DK0683776T3 - Substituted heteroarylalkylthiopyridines to control Helicobacter bacteria - Google Patents

Substituted heteroarylalkylthiopyridines to control Helicobacter bacteria

Info

Publication number
DK0683776T3
DK0683776T3 DK94907547T DK94907547T DK0683776T3 DK 0683776 T3 DK0683776 T3 DK 0683776T3 DK 94907547 T DK94907547 T DK 94907547T DK 94907547 T DK94907547 T DK 94907547T DK 0683776 T3 DK0683776 T3 DK 0683776T3
Authority
DK
Denmark
Prior art keywords
heteroarylalkylthiopyridines
pct
substituted
helicobacter bacteria
control helicobacter
Prior art date
Application number
DK94907547T
Other languages
Danish (da)
Inventor
Bernhard Kohl
Joerg Senn-Bilfinger
Gerhard Grundler
Wolfgang Opferkuch
Original Assignee
Byk Gulden Lomberg Chem Fab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Byk Gulden Lomberg Chem Fab filed Critical Byk Gulden Lomberg Chem Fab
Application granted granted Critical
Publication of DK0683776T3 publication Critical patent/DK0683776T3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

PCT No. PCT/EP94/00393 Sec. 371 Date Aug. 15, 1995 Sec. 102(e) Date Aug. 15, 1995 PCT Filed Feb. 11, 1994 PCT Pub. No. WO94/19346 PCT Pub. Date Sep. 1, 1994Substituted heteroarylalkylthiopyridines of the formula (I) <IMAGE> (I) are suitable for treating conditions caused by Helicobacter bacteria, in particular the strain Helicobacter pylori.
DK94907547T 1993-02-17 1994-02-11 Substituted heteroarylalkylthiopyridines to control Helicobacter bacteria DK0683776T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH50793 1993-02-17
PCT/EP1994/000393 WO1994019346A1 (en) 1993-02-17 1994-02-11 Substituted heteroarylalkylthiopyridines for controlling helicobacter bacteria

Publications (1)

Publication Number Publication Date
DK0683776T3 true DK0683776T3 (en) 1999-10-18

Family

ID=4188595

Family Applications (1)

Application Number Title Priority Date Filing Date
DK94907547T DK0683776T3 (en) 1993-02-17 1994-02-11 Substituted heteroarylalkylthiopyridines to control Helicobacter bacteria

Country Status (11)

Country Link
US (1) US5587389A (en)
EP (1) EP0683776B1 (en)
JP (1) JPH08507054A (en)
AT (1) ATE178603T1 (en)
AU (1) AU674058B2 (en)
CA (1) CA2156258A1 (en)
DE (1) DE59408087D1 (en)
DK (1) DK0683776T3 (en)
ES (1) ES2132384T3 (en)
GR (1) GR3030288T3 (en)
WO (1) WO1994019346A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0764160A1 (en) * 1994-06-10 1997-03-26 Byk Gulden Lomberg Chemische Fabrik GmbH Thiopyridines for use in the control of helicobacter bacteria
RU2139286C1 (en) * 1994-06-10 1999-10-10 Бык Гульден Ломберг Хемише Фабрик Гмбх Substituted arylalkylthioalkylthiopyridines used for control of bacterium helicobacter
WO1996000224A1 (en) * 1994-06-23 1996-01-04 Byk Gulden Lomberg Chemische Fabrik Gmbh 4-s- and n-substituted 6-alkylpyridines for controlling helicobacter bacteria
WO1998054172A1 (en) * 1997-05-30 1998-12-03 Dr. Reddy's Research Foundation Novel benzimidazole derivatives as antiulcer agents, process for their preparation and pharmaceutical compositions containing them
DE19745692A1 (en) * 1997-07-24 1999-01-28 Bayer Ag Process for the preparation of 2-chloro-benzimidazole derivatives
RU2449805C1 (en) 2011-01-27 2012-05-10 Общество С Ограниченной Ответственностью "Гармония" Peptide pharmaceutical composition, based drug for gastroduodenal diseases caused by helicobacter pylori, and method of using it

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6150978A (en) * 1984-08-16 1986-03-13 Takeda Chem Ind Ltd Pyridine derivative and preparation thereof
FI90544C (en) * 1986-11-13 1994-02-25 Eisai Co Ltd Process for Preparation as Drug Useful 2-Pyridin-2-yl-methylthio- and sulfinyl-1H-benzimidazole derivatives
EP0548103B1 (en) * 1990-09-14 2001-12-05 Byk Gulden Lomberg Chemische Fabrik Gmbh Use of pyridylmethylsulphinyl-1h-benzimidazole derivates in the treatment of illnesses caused by helicobacter bacteria
WO1992012976A1 (en) * 1991-01-16 1992-08-06 Yoshitomi Pharmaceutical Industries, Ltd. Use of pyridine compound as selective drug and novel pyridine compound
US5504082A (en) * 1992-06-01 1996-04-02 Yoshitomi Pharmaceutical Industries, Ltd. Pyridine compound and pharmaceutical compostions

Also Published As

Publication number Publication date
US5587389A (en) 1996-12-24
CA2156258A1 (en) 1994-09-01
GR3030288T3 (en) 1999-09-30
ATE178603T1 (en) 1999-04-15
JPH08507054A (en) 1996-07-30
ES2132384T3 (en) 1999-08-16
EP0683776A1 (en) 1995-11-29
AU6108794A (en) 1994-09-14
AU674058B2 (en) 1996-12-05
DE59408087D1 (en) 1999-05-12
EP0683776B1 (en) 1999-04-07
WO1994019346A1 (en) 1994-09-01

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Legal Events

Date Code Title Description
AHB Application shelved due to non-payment