DK0637490T3 - Method and apparatus for making contact lenses - Google Patents
Method and apparatus for making contact lensesInfo
- Publication number
- DK0637490T3 DK0637490T3 DK94810409T DK94810409T DK0637490T3 DK 0637490 T3 DK0637490 T3 DK 0637490T3 DK 94810409 T DK94810409 T DK 94810409T DK 94810409 T DK94810409 T DK 94810409T DK 0637490 T3 DK0637490 T3 DK 0637490T3
- Authority
- DK
- Denmark
- Prior art keywords
- mould
- cavity
- exposure
- contact lenses
- crosslinked
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C31/00—Handling, e.g. feeding of the material to be shaped, storage of plastics material before moulding; Automation, i.e. automated handling lines in plastics processing plants, e.g. using manipulators or robots
- B29C31/04—Feeding of the material to be moulded, e.g. into a mould cavity
- B29C31/041—Feeding of the material to be moulded, e.g. into a mould cavity using filling or dispensing heads placed in closed moulds or in contact with mould walls
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C33/00—Moulds or cores; Details thereof or accessories therefor
- B29C33/02—Moulds or cores; Details thereof or accessories therefor with incorporated heating or cooling means
- B29C33/06—Moulds or cores; Details thereof or accessories therefor with incorporated heating or cooling means using radiation, e.g. electro-magnetic waves, induction heating
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
- B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
- B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
- B29C35/0888—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using transparant moulds
- B29C35/0894—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using transparant moulds provided with masks or diaphragms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C37/00—Component parts, details, accessories or auxiliary operations, not covered by group B29C33/00 or B29C35/00
- B29C37/0003—Discharging moulded articles from the mould
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C37/00—Component parts, details, accessories or auxiliary operations, not covered by group B29C33/00 or B29C35/00
- B29C37/0003—Discharging moulded articles from the mould
- B29C37/0007—Discharging moulded articles from the mould using means operable from outside the mould for moving between mould parts, e.g. robots
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C37/00—Component parts, details, accessories or auxiliary operations, not covered by group B29C33/00 or B29C35/00
- B29C37/005—Compensating volume or shape change during moulding, in general
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
- B29C39/22—Component parts, details or accessories; Auxiliary operations
- B29C39/24—Feeding the material into the mould
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
- B29C39/22—Component parts, details or accessories; Auxiliary operations
- B29C39/36—Removing moulded articles
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C39/00—Shaping by casting, i.e. introducing the moulding material into a mould or between confining surfaces without significant moulding pressure; Apparatus therefor
- B29C39/22—Component parts, details or accessories; Auxiliary operations
- B29C39/42—Casting under special conditions, e.g. vacuum
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
- B29D11/00009—Production of simple or compound lenses
- B29D11/00038—Production of contact lenses
- B29D11/00057—Production of contact lenses characterised by the shape or surface condition of the edge, e.g. flashless, burrless, smooth
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
- B29D11/00009—Production of simple or compound lenses
- B29D11/00038—Production of contact lenses
- B29D11/00125—Auxiliary operations, e.g. removing oxygen from the mould, conveying moulds from a storage to the production line in an inert atmosphere
