DK112391A - Fremgangsmaade og praeparat til tidlig paavisning af insulinafhaengig diabetes mellitus - Google Patents

Fremgangsmaade og praeparat til tidlig paavisning af insulinafhaengig diabetes mellitus Download PDF

Info

Publication number
DK112391A
DK112391A DK112391A DK112391A DK112391A DK 112391 A DK112391 A DK 112391A DK 112391 A DK112391 A DK 112391A DK 112391 A DK112391 A DK 112391A DK 112391 A DK112391 A DK 112391A
Authority
DK
Denmark
Prior art keywords
insulinable
procedure
preparation
diabetes mellitus
early determination
Prior art date
Application number
DK112391A
Other languages
English (en)
Other versions
DK112391D0 (da
Inventor
Mark A Atkinson
Noel K Maclaren
William Kastern
Original Assignee
Univ Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26962160&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK112391(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Univ Florida filed Critical Univ Florida
Publication of DK112391D0 publication Critical patent/DK112391D0/da
Publication of DK112391A publication Critical patent/DK112391A/da

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/573—Immunoassay; Biospecific binding assay; Materials therefor for enzymes or isoenzymes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
    • A61K47/6871—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting an enzyme
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/04—Endocrine or metabolic disorders
    • G01N2800/042—Disorders of carbohydrate metabolism, e.g. diabetes, glucose metabolism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Food Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Cell Biology (AREA)
  • General Physics & Mathematics (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK112391A 1988-12-13 1991-06-12 Fremgangsmaade og praeparat til tidlig paavisning af insulinafhaengig diabetes mellitus DK112391A (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US28363388A 1988-12-13 1988-12-13
US42705189A 1989-10-25 1989-10-25
PCT/US1989/005570 WO1990007117A1 (en) 1988-12-13 1989-12-08 Methods and compositions for the early detection and treatment of insulin dependent diabetes mellitus

Publications (2)

Publication Number Publication Date
DK112391D0 DK112391D0 (da) 1991-06-12
DK112391A true DK112391A (da) 1991-06-12

Family

ID=26962160

Family Applications (1)

Application Number Title Priority Date Filing Date
DK112391A DK112391A (da) 1988-12-13 1991-06-12 Fremgangsmaade og praeparat til tidlig paavisning af insulinafhaengig diabetes mellitus

Country Status (8)

Country Link
EP (1) EP0448635B1 (da)
KR (1) KR910700459A (da)
AU (1) AU4815890A (da)
CA (1) CA2005300C (da)
DE (1) DE68924354T2 (da)
DK (1) DK112391A (da)
ES (1) ES2077670T3 (da)
WO (1) WO1990007117A1 (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5645998A (en) 1988-12-13 1997-07-08 University Of Florida Research Foundation Methods and compositions for the early detection and treatment of insulin dependent diabetes mellitus
US6001360A (en) * 1988-12-13 1999-12-14 University Of Florida Method and compositions for early detection and treatment of insulin dependent diabetes mellitus
US5762937A (en) * 1988-12-13 1998-06-09 University Of Florida Research Foundation, Inc. Methods and compositions for the early detection and treatment of insulin dependent diabetes mellitus
US5427940A (en) * 1991-06-03 1995-06-27 Board Of Regents, The University Of Texas System Engineered cells producing insulin in response to glucose
EP0543945B1 (en) * 1990-08-17 1996-10-16 The University Of Florida Methods and compositions for early detection and treatment of insulin dependent diabetes mellitus
DK0547164T3 (da) 1990-09-07 2004-10-25 Univ California Fremgangsmåder til diagnosticering og behandling af diabetes
US5512447A (en) * 1990-09-07 1996-04-30 The Regents Of The University Of California Methods for the diagnosis and treatment of diabetes
US6682906B1 (en) * 1990-09-21 2004-01-27 The Regents Of The University Of California Cloned glutamic acid decarboxylase
US5674978A (en) * 1990-09-21 1997-10-07 The Regents Of The University Of California Peptides derived from glutamic acid decarboxylase
US5998366A (en) * 1990-09-21 1999-12-07 The Regents Of The University Of California Method for ameliorating glutamic acid decarboxylase associated autoimmune disorders
AU8864791A (en) * 1990-10-02 1992-04-28 Trigen Incorporated Antibodies and methods for diagnosis and treatment of diabetes
US5422339A (en) * 1991-03-19 1995-06-06 Joslin Diabetes Center, Inc. Peptides having insulin autoantibody but not insulin receptor binding capacity
EP0585356A1 (en) * 1991-05-15 1994-03-09 Zymogenetics, Inc. Cloning and expression of human islet glutamic acid decarboxylase autoantigen
US5407802A (en) * 1991-12-26 1995-04-18 Immulogic Pharmaceutical Corporation Method of accessing the risks of developing type I diabetes
AU3778993A (en) * 1992-02-27 1993-09-13 Board Of Trustees Of The Leland Stanford Junior University Early antigen for autoimmune diabetes
CA2118015A1 (en) * 1992-04-14 1993-10-28 Jeffrey R. Marks Method of detecting tumors containing complexes of p53 and hsp70
US5200318A (en) * 1992-05-13 1993-04-06 Miles Inc. Diagnosis of IDDM with a panel of immunoreagents
DE4237244A1 (de) * 1992-11-04 1994-05-05 Elias Entwicklungslabor Fuer I Verfahren zur Herstellung hochreiner humaner GAD-1- und GAD-2- Proteine
US5561049A (en) * 1994-09-21 1996-10-01 Behringwerke Ag Method for detecting antibodies
US6303325B1 (en) 1998-05-29 2001-10-16 Dade Behring Inc. Method for detecting analytes

