DK0921807T3 - Hydrogen-containing drug - Google Patents

Hydrogen-containing drug

Info

Publication number
DK0921807T3
DK0921807T3 DK97944778T DK97944778T DK0921807T3 DK 0921807 T3 DK0921807 T3 DK 0921807T3 DK 97944778 T DK97944778 T DK 97944778T DK 97944778 T DK97944778 T DK 97944778T DK 0921807 T3 DK0921807 T3 DK 0921807T3
Authority
DK
Denmark
Prior art keywords
hydrogenous
gas mixtures
hydrogen
gas
inflammatory processes
Prior art date
Application number
DK97944778T
Other languages
Danish (da)
Inventor
Christian Krebs
Bonn Rolf Van
Peter Germann
Manfred Eschwey
Original Assignee
Messer Griesheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19634530A external-priority patent/DE19634530A1/en
Priority claimed from DE1997134279 external-priority patent/DE19734279A1/en
Application filed by Messer Griesheim Gmbh filed Critical Messer Griesheim Gmbh
Application granted granted Critical
Publication of DK0921807T3 publication Critical patent/DK0921807T3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention concerns hydrogenous gas mixtures which are suitable for preparing medicaments for treating inflammatory processes in humans and mammals, in particular for treating inflammatory processes in the lungs. Deuterium-containing gas mixtures are used for treating cancer. In addition to hydrogen, the hydrogenous gas mixtures can contain a pharmacologically active gas, such as nitric oxide, carbon monoxide, nitrous oxide, acetylene or ethylene. The hydrogenous medicament is used as an inhalant gas in the form of suppositories, ointments, solutions, dispersions, emulsions, microdroplets, microbubbles, liposomes, microparticles, aerosols, foams, particulate agents, pills, pastilles, capsules, microcapsules, chewing-gum, in carriers or as part of a plaster.
DK97944778T 1996-08-27 1997-08-22 Hydrogen-containing drug DK0921807T3 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19634530A DE19634530A1 (en) 1996-08-27 1996-08-27 Alteration of formation rate or half-life of reactive molecular species
DE1997134279 DE19734279A1 (en) 1997-08-07 1997-08-07 Pharmaceutical compositions containing hydrogen gas
PCT/EP1997/004567 WO1998008523A1 (en) 1996-08-27 1997-08-22 Hydrogenous medicament

Publications (1)

Publication Number Publication Date
DK0921807T3 true DK0921807T3 (en) 2004-03-15

Family

ID=26028775

Family Applications (1)

Application Number Title Priority Date Filing Date
DK97944778T DK0921807T3 (en) 1996-08-27 1997-08-22 Hydrogen-containing drug

Country Status (11)

Country Link
EP (1) EP0921807B1 (en)
JP (1) JP2000517311A (en)
CN (1) CN1191836C (en)
AT (1) ATE253372T1 (en)
DE (1) DE59710969D1 (en)
DK (1) DK0921807T3 (en)
ES (1) ES2210585T3 (en)
HK (1) HK1021885A1 (en)
HR (1) HRP970465A2 (en)
PT (1) PT921807E (en)
WO (1) WO1998008523A1 (en)

Families Citing this family (52)

