DK109779C - Fremgangsmåde til fremstilling af 3-aminopyrazinamidoguanidinforbindelser eller syreadditionssalte heraf. - Google Patents
Fremgangsmåde til fremstilling af 3-aminopyrazinamidoguanidinforbindelser eller syreadditionssalte heraf.Info
- Publication number
- DK109779C DK109779C DK476964AA DK476964A DK109779C DK 109779 C DK109779 C DK 109779C DK 476964A A DK476964A A DK 476964AA DK 476964 A DK476964 A DK 476964A DK 109779 C DK109779 C DK 109779C
- Authority
- DK
- Denmark
- Prior art keywords
- aminopyrazinamidoguanidine
- compounds
- preparation
- acid addition
- addition salts
- Prior art date
Links
- KBFYRIILGLOEQS-UHFFFAOYSA-N 3-amino-N-(diaminomethylideneamino)pyrazine-2-carboxamide Chemical class NC=1C(=NC=CN1)C(=O)NNC(=N)N KBFYRIILGLOEQS-UHFFFAOYSA-N 0.000 title 1
- 239000002253 acid Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D241/00—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
- C07D241/02—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
- C07D241/10—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
- C07D241/14—Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D241/24—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D241/26—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with nitrogen atoms directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US23421362A | 1962-10-30 | 1962-10-30 | |
| US311291A US3300494A (en) | 1962-10-30 | 1963-09-27 | Pyrazinamidoguanidine products |
| US356041A US3325494A (en) | 1962-10-30 | 1964-03-31 | Process for preparing pyrazinamidoguanidines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK109779C true DK109779C (da) | 1968-07-01 |
Family
ID=27398533
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK476964AA DK109779C (da) | 1962-10-30 | 1963-10-30 | Fremgangsmåde til fremstilling af 3-aminopyrazinamidoguanidinforbindelser eller syreadditionssalte heraf. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US3325494A (de) |
| BE (1) | BE653480A (de) |
| CH (1) | CH503747A (de) |
| DE (1) | DE1470076A1 (de) |
| DK (1) | DK109779C (de) |
| FR (1) | FR95002E (de) |
| GB (1) | GB1083997A (de) |
| NL (1) | NL6409715A (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3527759A (en) * | 1967-09-29 | 1970-09-08 | Merck & Co Inc | Process for the preparation of pyrazinamidoguanidines |
| US6858615B2 (en) | 2002-02-19 | 2005-02-22 | Parion Sciences, Inc. | Phenyl guanidine sodium channel blockers |
| US6903105B2 (en) | 2003-02-19 | 2005-06-07 | Parion Sciences, Inc. | Sodium channel blockers |
| US20050090505A1 (en) * | 2003-08-18 | 2005-04-28 | Johnson Michael R. | Methods of reducing risk of infection from pathogens |
| US7745442B2 (en) * | 2003-08-20 | 2010-06-29 | Parion Sciences, Inc. | Methods of reducing risk of infection from pathogens |
| AR086745A1 (es) | 2011-06-27 | 2014-01-22 | Parion Sciences Inc | 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida |
| US9593084B2 (en) | 2012-12-17 | 2017-03-14 | Parion Sciences, Inc. | Chloro-pyrazine carboxamide derivatives with epithelial sodium channel blocking activity |
| WO2014099673A1 (en) | 2012-12-17 | 2014-06-26 | Parion Sciences, Inc. | 3,5-diamino-6-chloro-n-(n-(4-phenylbutyl)carbamimidoyl) pyrazine-2- carboxamide compounds |
| US9102633B2 (en) | 2013-12-13 | 2015-08-11 | Parion Sciences, Inc. | Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2959616A (en) * | 1955-09-28 | 1960-11-08 | Ici Ltd | Guanidines |
-
1963
- 1963-10-30 DK DK476964AA patent/DK109779C/da active
-
1964
- 1964-03-31 US US356041A patent/US3325494A/en not_active Expired - Lifetime
- 1964-07-08 DE DE19641470076 patent/DE1470076A1/de active Pending
- 1964-08-10 FR FR984737A patent/FR95002E/fr not_active Expired
- 1964-08-21 NL NL6409715A patent/NL6409715A/xx unknown
- 1964-09-23 BE BE653480D patent/BE653480A/xx unknown
- 1964-10-06 GB GB40721/64A patent/GB1083997A/en not_active Expired
-
1965
- 1965-01-27 CH CH113165A patent/CH503747A/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FR95002E (fr) | 1970-03-27 |
| DE1470076A1 (de) | 1969-02-20 |
| US3325494A (en) | 1967-06-13 |
| BE653480A (de) | 1965-03-23 |
| CH503747A (de) | 1971-02-28 |
| NL6409715A (de) | 1965-10-01 |
| GB1083997A (en) | 1967-09-20 |
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