DK105020C - Fremgangsmåde til fremstilling af 21-dihydrogenphosphater af 16α,17α-acetaler eller -ketaler af 6-halogen-4-pregnen-16α,17α,21-triol-3,20-dioner eller alkalimetalsalte heraf. - Google Patents

Fremgangsmåde til fremstilling af 21-dihydrogenphosphater af 16α,17α-acetaler eller -ketaler af 6-halogen-4-pregnen-16α,17α,21-triol-3,20-dioner eller alkalimetalsalte heraf.

Info

Publication number
DK105020C
DK105020C DK36262AA DK36262A DK105020C DK 105020 C DK105020 C DK 105020C DK 36262A A DK36262A A DK 36262AA DK 36262 A DK36262 A DK 36262A DK 105020 C DK105020 C DK 105020C
Authority
DK
Denmark
Prior art keywords
pregnene
diones
ketals
acetals
triol
Prior art date
Application number
DK36262AA
Other languages
English (en)
Original Assignee
Olin Mathieson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Olin Mathieson filed Critical Olin Mathieson
Application granted granted Critical
Publication of DK105020C publication Critical patent/DK105020C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK36262AA 1961-01-26 1962-01-25 Fremgangsmåde til fremstilling af 21-dihydrogenphosphater af 16α,17α-acetaler eller -ketaler af 6-halogen-4-pregnen-16α,17α,21-triol-3,20-dioner eller alkalimetalsalte heraf. DK105020C (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US85002A US3053834A (en) 1961-01-26 1961-01-26 21-phosphates of steroid acetals and ketals

Publications (1)

Publication Number Publication Date
DK105020C true DK105020C (da) 1966-08-08

Family

ID=22188584

Family Applications (1)

Application Number Title Priority Date Filing Date
DK36262AA DK105020C (da) 1961-01-26 1962-01-25 Fremgangsmåde til fremstilling af 21-dihydrogenphosphater af 16α,17α-acetaler eller -ketaler af 6-halogen-4-pregnen-16α,17α,21-triol-3,20-dioner eller alkalimetalsalte heraf.

Country Status (7)

Country Link
US (1) US3053834A (da)
BE (1) BE613053A (da)
BR (1) BR6235732D0 (da)
CH (1) CH401958A (da)
DK (1) DK105020C (da)
FR (1) FR2159M (da)
GB (1) GB990081A (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3138528A (en) * 1962-05-01 1964-06-23 Olin Mathieson Stable, aqueous solutions of 21-phosphate esters of 21-hydroxy steroids
US3966778A (en) * 1965-05-08 1976-06-29 Takeda Chemical Industries, Ltd. Production of 21-phosphate corticords having unprotected hydroxyl radicals at least at the 17α- and 21-position
GB1281689A (en) * 1968-10-14 1972-07-12 Glaxo Lab Ltd Steroid 21-phosphates
DE3440794A1 (de) * 1984-11-08 1986-05-15 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von corticosteroid-21-phosphorsaeuren und deren salzen und die corticosteroid-21-phosphorsaeuretriester
US4910192A (en) * 1987-12-04 1990-03-20 Sri International Topically active steroidal anti-inflammatory agents
CA2669355C (en) * 2006-11-06 2012-10-30 Jina Pharmaceuticals, Inc. Guggulphospholipid methods and compositions
WO2012158977A2 (en) 2011-05-18 2012-11-22 Vishay-Siliconix Semiconductor device

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2183589A (en) * 1939-12-19 Derivatives of compounds of the
US2779775A (en) * 1954-09-30 1957-01-29 Merck & Co Inc Phosphate derivatives of 9alpha-fluorosteroids
US2932657A (en) * 1957-07-30 1960-04-12 Merck & Co Inc Purification of steroid phosphate esters
US2990401A (en) * 1958-06-18 1961-06-27 American Cyanamid Co 11-substituted 16alpha, 17alpha-substituted methylenedioxy steroids
US2966486A (en) * 1959-03-20 1960-12-27 American Cyanamid Co 16alpha, 17alpha-substituted methylene dioxy ethers of steroids of the pregnane series and method of preparing the same

Also Published As

Publication number Publication date
BR6235732D0 (pt) 1973-05-24
BE613053A (fr) 1962-07-14
US3053834A (en) 1962-09-11
GB990081A (en) 1965-04-22
CH401958A (fr) 1965-11-15
FR2159M (fr) 1963-11-25

