DK0929294T3 - Process for the preparation of low-dose free-flowing and / or directly compressible powder systems - Google Patents

Process for the preparation of low-dose free-flowing and / or directly compressible powder systems

Info

Publication number
DK0929294T3
DK0929294T3 DK97921603T DK97921603T DK0929294T3 DK 0929294 T3 DK0929294 T3 DK 0929294T3 DK 97921603 T DK97921603 T DK 97921603T DK 97921603 T DK97921603 T DK 97921603T DK 0929294 T3 DK0929294 T3 DK 0929294T3
Authority
DK
Denmark
Prior art keywords
flowing
preparation
low
directly compressible
powder systems
Prior art date
Application number
DK97921603T
Other languages
Danish (da)
Inventor
Felix Specht
Original Assignee
Felix Specht
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Felix Specht filed Critical Felix Specht
Application granted granted Critical
Publication of DK0929294T3 publication Critical patent/DK0929294T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Noodles (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A process for producing small doses of fluid and/or directly compressible powder systems is characterised in that at least one active substance in a solution or dispersion is sprayed on the powder system.
DK97921603T 1996-04-04 1997-04-04 Process for the preparation of low-dose free-flowing and / or directly compressible powder systems DK0929294T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19613545 1996-04-04
PCT/DE1997/000691 WO1997037638A2 (en) 1996-04-04 1997-04-04 Process for producing small doses of fluid and/or directly compressible powder systems

Publications (1)

Publication Number Publication Date
DK0929294T3 true DK0929294T3 (en) 2003-09-29

Family

ID=7790499

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97921603T DK0929294T3 (en) 1996-04-04 1997-04-04 Process for the preparation of low-dose free-flowing and / or directly compressible powder systems

Country Status (7)

Country Link
EP (1) EP0929294B1 (en)
AT (1) ATE243500T1 (en)
DE (2) DE59710349D1 (en)
DK (1) DK0929294T3 (en)
ES (1) ES2201298T3 (en)
PT (1) PT929294E (en)
WO (1) WO1997037638A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1312110B1 (en) 1999-05-18 2002-04-04 Istituto Biochimico Pavese Pha NATURAL ANTIBIOTIC-POLYESACCHARIDIC POLYMER ADDUCTS
EE05442B1 (en) 2000-02-29 2011-08-15 Bristol-Myers Squibb Company A low dose entecavir pharmaceutical composition for the treatment of hepatitis B virus infection and a method for its preparation
US20070202179A1 (en) * 2004-04-09 2007-08-30 FAULKNER Patrick Low Dose Pharmaceutical Products
EP2453878A1 (en) * 2009-07-16 2012-05-23 Avantor Performance Materials, Inc. Material and process for incorporation of low dosage active pharmaceutical ingredients and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3836618A (en) * 1971-12-23 1974-09-17 American Home Prod Process for the uniform distribution of a drug on a granulated base
US5026560A (en) * 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
CA1338596C (en) * 1988-09-27 1996-09-17 Hiroyoshi Koyama Granules having core and their production
GB9114374D0 (en) * 1991-07-03 1991-08-21 Smithkline Beecham Plc Novel process
JP3349535B2 (en) * 1993-01-12 2002-11-25 フロイント産業株式会社 Method for producing spherical granules

Also Published As

Publication number Publication date
DE19714024A1 (en) 1997-11-20
DE59710349D1 (en) 2003-07-31
ES2201298T3 (en) 2004-03-16
WO1997037638A2 (en) 1997-10-16
WO1997037638A3 (en) 1997-12-04
PT929294E (en) 2003-11-28
EP0929294A2 (en) 1999-07-21
ATE243500T1 (en) 2003-07-15
EP0929294B1 (en) 2003-06-25

Similar Documents

Publication Publication Date Title
NZ236002A (en) Transdermal delivery system for 2-amino-6-n-propylamino-4,5,6,7-tetrahydrobenzothiazole
EP0189861A3 (en) Percutaneous absorption accelerator for ionic water-soluble medicine
NO922584D0 (en) PROCEDURE FOR SYNCHRONIZING SYSTEMS FOR SEISMIC INVESTIGATIONS, AND APPLICATIONS OF THE PROCEDURE
NO874873L (en) DEVICE FOR AUTO-ADMINISTRATION OF PHYSIOLOGICALLY ACTIVE SUBSTANCES, WITHOUT OVERDOSAGE PREVENTION.
SE9801287D0 (en) Incorporation of active substances into carrier matrixes
NO911260D0 (en) DELIVERY SYSTEM FOR ARMASTIC AND SWEATING AGENTS, AND PROCEDURE FOR THE PREPARATION OF SUCH A SYSTEM.
ES2143500T3 (en) METHOD AND APPARATUS FOR COMMUNICATING SIGNALS.
BR9707336A (en) Continuous dosing of an active agent using an implantable system
DK470082A (en) TETRAHYDROPHTHALIMIDES, METHOD OF PREPARING IT AND USING ITS ACTIVE INGREDIENT IN HERBICIDES
TR28155A (en) Active substance delivery system.
AU5174193A (en) Process and device for producing liquid, dispersed systems
DE3261497D1 (en) Substituted n-(4-indolyl-piperidino-alkyl) benzimidazolones, processes for their preparation and their use as pharmaceutical preparations
AU2636992A (en) Device for the pulsating delivery of an irrigation liquid, and irrigation systems which incorporate the device
NO963588L (en) Granulated product or tablet containing an effervescent system and an active pharmaceutical substance, and a process for the preparation thereof
DK0929294T3 (en) Process for the preparation of low-dose free-flowing and / or directly compressible powder systems
FR2796840B1 (en) LOW-DOSE TABLETS AND METHOD OF PREPARATION
JPS5299207A (en) Remedy for cattle diarrhea
NO903347L (en) 14,17ALFA ETHANO AND ETHANOESTRATRIANS, PROCEDURE FOR THE PREPARATION OF THESE COMPOUNDS, AS WELL AS THE USE OF THEM FOR THE PREPARATION OF PHARMACEUTICALS.
EP0261524A3 (en) Medicinal preparations
DK0691885T3 (en) Method for Encapsulating Substances in Biocapsules
NO306993B1 (en) Piperidinylmethyloxyzolidin-2-one derivatives, pharmaceutical preparations containing such, and use of the compounds in the manufacture of medicinal products
EP0583606A3 (en) New hydrazono-5-beta-androstane derivatives active on the cardiovascular system, processes for their preparation and pharmaceutical compositions containing same.
AU7817891A (en) Pharmaceuaticals with delayed release of active agent
FR2703926B1 (en) Stable micro-emulsion providing a dry contact spray, preparation process and implementation device.
EP0482213A4 (en) Antineoplastic agent