- B29D11/00134—Curing of the contact lens material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29D—PRODUCING PARTICULAR ARTICLES FROM PLASTICS OR FROM SUBSTANCES IN A PLASTIC STATE
- B29D11/00—Producing optical elements, e.g. lenses or prisms
- B29D11/00009—Production of simple or compound lenses
- B29D11/00432—Auxiliary operations, e.g. machines for filling the moulds
- B29D11/00442—Curing the lens material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C35/00—Heating, cooling or curing, e.g. crosslinking or vulcanising; Apparatus therefor
- B29C35/02—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould
- B29C35/08—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation
- B29C35/0805—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation
- B29C2035/0827—Heating or curing, e.g. crosslinking or vulcanizing during moulding, e.g. in a mould by wave energy or particle radiation using electromagnetic radiation using UV radiation
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C33/00—Moulds or cores; Details thereof or accessories therefor
- B29C33/30—Mounting, exchanging or centering
- B29C33/303—Mounting, exchanging or centering centering mould parts or halves, e.g. during mounting
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2011/00—Optical elements, e.g. lenses, prisms
- B29L2011/0016—Lenses
- B29L2011/0041—Contact lenses
Abstract
A measured-out quantity of a material which can be crosslinked by exposure to a suitable form of energy, in particular UV light (3), is introduced into a two-part mould (1), the cavity (15) of which defines the shape of a moulded part (CL) to be produced. The two mould halves (11, 12) are kept at a small distance from each other, so that there is formed between them a thin annular gap (16), which is in connection with the mould cavity (15) and through which excess material can escape. The crosslinkage is initiated by exposure to the chosen form of energy, exposure being spatially limited to the cavity (15) by suitable masking (21), so that material outside the mould cavity is not crosslinked. In this way, moulded parts which do not require secondary finishing are obtained, and the mould is reusable. The process is suitable in particular, but not exclusively, for the production of contact lenses. <IMAGE>
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP93810515 | 1993-07-19 | ||
CH229993 | 1993-07-29 | ||
CH235093 | 1993-08-06 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0637490T3 true DK0637490T3 (en) | 1999-10-11 |
Family
ID=27173603
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94810409T DK0637490T3 (en) | 1993-07-19 | 1994-07-11 | Method and apparatus for making contact lenses |
Country Status (19)
Country | Link |
---|---|
EP (1) | EP0637490B1 (en) |
JP (1) | JP3257903B2 (en) |
KR (1) | KR100324881B1 (en) |
CN (1) | CN1058658C (en) |
AT (1) | ATE178255T1 (en) |
AU (1) | AU682365B2 (en) |
CA (1) | CA2128158C (en) |
CZ (1) | CZ288697B6 (en) |
DE (1) | DE59408026D1 (en) |
DK (1) | DK0637490T3 (en) |
ES (1) | ES2130384T3 (en) |
FI (1) | FI105792B (en) |
GR (1) | GR3030516T3 (en) |
HU (1) | HU216616B (en) |
IL (1) | IL110281A (en) |
NO (1) | NO310760B1 (en) |
NZ (1) | NZ264031A (en) |
PL (1) | PL304314A1 (en) |
SG (1) | SG49612A1 (en) |
Families Citing this family (45)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ298808A (en) * | 1995-02-02 | 1999-11-29 | Novartis Ag | Process for manufacture of moulded optical articles like contact lenses that are partly coloured or have regions of different colours |
TW349967B (en) * | 1995-02-03 | 1999-01-11 | Novartis Ag | Process for producing contact lenses and a cross-linkable polyvinylalcohol used therefor |
TW360671B (en) * | 1995-02-03 | 1999-06-11 | Novartis Ag | Process for producing mold body and the cross-linkable polymer used therein |
AU4438696A (en) * | 1995-02-03 | 1996-08-21 | Novartis Ag | Crosslinked polymers |
AU7557596A (en) * | 1995-11-09 | 1997-05-29 | Peter Weissman | Method for producing an optical article in a mold sealed under vacuum |
