DK112381B - Process for the preparation of 16-fluoromethylene-17α-hydroxy-20-keto-steroids of the pregnane, 19-nor-pregnane or iso-pregnane series or 17α-esters thereof. - Google Patents

Process for the preparation of 16-fluoromethylene-17α-hydroxy-20-keto-steroids of the pregnane, 19-nor-pregnane or iso-pregnane series or 17α-esters thereof.

Info

Publication number
DK112381B
DK112381B DK174464A DK174464A DK112381B DK 112381 B DK112381 B DK 112381B DK 174464 A DK174464 A DK 174464A DK 174464 A DK174464 A DK 174464A DK 112381 B DK112381 B DK 112381B
Authority
DK
Denmark
Prior art keywords
pregnane
fluoromethylene
keto
steroids
iso
Prior art date
Application number
DK174464A
Other languages
Danish (da)
Inventor
E Ag Merck
Original Assignee
E Ag Merck
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by E Ag Merck filed Critical E Ag Merck
Publication of DK112381B publication Critical patent/DK112381B/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J5/00Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J7/00Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J75/00Processes for the preparation of steroids in general

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
DK174464A 1963-04-13 1964-04-08 Process for the preparation of 16-fluoromethylene-17α-hydroxy-20-keto-steroids of the pregnane, 19-nor-pregnane or iso-pregnane series or 17α-esters thereof. DK112381B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DEM56495A DE1296631B (en) 1963-04-13 1963-04-13 Process for the preparation of 16-fluoromethylene steroids

Publications (1)

Publication Number Publication Date
DK112381B true DK112381B (en) 1968-12-09

Family

ID=7308637

Family Applications (1)

Application Number Title Priority Date Filing Date
DK174464A DK112381B (en) 1963-04-13 1964-04-08 Process for the preparation of 16-fluoromethylene-17α-hydroxy-20-keto-steroids of the pregnane, 19-nor-pregnane or iso-pregnane series or 17α-esters thereof.

Country Status (4)

Country Link
BR (1) BR6457941D0 (en)
DE (1) DE1296631B (en)
DK (1) DK112381B (en)
NL (1) NL6401411A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2104970B1 (en) * 1970-09-11 1973-11-30 Ciba Geigy Ag

Also Published As

Publication number Publication date
BR6457941D0 (en) 1973-07-17
NL6401411A (en) 1964-11-25
DE1296631B (en) 1969-06-04

Similar Documents

Publication Publication Date Title
DK112949B (en) Process for the preparation of O-mycaminosyl tylonolide or dihydro-O-mycaminosyl tylonolide.
DK108500C (en) Process for the preparation of 1-glycosyl-5-azacytosines.
DK111889B (en) Process for the preparation of 3-N-substituted tricycloundecanes.
DK106185C (en) Process for the preparation of 17α-acyloxy-4,6-pregnadien-20-ones.
DK120596B (en) Process for the preparation of acetoxymethylbenzylpenicillinate.
DK104461C (en) Process for the preparation of 3-amino-isoxazoles.
DK121120B (en) Process for the preparation of 3-hydroxy-Δ <1.5> -androstadienes or 3-esters or 3-ethers thereof.
DK116056B (en) Process for the preparation of 13-alkyl-gona-4,9-dien-3-ones or their D-homo-analogues.
DK106328C (en) Process for the preparation of 17α-alkoxy-16-methylene-3,20-diketopregnane derivatives.
DK107031C (en) Process for the preparation of 2-halomethyl-quinazoline-3-oxides.
DK104571C (en) Process for the preparation of trans-2-phenyl-3-methylmorpholine.
DK115327B (en) Process for the preparation of hydroxyphenylalkylphosphonates.
DK112381B (en) Process for the preparation of 16-fluoromethylene-17α-hydroxy-20-keto-steroids of the pregnane, 19-nor-pregnane or iso-pregnane series or 17α-esters thereof.
DK111141B (en) Process for the preparation of 2'-acetamido-2'-deoxyglucosides or galactosides of 17α, 21-dihydroxy-11-oxygenated -3,20-diketo-steroids of the pregnane series.
DK113991B (en) Process for the preparation of 2-chloro-3-oxo-butanamides.
DK122883B (en) Process for the preparation of ω-lactams.
DK106494C (en) Process for the preparation of 11β-hydroxy-17α-ethinyl estradiol or its 3-esters or 3-ethers.
DK108499C (en) Process for the preparation of 1-alkyl- or 1-hydroxyalkyl-5-nitro-imidazole-2-carboxamides.
DK118818B (en) Process for the preparation of 3-keto-4,6-bisdehydro-9β, 10α-steroids.
DK121297B (en) Process for the preparation of 19-hydroxyandrost-4-ene-3,17-dione.
DK105983C (en) Process for the preparation of 2-alkoxy-5-aryl-3H-1,4-benzodiazepine-4-oxides.
DK101415C (en) Process for the preparation of 16-halomethylene-17α-hydroxy-20-keto-steroids of the pregnane, 19-norpregnan or iso-pregnane series or 17α-esters thereof.
DK106142C (en) Process for the preparation of 11α17α21-trihydroxy-9β, 10α-4-pregnene-3,20-dione.
DK129243B (en) Process for the preparation of 6-demethyltetracyclines.
DK120764B (en) Process for the preparation of 2-amino-5-nitro-benzophenones.