DK0656773T3 - Use of radical scavengers as immunomodulatory agents in cosmetic and dermatological preparations. - Google Patents

Use of radical scavengers as immunomodulatory agents in cosmetic and dermatological preparations.

Info

Publication number
DK0656773T3
DK0656773T3 DK93918914.8T DK93918914T DK0656773T3 DK 0656773 T3 DK0656773 T3 DK 0656773T3 DK 93918914 T DK93918914 T DK 93918914T DK 0656773 T3 DK0656773 T3 DK 0656773T3
Authority
DK
Denmark
Prior art keywords
cosmetic
radical scavengers
immunomodulatory agents
dermatological preparations
several
Prior art date
Application number
DK93918914.8T
Other languages
Danish (da)
Inventor
Joachim Degwert
Heinrich Gers-Barlag
Loen T Van Den Broeke
V Henegouwen Van Beijersbergen
Original Assignee
Univ Leiden
Beiersdorf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4228455A external-priority patent/DE4228455A1/en
Priority claimed from DE4305788A external-priority patent/DE4305788C2/en
Application filed by Univ Leiden, Beiersdorf Ag filed Critical Univ Leiden
Application granted granted Critical
Publication of DK0656773T3 publication Critical patent/DK0656773T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4973—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom
    • A61K8/498—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with oxygen as the only hetero atom having 6-membered rings or their condensed derivatives, e.g. coumarin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/447—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/676—Ascorbic acid, i.e. vitamin C
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
    • A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers
    • A61K2800/522—Antioxidants; Radical scavengers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/59—Mixtures

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Birds (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Emergency Medicine (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Cosmetic or dermatological compositions for treating and/or preventing UVB radiation-induced immunosuppression are characterised by a therapeutically or cosmetically effective content of one or several radical catchers, as well as by the use of one or several cosmetically or dermatologically acceptable radical catchers for the cosmetic or dermatological treatment and/or prevention of UVBradiation-induced immunosuppression. The radical catchers are chosen from the group of thiols and/or thiol derivatives, that of tocopherols and derivatives thereof, and that consisting of 2,4-0-Furfurylidensorbitol and/or its alkyl ethers.
DK93918914.8T 1992-08-26 1993-08-24 Use of radical scavengers as immunomodulatory agents in cosmetic and dermatological preparations. DK0656773T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4228455A DE4228455A1 (en) 1992-08-26 1992-08-26 Cosmetic and dermatological sunscreen formulations containing thiols and / or thiol derivatives
DE4305788A DE4305788C2 (en) 1993-02-25 1993-02-25 Cosmetic and dermatological formulations to protect the skin against oxidation processes

Publications (1)

Publication Number Publication Date
DK0656773T3 true DK0656773T3 (en) 1997-10-13

Family

ID=25917922

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93918914.8T DK0656773T3 (en) 1992-08-26 1993-08-24 Use of radical scavengers as immunomodulatory agents in cosmetic and dermatological preparations.

Country Status (8)