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US8128963B2 (en) 1996-09-27 2012-03-06 The Trustees Of Columbia University In The City Of New York Methods for treating ischemic disorders using carbon monoxide
DE19833014A1 (en) * 1998-07-23 2000-01-27 Messer Griesheim Gmbh Injectable anesthetic comprising noble gas(es) in gaseous form, also showing analgesic, sedative, antiinflammatory and muscle relaxant actions
US7678390B2 (en) * 1999-04-01 2010-03-16 Yale University Carbon monoxide as a biomarker and therapeutic agent
FR2812197B1 (en) * 2000-07-27 2003-01-03 Air Liquide Sante Int USE OF CO IN THE TREATMENT OF INFLAMMATION OF THE UPPER AIRWAYS OR BRONCHIA
SI1404811T1 (en) 2001-06-21 2009-04-30 Beth Israel Hospital Carbon monoxide improves outcomes in tissue and organ transplants and suppresses apoptosis
JP2005525848A (en) 2002-02-13 2005-09-02 ベス イスラエル ディコネス メディカル センター Treatment method of vascular disease
WO2003088923A2 (en) 2002-04-15 2003-10-30 University Of Pittsburgh Of The Commonwealth System Of Higher Education Methods of treating ileus
CA2482260A1 (en) 2002-04-15 2003-10-30 Beth Israel Deaconess Medical Center Inc. Use of heme oxygenase-1 and products of heme degradation
WO2003088981A1 (en) 2002-04-15 2003-10-30 University Of Pittsburgh Of The Commonwealth System Of Higher Education Methods of treating necrotizing enterocolitis
WO2004039735A1 (en) * 2002-04-26 2004-05-13 Miz Co., Ltd. Method of inhibiting oxidation, water capable of inhibiting oxidation and use thereof
CA2484770A1 (en) * 2002-05-09 2003-11-20 Yale University Carbon monoxide as a biomarker and therapeutic agent
UA83465C2 (en) 2002-05-17 2008-07-25 Йельский Университет Method of treating hepatitis with carbon monoxide
WO2006064539A1 (en) * 2004-12-13 2006-06-22 Wataru Murota Reducing physiological saline solutions and process for the production thereof
US20090035383A1 (en) 2005-08-19 2009-02-05 Shigeo Ohta Scavenger of in vivo harmful reactive oxygen species and/or free radicals
EP2057990A4 (en) 2006-08-31 2010-08-04 Ohta Shigeo Lipid metabolism improving agent containing hydrogen molecule
DE102008054205A1 (en) * 2008-10-31 2010-05-06 Bayer Schering Pharma Aktiengesellschaft Use of helium-oxygen gas mixtures for the treatment of pulmonary arterial hypertension
EP2474327A1 (en) 2011-01-07 2012-07-11 RWTH Aachen Microdosing of ultrasound contrast agents
CA2830298C (en) 2011-03-17 2016-08-16 Transdermal Biotechnology, Inc. Topical nitric oxide systems comprising lecithin and methods of use thereof
EP2545908A1 (en) 2011-07-11 2013-01-16 RWTH Aachen Medium for microbubbles or microparticles and preparation thereof
CN103565822B (en) * 2012-08-05 2015-03-25 熊江 Application of hydrogen saturated physiological saline in preparing medicines for preventing and treating abdominal aortic aneurysm
US8871260B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Methods and compositions for muscular and neuromuscular diseases
US8871256B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Methods and systems for treatment of inflammatory diseases with nitric oxide
US8871262B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Compositions and methods for treatment of osteoporosis and other indications
US8871258B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Treatment and prevention of learning and memory disorders
US8871255B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Treatment of skin and soft tissue infection with nitric oxide
US8871259B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Techniques and systems for treatment of neuropathic pain and other indications
US8871257B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Prevention and treatment of cardiovascular diseases using systems and methods for transdermal nitric oxide delivery
US8871254B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Systems and methods for treatment of acne vulgaris and other conditions with a topical nitric oxide delivery system
US8871261B2 (en) 2012-09-19 2014-10-28 Transdermal Biotechnology, Inc. Cancer treatments and compositions for use thereof
CN103099780B (en) * 2012-12-11 2015-11-25 中国科学院深圳先进技术研究院 Prepare the method for hydrogen microvesicle aqueous solution, its product and application
WO2014140197A1 (en) 2013-03-15 2014-09-18 Westfaelische Wilhelms-Universitaet Muenster Detection of acute renal allograft rejection
EP3064211B1 (en) 2013-10-31 2020-04-01 Hirota, Masanori Sperm-motility enhancer
CN103690481B (en) * 2013-12-23 2016-09-07 中国人民解放军第二军医大学 Methane injection application in preparation treatment ischemical reperfusion injury medicine
TWI590837B (en) * 2014-03-25 2017-07-11 林信湧 Inhalation-type pharmaceutical composition for heart disease and preparation method thereof
TWI590838B (en) * 2014-04-18 2017-07-11 林信湧 Inhalation-type pharmaceutical composition for diabetes and preparation method thereof
TWI601542B (en) 2014-04-18 2017-10-11 林信湧 Inhalation-type pharmaceutical composition for lung cancer and preparation method thereof
TWI586382B (en) * 2014-04-18 2017-06-11 林信湧 Inhalation-type pharmaceutical composition for kidney disease and preparation method thereof
TWI594772B (en) * 2014-04-18 2017-08-11 林信湧 Inhalation-type pharmaceutical composition for hypertension and preparation method thereof
JP2017143752A (en) * 2016-02-15 2017-08-24 Hack Japan ホールディングス株式会社 supplement
CN109789160A (en) * 2016-07-15 2019-05-21 富氢水技术有限公司 For generating the water of hydrogen-rich and the composition of other products
CA3049278A1 (en) * 2017-01-05 2018-07-12 Warren Lee Apparatus, method, and use for ultrasound mediated microbubble delivery of pharmaceutical compositions
WO2018211474A1 (en) 2017-05-19 2018-11-22 Trudell Medical International Positive expiratory pressure device
USD874064S1 (en) 2018-05-18 2020-01-28 Trudell Medical International Mask
USD903097S1 (en) 2018-05-18 2020-11-24 Trudell Medical International Mask
CA3104889A1 (en) * 2018-07-23 2020-01-30 Nutragenom, Llc Composition and methods for generating and sustaining molecular hydrogen (h2) in aqueous systems
JP6628449B1 (en) * 2018-07-30 2020-01-08 国立大学法人名古屋大学 Composition for controlling or reducing obstructive airway disease
USD893806S1 (en) 2018-11-09 2020-08-18 Trudell Medical Internationl Mask and shroud
JP6667817B1 (en) * 2019-03-13 2020-03-18 住友精化株式会社 Gas composition, method for producing the same, and gas product
JPWO2021090926A1 (en) * 2019-11-08 2021-05-14
CN113318123A (en) * 2020-02-28 2021-08-31 MiZ株式会社 Composition containing molecular hydrogen for preventing and/or improving pneumonia
CN114948990A (en) * 2021-02-22 2022-08-30 上海市肺科医院 Application of magnesium hydride in preparing medicine for preventing and treating acute respiratory distress syndrome
CN114870839B (en) * 2022-02-15 2023-11-10 中国科学院上海硅酸盐研究所 Inorganic nano material with piezoelectric catalysis performance, catalytic hydrogen production nano reactor, and preparation methods and applications thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE407778B (en) * 1977-09-06 1979-04-23 Astra Laekemedel Ab PACKAGING AND PROCEDURE FOR PROTECTION OF MEDICINAL PRODUCTS SOLUTIONS CONTAINING OXIDATIVELY DEGRADABLE SUBSTANCES

Also Published As

Publication number Publication date
JP2000517311A (en) 2000-12-26
HRP970465A2 (en) 1998-08-31
PT921807E (en) 2004-04-30
EP0921807A1 (en) 1999-06-16
WO1998008523A1 (en) 1998-03-05
ES2210585T3 (en) 2004-07-01
EP0921807B1 (en) 2003-11-05
HK1021885A1 (en) 2000-07-14
ATE253372T1 (en) 2003-11-15
DE59710969D1 (en) 2003-12-11
CN1228706A (en) 1999-09-15
CN1191836C (en) 2005-03-09

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