DK1123089T3 - Chewable tablet with masked taste and immediate release of the active substance and process for its preparation - Google Patents

Chewable tablet with masked taste and immediate release of the active substance and process for its preparation

Info

Publication number
DK1123089T3
DK1123089T3 DK99950805T DK99950805T DK1123089T3 DK 1123089 T3 DK1123089 T3 DK 1123089T3 DK 99950805 T DK99950805 T DK 99950805T DK 99950805 T DK99950805 T DK 99950805T DK 1123089 T3 DK1123089 T3 DK 1123089T3
Authority
DK
Denmark
Prior art keywords
preparation
active substance
immediate release
chewable tablet
masked taste
Prior art date
Application number
DK99950805T
Other languages
Danish (da)
Inventor
Philippe Barthelemy
Hassan Benameur
Geraldine Cruminian
Original Assignee
Gattefosse Ets Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gattefosse Ets Sa filed Critical Gattefosse Ets Sa
Application granted granted Critical
Publication of DK1123089T3 publication Critical patent/DK1123089T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1617—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5015—Organic compounds, e.g. fats, sugars

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention concerns a tablet for crunching with masked taste and instant release of the active principle characterised in that it consists of a mixture comprising: individualised particles of active principle coated with a lipid agent resulting from a reaction between at least a polyhydroxyalcohol and at least a saturated fatty acid, said fatty acid comprising 8 to 22 carbon atoms; and at least a binding-disintegrating agent. The invention also concerns the method for making said tablet.
DK99950805T 1998-10-23 1999-10-21 Chewable tablet with masked taste and immediate release of the active substance and process for its preparation DK1123089T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9813466A FR2784895B1 (en) 1998-10-23 1998-10-23 MASK TASTE CHEWABLE TABLET AND IMMEDIATE RELEASE OF THE ACTIVE INGREDIENT AND MANUFACTURING METHOD
PCT/FR1999/002563 WO2000024385A1 (en) 1998-10-23 1999-10-21 Tablet for crunching with masked taste and instant release of active principle and method for making same

Publications (1)

Publication Number Publication Date
DK1123089T3 true DK1123089T3 (en) 2003-10-13

Family

ID=9532051

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99950805T DK1123089T3 (en) 1998-10-23 1999-10-21 Chewable tablet with masked taste and immediate release of the active substance and process for its preparation

Country Status (10)

Country Link
EP (1) EP1123089B1 (en)
JP (1) JP2002528409A (en)
KR (1) KR20010080239A (en)
AT (1) ATE249208T1 (en)
AU (1) AU6344899A (en)
DE (1) DE69911224T2 (en)
DK (1) DK1123089T3 (en)
ES (1) ES2205887T3 (en)
FR (1) FR2784895B1 (en)
WO (1) WO2000024385A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1313589B1 (en) * 1999-08-03 2002-09-09 Formenti Farmaceutici Spa PARACETAMOL CONTROLLED RELEASE COMPOSITIONS.
JP2002138034A (en) * 2000-10-27 2002-05-14 Kyoto Pharmaceutical Industries Ltd Bitter taste masked chewable tablet and preparation method of the same
CA2452330C (en) 2001-07-06 2011-03-22 Lifecycle Pharma A/S Controlled agglomeration
FR2831820B1 (en) * 2001-11-05 2004-08-20 Ethypharm Sa ORODISPERSIBLE TABLET HAVING HIGH HOMOGENEITY AND PREPARATION METHOD THEREOF
AU2005280679A1 (en) * 2004-09-02 2006-03-09 Quest International Services B.V. Heat stable flavouring compositions
JP4565219B2 (en) * 2008-12-26 2010-10-20 アサヒビール株式会社 Polyphenol-containing granule or polyphenol-containing chewable tablet and method for producing the same
WO2013143688A1 (en) 2012-03-26 2013-10-03 Glatt Ag Taste-masked ibuprofen granules
FR3027802B1 (en) 2014-10-31 2018-03-02 Ethypharm DOUBLE MASKING TASTE ACTIVE PRINCIPLE GRANULES, PROCESS FOR THEIR PREPARATION AND ORODISPERSIBLE TABLETS CONTAINING SAME

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8730011D0 (en) * 1987-12-23 1988-02-03 Smithkline Dauelsberg Pharmaceutical compositions
CA2019324C (en) * 1989-07-10 1996-08-20 Robert L. Jerzewski Fosinopril tablet formulations
GB9224855D0 (en) * 1992-11-27 1993-01-13 Smithkline Beecham Plc Pharmaceutical compositions
JPH0971523A (en) * 1995-09-07 1997-03-18 Riyuukakusan:Kk Tablet quickly disintegrating in oral cavity
FR2753904B1 (en) * 1996-10-01 1998-10-30 Gattefosse Ets Sa PHARMACEUTICAL COMPOSITION WITH MODIFIED RELEASE OF ACTIVE SUBSTANCE, INCLUDING A MATRIX, AND MANUFACTURING PROCESS
EP0839526A3 (en) * 1996-10-31 1999-01-07 Takeda Chemical Industries, Ltd. Solid pharmaceutical preparation with fast buccal disintegration or dissolution
US5891476A (en) * 1997-12-22 1999-04-06 Reo; Joe P. Tastemasked pharmaceutical system

Also Published As

Publication number Publication date
EP1123089A1 (en) 2001-08-16
KR20010080239A (en) 2001-08-22
AU6344899A (en) 2000-05-15
DE69911224T2 (en) 2004-07-15
FR2784895A1 (en) 2000-04-28
DE69911224D1 (en) 2003-10-16
ATE249208T1 (en) 2003-09-15
FR2784895B1 (en) 2004-12-17
JP2002528409A (en) 2002-09-03
ES2205887T3 (en) 2004-05-01
WO2000024385A1 (en) 2000-05-04
EP1123089B1 (en) 2003-09-10

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