Similar Documents

Publication Publication Date Title
DK117563B (da) Analogifremgangsmåde til fremstilling af 17α,21-(1'-alkyl-1'-alkoxy-methylendioxy)-11β-hydroxy-9-α-halogen-16β-methyl-1,4-pregnadien-3,20-dioner.
DK124079B (da) Fremgangsmåde til fremstilling a 3-oxo-Δ<4,6>-9β, 10α-steroider af androstanrækken eller pregnanrækken.
DK105020C (da) Fremgangsmåde til fremstilling af 21-dihydrogenphosphater af 16α,17α-acetaler eller -ketaler af 6-halogen-4-pregnen-16α,17α,21-triol-3,20-dioner eller alkalimetalsalte heraf.
DK130991B (da) Fremgangsmåde til fremstilling af 16beta-metyl-9alfa-fluor-11beta-17alfa,21-trihydroxy-1,4-pregnadien-3,20-dion eller dets 21-acylater.
DK108281C (da) Fremgangsmåde til fremstilling af 17α,21-dihydroxy-steroider eller 21-estere deraf.
DK105065C (da) Fremgangsmåde til fremstilling af 16α,17α-acetaler eller -ketaler af 3-oxo-16α,17α-dihydroxy-19-nor-4-pregnener eller 3-oxo-16α,17α-dihydroxy-19-nor-5(10)-pregnener.
DK108860C (da) Fremgangsmåde til fremstilling af 11-oxygenerede 6α-fluor-9α-halogen-16β-methyl-1,4-pregnadien-17α,21-diol-3,20-dioner eller 21-estere deraf.
DK118556B (da) Analogifremgangsmåde til fremstilling af 16α-methyl-9α-chlor-Δ<1,4>-pregnadien-11β,21-diol-3,20-dioner eller 21-estere deraf.
DK98178C (da) Fremgangsmåde til fremstilling af 9α-fluor-16-methylen-1,4-pregnadien-11β,17α,21-triol-3,20-dion eller 21-estere deraf.
DK106608C (da) Fremgangsmåde til fremstilling af 16α-chlormethyl-Δ<1,4>-pregnadien- 11β,21-diol-3,20-dion eller 21-estere deraf.
DK105019C (da) Fremgangsmåde til fremstilling af 6α-chlor- eller 6α-brom-9α-flour-16α-methyl-Δ<1,4>-pregnadien-17α,21-diol-3,20-dioner eller estere heraf.
DK97940C (da) Fremgangsmåde til fremstilling af 16-halogenmethylen-1,4-pregnadienforbindelser eller 21-estere deraf.
DK95172C (da) Fremgangsmåde til fremstilling af 2-alkyl-11β,17α,21-trihydroxy-4-pregnen-3,20-dioner eller 21-estere heraf.
DK113146B (da) Fremgangsmåde til fremstilling af terapeutisk virksomme 6-halogen-1α,2α-methylen-16α-methyl-&Delta<4,6>-pregnadien-17α-ol-3,20-dioner eller deres 17-estere.
DK100367C (da) Fremgangsmåde til fremstilling af 16-amino-4-pregnen-17α-ol-3,20-dioner eller salte deraf.
DK114620B (da) Fremgangsmåde til fremstilling af 6-chlor-16α-methyl-Δ<4,6>-pregnadien-17α-ol-3,20-dion eller dens 17-estere.
DK128606B (da) Fremgangsmåde til fremstilling af 16β-metylprednison eller 21-acetatet deraf.
DK105403C (da) Fremgangsmåde til fremstilling af 1'-substituerede 17α,21-(1'-alkoxy)-methylendioxysteroider.
DK111615B (da) Fremgangsmåde til fremstilling af 6α,9α-difluor-16α-metyl-Δ<1,4>-pregnadien-11β,21-diol-3,20-dion eller estere deraf.
DK98495C (da) Fremgangsmåde til fremstilling af 16α,17α-acetaler eller -ketaler af 6-halogen-4-pregnen-16α,17α-diol-3,20-dion.
DK130646B (da) Analogifremgangsmåde til fremstilling af 17- og/eller 21-alkanoyloxy-11beta-klor-16beta-metylpregna-1,4-dien-3,20-dioner.
DK89681C (da) Fremgangsmåde til fremstilling af 16α,21-dialkanoyloxy-17α-hydroxy-9β,11β-oxido-1,4-pregnadien-3,20-dioner.
DK129452B (da) Analogifremgangsmåde til fremstilling af 9α-fluor-11β,21-dihydroxy-pregna-1,4-dien-3,20-dion-[17α,16α-d]-oxazolidiner eller oxazolidinooxaziner.
DK94617C (da) Fremgangsmåde til fremstilling af 21-dicarboxylsyremonoestere af 16α,17α-acetal- eller -ketalderivater af 16α,17α,21-trihydroxypregnanforbindelser eller vandopløselige salte deraf.
DK121369B (da) Fremgangsmåde til fremstilling af 3-oxo-Δ<4>-steroider, 3-oxo-Δ<5(10)>-steroider eller enolethere deraf.