Country Link
EP (1) EP0656773B1 (en)
JP (1) JPH08506085A (en)
AT (1) ATE150960T1 (en)
AU (1) AU690075B2 (en)
DE (1) DE59306051D1 (en)
DK (1) DK0656773T3 (en)
ES (1) ES2102670T3 (en)
WO (1) WO1994004128A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5645825A (en) * 1995-06-07 1997-07-08 The Procter & Gamble Company Depilatory compositions comprising sulfhydryl compounds
FR2736826B1 (en) * 1995-07-20 1997-08-22 Oreal FILTERING COMPOSITION FOR COSMETIC OR DERMATOLOGICAL USE
FR2736825B1 (en) * 1995-07-20 1997-08-22 Oreal FILTERING COMPOSITION FOR COSMETIC OR DERMATOLOGICAL USE CONTAINING AN IRON CHELATOR
US6284258B1 (en) 1997-12-08 2001-09-04 Arizona Board Of Regents Long-acting, chemical-resistant skin emollients, moisturizers, and strengtheners
DE10014631A1 (en) * 2000-03-24 2001-09-27 Merck Patent Gmbh Treating or preventing UV-induced immunosuppression, using ectoine or its derivatives, is useful in topical care or make-up cosmetic compositions for maintaining the barrier effect of the skin
FR2810548A1 (en) * 2000-06-26 2001-12-28 Oreal USE OF ERGOTHIONEIN AND / OR ITS DERIVATIVES AS AN ANTI-GLYCATION AGENT
US7048910B2 (en) 2000-09-07 2006-05-23 Merck Patent Gmbh Use of ectoine or ectoine derivatives for oral care
DE10214257A1 (en) 2002-03-28 2003-10-16 Merck Patent Gmbh Use of compatible solutes to inhibit the release of ceramides
GB2398497A (en) * 2003-02-19 2004-08-25 Walcom Animal Science Composition for improving immunity of animals
DE102004029239A1 (en) 2004-05-03 2005-12-01 Symrise Gmbh & Co. Kg Benylidene-β-dicarbonyl compounds as new UV absorbers
EP2108369A1 (en) * 2008-04-08 2009-10-14 Giuliani S.P.A. Compounds for the treatment of immunosuppression in the skin caused by aggressive agents

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2331821A1 (en) * 1973-06-22 1975-01-23 Henkel & Cie Gmbh Anti-inflammatory agents for cosmetic preparations
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds
JPS52136925A (en) * 1976-05-12 1977-11-16 Sansho Seiyaku Kk Skin cosmetic
US4248861A (en) * 1979-02-21 1981-02-03 Schutt Steven R Skin treatment methods
DE3685829T2 (en) * 1985-02-04 1992-12-17 Searle & Co HETEROCYCLIC AMIDES.
GB2180153A (en) * 1985-09-10 1987-03-25 Rory Ltd Compositions containing acetylcysteine
DE3542309A1 (en) * 1985-11-29 1987-06-04 Cardona Federico Dr Medicinal antioxidant
US4847267A (en) * 1986-03-17 1989-07-11 Charles Of The Ritz Group Ltd. Skin treatment composition and method
FR2608425B1 (en) * 1986-12-17 1989-04-28 Rofsa Cerd COSMETIC COMPOSITION FOR PARTIAL SELECTIVE DEPIGMENTATION OF THE SKIN AND METHOD FOR THE PRODUCTION THEREOF
IT1205111B (en) * 1987-05-28 1989-03-15 Fitocosmesi & Farma Lab USE OF 2,4-MONOFURFIDYLIDEN-SORBITOL FOR COSMETIC USE
ATE176396T1 (en) * 1987-10-22 1999-02-15 Procter & Gamble LIGHT PROTECTIVE AGENTS CONTAINING CHELATES
US4847072A (en) * 1987-10-22 1989-07-11 The Procter & Gamble Company Photoprotection compositions comprising tocopherol sorbate
DE69013002T2 (en) * 1989-03-14 1995-02-02 Univ Texas UV INDUCED FACTOR FOR IMMUNE SUPPRESSION.
FR2666226B1 (en) * 1990-08-30 1994-10-28 Jean Noel Thorel PROTECTIVE SKIN COMPOSITION.
DE69225631T2 (en) * 1991-02-19 1998-12-17 Nat Food Research Inst Ministr Acylamino acid compounds and process for their preparation
JPH07501540A (en) * 1991-11-25 1995-02-16 リチャードソン、ビックス、インコーポレーテッド Composition for regulating skin wrinkles and/or skin atrophy

Also Published As

Publication number Publication date
DE59306051D1 (en) 1997-05-07
AU4942293A (en) 1994-03-15
EP0656773B1 (en) 1997-04-02
WO1994004128A2 (en) 1994-03-03
ES2102670T3 (en) 1997-08-01
JPH08506085A (en) 1996-07-02
EP0656773A1 (en) 1995-06-14
WO1994004128A3 (en) 1994-07-07
ATE150960T1 (en) 1997-04-15
AU690075B2 (en) 1998-04-23

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