DK0761217T3 - Ready-to-use eye preparation based on indomethacin - Google Patents
Ready-to-use eye preparation based on indomethacinInfo
- Publication number
- DK0761217T3 DK0761217T3 DK96401842T DK96401842T DK0761217T3 DK 0761217 T3 DK0761217 T3 DK 0761217T3 DK 96401842 T DK96401842 T DK 96401842T DK 96401842 T DK96401842 T DK 96401842T DK 0761217 T3 DK0761217 T3 DK 0761217T3
- Authority
- DK
- Denmark
- Prior art keywords
- indomethacin
- ready
- use eye
- preparation based
- eye preparation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Abstract
Ready-to-use eye lotions are aq. solns. contg. indomethacin (I) and the 1-4C alkyl or hydroxyalkyl ethers of beta - or gamma -cyclodextrin (II) derivs., present in a (II):(I) molar ratio of at least 10:1 and a pH of 4-6. (II) is pref. hydroxypropyl- beta -cyclodextrin with a degree of substitution of 0.4. The pH is pref. 4.5-5.5.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9510450A FR2738149B1 (en) | 1995-09-06 | 1995-09-06 | READY-TO-USE INDOMETACIN EYE DROPS |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0761217T3 true DK0761217T3 (en) | 1998-09-28 |
Family
ID=9482314
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK96401842T DK0761217T3 (en) | 1995-09-06 | 1996-08-28 | Ready-to-use eye preparation based on indomethacin |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0761217B1 (en) |
JP (1) | JP4028009B2 (en) |
AT (1) | ATE163851T1 (en) |
CA (1) | CA2183367C (en) |
DE (1) | DE69600185T2 (en) |
DK (1) | DK0761217T3 (en) |
ES (1) | ES2116811T3 (en) |
FR (1) | FR2738149B1 (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0938896A1 (en) * | 1998-01-15 | 1999-09-01 | Novartis AG | Autoclavable pharmaceutical compositions containing a chelating agent |
FR3083234B1 (en) * | 2018-06-29 | 2020-11-27 | Roquette Freres | NEW HYDROXYPROPYL-BETA-CYCLODEXTRINS AND THEIR PREPARATION METHODS |
JP2021529243A (en) * | 2018-06-29 | 2021-10-28 | ロケット フレールRoquette Freres | A novel hydroxypropyl-β-cyclodextrin and a method for producing it |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS57200361A (en) * | 1981-06-03 | 1982-12-08 | Sumitomo Chem Co Ltd | "indomethacin(r)" pharmaceutical with low irritant action |
JPS59152320A (en) * | 1983-02-17 | 1984-08-31 | Takeda Chem Ind Ltd | Aqueous pharmaceutical preparation |
FR2598081B1 (en) * | 1986-04-30 | 1990-02-02 | Chauvin Blache Lab | PROCESS FOR THE PREPARATION OF AN AQUEOUS PHARMACEUTICAL SOLUTION OF AN ACTIVE INGREDIENT CONSTITUTED BY AN ORGANIC ACID |
US5324718A (en) * | 1992-07-14 | 1994-06-28 | Thorsteinn Loftsson | Cyclodextrin/drug complexation |
-
1995
- 1995-09-06 FR FR9510450A patent/FR2738149B1/en not_active Expired - Fee Related
-
1996
- 1996-08-14 CA CA002183367A patent/CA2183367C/en not_active Expired - Lifetime
- 1996-08-27 JP JP22546596A patent/JP4028009B2/en not_active Expired - Lifetime
- 1996-08-28 ES ES96401842T patent/ES2116811T3/en not_active Expired - Lifetime
- 1996-08-28 EP EP96401842A patent/EP0761217B1/en not_active Expired - Lifetime
- 1996-08-28 DK DK96401842T patent/DK0761217T3/en active
- 1996-08-28 DE DE69600185T patent/DE69600185T2/en not_active Expired - Lifetime
- 1996-08-28 AT AT96401842T patent/ATE163851T1/en active
Also Published As
Publication number | Publication date |
---|---|
ATE163851T1 (en) | 1998-03-15 |
CA2183367C (en) | 2005-05-10 |
ES2116811T3 (en) | 1998-07-16 |
EP0761217B1 (en) | 1998-03-11 |
FR2738149B1 (en) | 1997-11-14 |
FR2738149A1 (en) | 1997-03-07 |
JP4028009B2 (en) | 2007-12-26 |
JPH09165334A (en) | 1997-06-24 |
DE69600185T2 (en) | 1998-07-16 |
CA2183367A1 (en) | 1997-03-07 |
EP0761217A1 (en) | 1997-03-12 |
DE69600185D1 (en) | 1998-04-16 |
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