TW448205B (en) * | 1996-05-23 | 2001-08-01 | Novartis Ag | Process for the manufacture of storage-stable hydrogel-moldings |
EP0921922A1 (en) * | 1996-07-24 | 1999-06-16 | Novartis AG | Process for producing mouldings |
EP0936969B1 (en) * | 1996-11-06 | 2002-07-03 | Bausch & Lomb Incorporated | Method and apparatus for separating contact lens mold sections |
DE19706846A1 (en) * | 1997-02-21 | 1998-09-03 | Bodenseewerk Geraetetech | Device for light-initiated chemical crosslinking of material |
AU731550B2 (en) * | 1997-03-25 | 2001-04-05 | Novartis Ag | Molding processes |
US6113817A (en) * | 1997-03-25 | 2000-09-05 | Novartis Ag | Molding processes |
DE19717014A1 (en) * | 1997-04-23 | 1998-10-29 | Inst Mikrotechnik Mainz Gmbh | Process and mold for the production of miniaturized moldings |
AU8534998A (en) * | 1997-05-27 | 1998-12-30 | Novartis Ag | Composite ophthalmic lens |
TW429327B (en) | 1997-10-21 | 2001-04-11 | Novartis Ag | Single mould alignment |
US6997428B1 (en) | 1999-03-31 | 2006-02-14 | Novartis Ag | Contact lens mold |
DE60017550T2 (en) * | 1999-03-31 | 2006-03-30 | Novartis Ag | CASTING FOR THE PRODUCTION OF CONTACT LENSES |
WO2001000393A2 (en) * | 1999-06-25 | 2001-01-04 | Novartis Ag | Uv-illumination device |
GB2355686A (en) * | 1999-10-25 | 2001-05-02 | Hydron Ltd | A method of forming an ophthalmic device |
US6368522B1 (en) * | 2000-01-03 | 2002-04-09 | Johnson & Johnson Vision Care, Inc. | Mold for forming a contact lens and method of preventing formation of small strands of contact lens material during contact lens manufacture |
US6558584B1 (en) | 2000-03-31 | 2003-05-06 | Bausch & Lomb Incorporated | Apparatus and method for handling an ophthalmic lens |
US6737661B2 (en) * | 2000-08-17 | 2004-05-18 | Novartis Ag | Pre-treatment of molds |
ATE526135T1 (en) | 2001-03-26 | 2011-10-15 | Novartis Ag | MOLD AND METHOD FOR PRODUCING OPTHALMIC LENSES |
US20030031548A1 (en) * | 2001-08-09 | 2003-02-13 | Parell Phillip King | Rigid vacuum tip |
US6997693B2 (en) * | 2001-10-19 | 2006-02-14 | Novartis Ag | Casting mold half and casting mold for producing contact lenses |
EP1654543B1 (en) | 2003-08-07 | 2010-07-07 | EyeSense AG | Ophthalmic sensor |
US20050056954A1 (en) * | 2003-09-12 | 2005-03-17 | Devlin Brian Gerrard | Method for making contact lenses |
DE102004010648B4 (en) * | 2004-02-26 | 2008-12-04 | Jenoptik Laser, Optik, Systeme Gmbh | Radiation-permeable mold half for a mold |
US8003024B2 (en) * | 2006-09-18 | 2011-08-23 | Coopervision International Holding Company, Lp | Polyolefin contact lens molds and uses thereof |
CN101801652B (en) * | 2007-04-23 | 2014-10-29 | 数字光学公司 | Mass production of micro-optical devices, corresponding tools, and resultant structures |
DE102007024642A1 (en) | 2007-05-24 | 2008-11-27 | Eyesense Ag | Hydrogel implant for sensor of metabolites on the eye |
AU2008343162B2 (en) * | 2007-12-20 | 2012-02-23 | Alcon Inc. | Method for making contact lenses |
CN103313843B (en) * | 2010-11-26 | 2017-03-22 | 日柔有限公司 | contact lens manufacturing method |
CN103465410B (en) * | 2012-06-06 | 2015-12-09 | 视霸光学股份有限公司 | Ultrasonic stripper apparatus and be applied to and manufacture the method for contact lenses |
DE102013207243B4 (en) | 2013-04-22 | 2019-10-02 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | DEVICE AND METHOD FOR PRODUCING A STRUCTURE OF CURABLE MATERIAL BY IMPREGNATION |
DE102013220097B4 (en) * | 2013-10-02 | 2017-05-11 | Smp Deutschland Gmbh | Forming tool and forming process for this purpose |
CN105745056B (en) * | 2013-11-14 | 2018-09-04 | 柯尼卡美能达株式会社 | The manufacturing method and optical element of optical element |
US10022925B2 (en) * | 2013-12-20 | 2018-07-17 | Novartis Ag | Reusable castings molds |
CN105204180B (en) * | 2015-09-23 | 2018-01-26 | 江苏视客光学眼镜有限公司 | The manufacture method and device of compound spectacle glass |
