for production and recovery of such superoxide dismutase
US5759816A (en) * 1984-08-27 1998-06-02 Bio-Technology General Corp. Expression vectors containing λPL promoter and T1 T2 rRNA termination sequence plasmids containing the vectors hosts containing the plasmids and related methods
US4766066A (en) * 1984-09-27 1988-08-23 Eli Lilly And Company Method of using bacteriophage lambda p1 promoter to produce a functional polypeptide in streptomyces
US4774180A (en) * 1986-02-26 1988-09-27 Massachusetts Institute Of Technology Construction and application of polyproteins
WO1986005812A1 (en) * 1985-03-29 1986-10-09 Biotechnica International, Inc. Secretion vector
US4977089A (en) * 1987-01-30 1990-12-11 Eli Lilly And Company Vector comprising signal peptide-encoding DNA for use in Bacillus and other microorganisms
WO1990010069A1 (en) * 1989-02-28 1990-09-07 Institut Organicheskogo Sinteza Akademii Nauk Latviiskoi Ssr RECOMBINANT PLASMID DNA pAA 1213-23 AND pAC 262-33 CODING FOR SYNTHESIS OF HUMAN INTERLEUKIN-2, METHOD OF THEIR CONSTRUCTION AND STRAIN OF BACTERIA ESCHERICHIA COLI RRI/pAC 262-33 AS PRODUCER OF HUMAN INTERLEUKIN-2
US5621089A (en) * 1992-05-27 1997-04-15 Novo Nordisk Biotech, Inc. Nucleic acid constructs for the production of a Bacillus alkaline protease
WO2015091967A1 (en) * 2013-12-19 2015-06-25 Basf Se Mixtures comprising a superabsorbent polymer (sap) and a biopesticide
KR20180117166A (ko) 2016-03-04 2018-10-26 다니스코 유에스 인크. 미생물에서의 단백질 생산을 위한 유전자 조작 리보솜 프로모터
KR20250054813A (ko) 2022-09-02 2025-04-23 다니스코 유에스 인크. 그람 양성 세포에서 단백질 생산을 향상시키는 신규한 프로모터 및 5'-비번역 영역 돌연변이

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US344710A (en) * 1886-06-29 Third to edward p
US4360597A (en) * 1978-06-01 1982-11-23 National Research Development Corporation Streptomyces plasmid and culture
US4273875A (en) * 1979-03-05 1981-06-16 The Upjohn Company Plasmid and process of isolating same
DE3005225A1 (de) * 1979-03-19 1980-11-20 Upjohn Co Plasmid puc3 und verfahren zu seiner isolierung
GB2048894A (en) * 1979-05-11 1980-12-17 Gist Brocades Nv Plasmid
AU545912B2 (en) * 1980-03-10 1985-08-08 Cetus Corporation Cloned heterologous jive products in bacillies
JPS56154498A (en) * 1980-04-16 1981-11-30 Upjohn Co Plasmid puc 10
DK489481A (da) * 1980-11-10 1982-05-11 Searle & Co Plasmidvektor og frmgangsmaade til fremstilling deraf
CA1170202A (en) * 1981-01-15 1984-07-03 Susan Mickel Process for cloning the gene coding for a thermostable alpha-amylase into escherichia coli and bacillus subtilis
CA1204681A (en) * 1981-04-20 1986-05-20 Cetus Corporation Method and vector organism for controlled accumulation of cloned heterologous gene products in bacillus subtilis ii
NO821391L (no) * 1981-04-29 1982-11-01 Biogen Nv Kloningsvektorer, rekombinante dna-molekyler samt bakterieverter transformert med disse
US4416994A (en) * 1981-10-19 1983-11-22 Eli Lilly And Company Plasmid pEL7 and related cloning vectors for use in streptomyces and related organisms
US4436815A (en) * 1981-11-27 1984-03-13 Eli Lilly And Company Method for stabilizing and selecting recombinant DNA containing host cells

Also Published As

Publication number Publication date
JPS59203491A (ja) 1984-11-17
US4559300A (en) 1985-12-17
EP0117041B1 (en) 1990-04-25
FI840105A7 (fi) 1984-07-19
GB2133798B (en) 1986-06-25
CA1227150A (en) 1987-09-22
AU2324084A (en) 1984-07-19
IL70661A (en) 1989-09-28
FI840105A0 (fi) 1984-01-12
GR81702B (cs) 1984-12-12
DE3482045D1 (de) 1990-05-31
GB8400829D0 (en) 1984-02-15
EP0117041A2 (en) 1984-08-29
IL70661A0 (en) 1984-04-30
FI840105L (fi) 1984-07-19
GB2133798A (en) 1984-08-01
DK11684D0 (da) 1984-01-11
EP0117041A3 (en) 1986-03-05

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