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03503887A (ja) * 1988-02-03 1991-08-29 エクソウマ　コーポレーション 自己免疫疾患に対する抗ｔ細胞イムノトキシンの治療的使用

Also Published As

Publication number Publication date
DE68924354T2 (de) 1996-02-22
EP0448635B1 (en) 1995-09-20
DK112391D0 (da) 1991-06-12
ES2077670T3 (es) 1995-12-01
KR910700459A (ko) 1991-03-15
CA2005300C (en) 2000-02-15
AU4815890A (en) 1990-07-10
WO1990007117A1 (en) 1990-06-28
EP0448635A1 (en) 1991-10-02
CA2005300A1 (en) 1990-06-13
DE68924354D1 (de) 1995-10-26

Similar Documents

Publication Publication Date Title
DK112391D0 (da) Fremgangsmaade og praeparat til tidlig paavisning af insulinafhaengig diabetes mellitus
DK4191D0 (da) Polymersammensaetning og fremgangsmaade til fremstilling af denne
DK195987D0 (da) Fremgangsmaade til fremstilling af en aniosotropt ledende elastomer og anvendelse af denne
DK8787A (da) Indolderivater og fremgangsmaade til fremstilling deraf
DK620487D0 (da) Blodkarprotese og fremgangsmaade til fremstilling af denne
DK159288D0 (da) Saccharidblanding og fremgangsmaade til fremstilling deraf
DK535687A (da) Asbestfri friktionsmaterialer og fremgangsmaade til deres fremstilling
DK315484D0 (da) Farmaceutisk praeparat, specielt til behandling af diabetes og fedme
DK733788A (da) Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
DK64187A (da) Enzym-foeler og fremgangsmaade til fremstilling af en saadan
DK355387D0 (da) Overtraekspraeparat og fremgangsmaade til anvendelse deraf
DK549087D0 (da) Gangliosidbeslaegtede forbindelser og fremgangsmaade til fremstilling af samme
DK114588A (da) Sammensaetning og fremgangsmaade til immunologisk kastration og udboedning
DK448887D0 (da) Hidtil ukendt amylaseenzym og fremgangsmaade til fremstilling af samme
DK393489A (da) Benzodiazepinforbindelser og fremgangsmaade til deres fremstilling
DK362987D0 (da) Hexahydroarylquinolizin og fremgangsmaade til fremstilling deraf
DK192390D0 (da) Fremgangsmaade til fremstilling af sukkerforbindelser
DK0390762T3 (da) Hidtil ukendte bronchospasmolytiske forbindelser og fremgangsmåde til fremstilling heraf
DK221689D0 (da) Naturstensplade og fremgangsmaade til fremstilling af naturstensplade
DK106089D0 (da) Fremgangsmaade til fremstilling af alkansulfonylhalogenider og alkansulfonsyrer
DK660387A (da) Maleimidgruppeholdige formstofblandinger og fremgangsmaade til fremstilling deraf
DK436887D0 (da) Fremgangsmaade til fremstilling af triazol-tetrahydrofuran-derivater og mellemprodukter til anvendelse herved
DK129689A (da) Ifosfamid-mesna-lyofilisat og fremgangsmaade til fremstilling deraf
DK508689A (da) Organofluorider af tin og fremgangsmaade til fremstilling heraf
DK15788D0 (da) Fremgangsmaade og apparat til maaling af fuldblods koagulation

Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment