DK0809643T3 - Syntese af (+)-pancratistatin - Google Patents
Syntese af (+)-pancratistatinInfo
- Publication number
- DK0809643T3 DK0809643T3 DK96906378T DK96906378T DK0809643T3 DK 0809643 T3 DK0809643 T3 DK 0809643T3 DK 96906378 T DK96906378 T DK 96906378T DK 96906378 T DK96906378 T DK 96906378T DK 0809643 T3 DK0809643 T3 DK 0809643T3
- Authority
- DK
- Denmark
- Prior art keywords
- pancratistatin
- synthesis
- aziridines
- utilizing
- starting materials
- Prior art date
Links
- VREZDOWOLGNDPW-MYVCAWNPSA-N Pancratistatin Natural products O=C1N[C@H]2[C@H](O)[C@H](O)[C@H](O)[C@H](O)[C@@H]2c2c1c(O)c1OCOc1c2 VREZDOWOLGNDPW-MYVCAWNPSA-N 0.000 title abstract 2
- VREZDOWOLGNDPW-ALTGWBOUSA-N Pancratistatin Chemical compound C1=C2[C@H]3[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O)[C@@H]3NC(=O)C2=C(O)C2=C1OCO2 VREZDOWOLGNDPW-ALTGWBOUSA-N 0.000 title abstract 2
- 230000015572 biosynthetic process Effects 0.000 title abstract 2
- VREZDOWOLGNDPW-UHFFFAOYSA-N pancratistatine Natural products C1=C2C3C(O)C(O)C(O)C(O)C3NC(=O)C2=C(O)C2=C1OCO2 VREZDOWOLGNDPW-UHFFFAOYSA-N 0.000 title abstract 2
- 238000003786 synthesis reaction Methods 0.000 title abstract 2
- 150000001541 aziridines Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000007858 starting material Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Compounds Of Unknown Constitution (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Financial Or Insurance-Related Operations Such As Payment And Settlement (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/389,477 US5627280A (en) | 1995-02-16 | 1995-02-16 | Synthesis of (+)-pancratistatin |
| PCT/US1996/001861 WO1996025415A1 (en) | 1995-02-16 | 1996-02-14 | Synthesis of (+)-pancratistatin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0809643T3 true DK0809643T3 (da) | 2002-02-04 |
Family
ID=23538426
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK96906378T DK0809643T3 (da) | 1995-02-16 | 1996-02-14 | Syntese af (+)-pancratistatin |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5627280A (de) |
| EP (1) | EP0809643B1 (de) |
| AT (1) | ATE207070T1 (de) |
| CA (1) | CA2213253C (de) |
| DE (1) | DE69616029T2 (de) |
| DK (1) | DK0809643T3 (de) |
| ES (1) | ES2166881T3 (de) |
| WO (1) | WO1996025415A1 (de) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002050023A2 (en) * | 2000-12-21 | 2002-06-27 | Arizona Board Of Regents, A Body Corporate Of The State Of Arizona Acting For And On Behalf Of The Arizona State University | Synthesis of pancrastistatin |
| CN105622686B (zh) * | 2016-01-11 | 2021-01-01 | 江苏省中国科学院植物研究所 | 一种生物碱化合物及其制备方法和用途 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1995035303A1 (en) * | 1994-06-17 | 1995-12-28 | Virginia Tech Intellectual Properties, Inc. | Synthesis of conduritol epoxides and aziridines and methods of using such to synthesize higher disaccharides |
-
1995
- 1995-02-16 US US08/389,477 patent/US5627280A/en not_active Expired - Lifetime
-
1996
- 1996-02-14 EP EP96906378A patent/EP0809643B1/de not_active Expired - Lifetime
- 1996-02-14 DK DK96906378T patent/DK0809643T3/da active
- 1996-02-14 CA CA002213253A patent/CA2213253C/en not_active Expired - Lifetime
- 1996-02-14 DE DE69616029T patent/DE69616029T2/de not_active Expired - Lifetime
- 1996-02-14 WO PCT/US1996/001861 patent/WO1996025415A1/en not_active Ceased
- 1996-02-14 ES ES96906378T patent/ES2166881T3/es not_active Expired - Lifetime
- 1996-02-14 AT AT96906378T patent/ATE207070T1/de active
Also Published As
| Publication number | Publication date |
|---|---|
| DE69616029D1 (de) | 2001-11-22 |
| CA2213253C (en) | 2006-07-11 |
| ATE207070T1 (de) | 2001-11-15 |
| CA2213253A1 (en) | 1996-08-22 |
| ES2166881T3 (es) | 2002-05-01 |
| US5627280A (en) | 1997-05-06 |
| EP0809643B1 (de) | 2001-10-17 |
| DE69616029T2 (de) | 2002-06-20 |
| EP0809643A1 (de) | 1997-12-03 |
| WO1996025415A1 (en) | 1996-08-22 |
| MX9706110A (es) | 1997-11-29 |
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