EP3390025B1 (en) * | 2015-12-17 | 2023-09-06 | Alcon Inc. | Reusable lens molds and methods of use thereof |
KR101825078B1 (en) * | 2016-05-09 | 2018-02-02 | (주)티이바이오스 | Mold for manufacturing artificial cornea and method of manufacturing artificial cornea using the same |
FR3051136A1 (en) * | 2016-05-10 | 2017-11-17 | Roctool | METHOD AND DEVICE FOR HEATING A MOLD |
EP3867677A4 (en) * | 2018-10-16 | 2021-12-22 | Magic Leap, Inc. | Methods and apparatuses for casting polymer products |
CN111483099B (en) * | 2019-01-25 | 2022-05-10 | 优你康光学股份有限公司 | Mold for demolding contact lenses and method thereof |
CN109895311B (en) * | 2019-04-19 | 2021-03-02 | 浙江宝祥工贸有限公司 | Cylindrical forming die |
CN110435057A (en) * | 2019-08-20 | 2019-11-12 | 瑞声科技(新加坡)有限公司 | For forming the mold of wafer eyeglass |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4113224A (en) * | 1975-04-08 | 1978-09-12 | Bausch & Lomb Incorporated | Apparatus for forming optical lenses |
EP0226123A3 (en) * | 1985-12-03 | 1988-08-10 | Matsushita Electric Industrial Co., Ltd. | Method for producing transparent plastic article |
JPS6334108A (en) * | 1986-07-30 | 1988-02-13 | Hitachi Ltd | Manufacture of substrate for optical disc and device therefor |
ES2096846T3 (en) * | 1988-11-02 | 1997-03-16 | British Tech Group | MOLDING AND CONTAINER CONTACT LENSES. |
DE69113392T2 (en) * | 1990-10-30 | 1996-05-15 | Minnesota Mining & Mfg | Procedures for networking conspicuous objects. |
-
1994
- 1994-07-11 SG SG9601017A patent/SG49612A1/en unknown
- 1994-07-11 EP EP94810409A patent/EP0637490B1/en not_active Expired - Lifetime
- 1994-07-11 DE DE59408026T patent/DE59408026D1/en not_active Expired - Lifetime
- 1994-07-11 AT AT94810409T patent/ATE178255T1/en not_active IP Right Cessation
- 1994-07-11 DK DK94810409T patent/DK0637490T3/en active
- 1994-07-11 ES ES94810409T patent/ES2130384T3/en not_active Expired - Lifetime
- 1994-07-11 IL IL11028194A patent/IL110281A/en not_active IP Right Cessation
- 1994-07-13 JP JP16112694A patent/JP3257903B2/en not_active Expired - Lifetime
- 1994-07-15 FI FI943375A patent/FI105792B/en not_active IP Right Cessation
- 1994-07-15 AU AU67538/94A patent/AU682365B2/en not_active Expired
- 1994-07-15 HU HU9402122A patent/HU216616B/en not_active IP Right Cessation
- 1994-07-15 CA CA002128158A patent/CA2128158C/en not_active Expired - Lifetime
- 1994-07-15 PL PL94304314A patent/PL304314A1/en unknown
- 1994-07-18 CN CN94108392A patent/CN1058658C/en not_active Expired - Lifetime
- 1994-07-18 NZ NZ264031A patent/NZ264031A/en unknown
- 1994-07-18 KR KR1019940017235A patent/KR100324881B1/en not_active IP Right Cessation
- 1994-07-18 CZ CZ19941726A patent/CZ288697B6/en not_active IP Right Cessation
- 1994-07-18 NO NO19942691A patent/NO310760B1/en not_active IP Right Cessation
-
1999
- 1999-06-15 GR GR990401591T patent/GR3030516T3/en unknown
Also Published As
Publication number | Publication date |
---|---|
FI943375A0 (en) | 1994-07-15 |
HU9402122D0 (en) | 1994-09-28 |
EP0637490A1 (en) | 1995-02-08 |
PL304314A1 (en) | 1995-01-23 |
IL110281A (en) | 1998-10-30 |
SG49612A1 (en) | 2003-03-18 |
CN1108999A (en) | 1995-09-27 |
JPH0768563A (en) | 1995-03-14 |
CA2128158C (en) | 1999-01-19 |
NO310760B1 (en) | 2001-08-27 |
FI105792B (en) | 2000-10-13 |
KR950002966A (en) | 1995-02-16 |
CZ172694A3 (en) | 1995-11-15 |
NO942691D0 (en) | 1994-07-18 |
CA2128158A1 (en) | 1995-01-20 |
HU216616B (en) | 1999-07-28 |
GR3030516T3 (en) | 1999-10-29 |
HUT69316A (en) | 1995-09-28 |
ATE178255T1 (en) | 1999-04-15 |
AU682365B2 (en) | 1997-10-02 |
CN1058658C (en) | 2000-11-22 |
EP0637490B1 (en) | 1999-03-31 |
IL110281A0 (en) | 1994-10-21 |
DE59408026D1 (en) | 1999-05-06 |
FI943375A (en) | 1995-01-20 |
KR100324881B1 (en) | 2002-10-25 |
NZ264031A (en) | 1996-03-26 |
ES2130384T3 (en) | 1999-07-01 |
AU6753894A (en) | 1995-01-27 |
JP3257903B2 (en) | 2002-02-18 |
NO942691L (en) | 1995-01-20 |
CZ288697B6 (en) | 2001-08-15 |
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