DK0614891T3 - Process for the preparation of 2-substituted 5-chloroimidazole-4-carbaldehydes - Google Patents
Process for the preparation of 2-substituted 5-chloroimidazole-4-carbaldehydesInfo
- Publication number
- DK0614891T3 DK0614891T3 DK94103714T DK94103714T DK0614891T3 DK 0614891 T3 DK0614891 T3 DK 0614891T3 DK 94103714 T DK94103714 T DK 94103714T DK 94103714 T DK94103714 T DK 94103714T DK 0614891 T3 DK0614891 T3 DK 0614891T3
- Authority
- DK
- Denmark
- Prior art keywords
- substituted
- preparation
- carbaldehydes
- chloroimidazole
- optionally
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/68—Halogen atoms
Abstract
The optionally 2-substituted 5-chloroimidazoles of the general formula <IMAGE> are novel intermediates for the preparation of antihypertensive pharmaceuticals (vasodepressants) or of herbicidally active compounds. There are described a process for the preparation of these intermediates and a novel process for the further reaction of optionally 2-substituted 5-chloroimidazoles of the general formula I in which R<1> is hydrogen to give the optionally 2-substituted 5-chloroimidazole-4-carbaldehydes of the general formula <IMAGE>
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH74893 | 1993-03-12 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0614891T3 true DK0614891T3 (en) | 1999-08-30 |
Family
ID=4194282
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94103636.0T DK0614890T3 (en) | 1993-03-12 | 1994-03-09 | Process for preparing optionally 2-substituted 5-chloroimidazoles. |
DK94103714T DK0614891T3 (en) | 1993-03-12 | 1994-03-10 | Process for the preparation of 2-substituted 5-chloroimidazole-4-carbaldehydes |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94103636.0T DK0614890T3 (en) | 1993-03-12 | 1994-03-09 | Process for preparing optionally 2-substituted 5-chloroimidazoles. |
Country Status (9)
Country | Link |
---|---|
EP (2) | EP0614890B1 (en) |
JP (1) | JP3716434B2 (en) |
KR (1) | KR100362353B1 (en) |
AT (2) | ATE157655T1 (en) |
CA (2) | CA2473422C (en) |
DE (2) | DE59403903D1 (en) |
DK (2) | DK0614890T3 (en) |
ES (2) | ES2108894T3 (en) |
HU (2) | HU213387B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2175420C (en) * | 1995-05-17 | 2007-04-10 | Gareth Griffiths | Process for the preparation of optionally 2-substituted 5-chloroimidazole-4-carbaldehydes |
JP4103149B2 (en) * | 1996-01-05 | 2008-06-18 | ロンザ リミテッド | Process for producing 2-substituted 5-chloroimidazole-4-carbaldehyde |
KR101035559B1 (en) * | 2009-06-02 | 2011-05-19 | 한국화학연구원 | Pharmaceutical composition for the prevention or treatment of osteoporosis or obesity comprising a chloroimidazole derivative or a pharmaceutically acceptable salt thereof as an active ingredient |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3409606A (en) * | 1965-12-30 | 1968-11-05 | American Cyanamid Co | Halogenated chloroimidazole compounds |
IL53783A (en) * | 1977-02-03 | 1982-08-31 | American Cyanamid Co | Imidazo(1,5-d)-as-triazine-4 (3h)-(thi)one derivatives,their preparation and pharmaceutical compositions containing them |
JPS5671074A (en) * | 1979-11-12 | 1981-06-13 | Takeda Chem Ind Ltd | 1,2-disubstituted-4-halogenoimidazole-5-acetic acid derivative |
DE3145927A1 (en) * | 1981-11-20 | 1983-06-01 | Basf Ag, 6700 Ludwigshafen | 4(5)-Methyl-5(4)-chloroimidazole and process for its preparation |
DE3330192A1 (en) * | 1983-08-20 | 1985-03-07 | Basf Ag, 6700 Ludwigshafen | 4-ALKYLIMIDAZOLE DERIVATIVES, THEIR PRODUCTION AND USE |
JPS62238383A (en) * | 1986-04-07 | 1987-10-19 | Chiyoda Kagaku Kenkyusho:Kk | Anticorrosive |
CA1334092C (en) * | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
JPH02262562A (en) * | 1988-10-20 | 1990-10-25 | Ishihara Sangyo Kaisha Ltd | Imidazole compound |
PT95899A (en) * | 1989-11-17 | 1991-09-13 | Glaxo Group Ltd | PROCESS FOR THE PREPARATION OF INDOLE DERIVATIVES |
JPH0426678A (en) * | 1990-05-18 | 1992-01-29 | Nippon Synthetic Chem Ind Co Ltd:The | Production of imidazole-4-chloro-5-carbaldehyde derivative |
US5126342A (en) * | 1990-10-01 | 1992-06-30 | Merck & Co., Inc. | Imidazole angiotensin ii antagonists incorporating acidic functional groups |
EP0505098A1 (en) * | 1991-03-19 | 1992-09-23 | Merck & Co. Inc. | Imidazole derivatives bearing acidic functional groups as angiotensin II antagonists |
RU2103262C1 (en) * | 1992-07-16 | 1998-01-27 | Лонца АГ Гампель/Валлис | Method for production of 2-substituted 5-chloroimidazole-4-carbaldehydes |
-
1994
- 1994-03-09 ES ES94103636T patent/ES2108894T3/en not_active Expired - Lifetime
- 1994-03-09 AT AT94103636T patent/ATE157655T1/en active
- 1994-03-09 DK DK94103636.0T patent/DK0614890T3/en active
- 1994-03-09 EP EP94103636A patent/EP0614890B1/en not_active Expired - Lifetime
- 1994-03-09 DE DE59403903T patent/DE59403903D1/en not_active Expired - Lifetime
- 1994-03-10 AT AT94103714T patent/ATE175199T1/en active
- 1994-03-10 EP EP94103714A patent/EP0614891B1/en not_active Expired - Lifetime
- 1994-03-10 DK DK94103714T patent/DK0614891T3/en active
- 1994-03-10 DE DE59407547T patent/DE59407547D1/en not_active Expired - Lifetime
- 1994-03-10 ES ES94103714T patent/ES2127845T3/en not_active Expired - Lifetime
- 1994-03-11 JP JP04081394A patent/JP3716434B2/en not_active Expired - Fee Related
- 1994-03-11 HU HU9400736A patent/HU213387B/en not_active IP Right Cessation
- 1994-03-11 KR KR1019940004757A patent/KR100362353B1/en not_active IP Right Cessation
- 1994-03-11 HU HU9701565A patent/HU219708B/en not_active IP Right Cessation
- 1994-03-14 CA CA002473422A patent/CA2473422C/en not_active Expired - Fee Related
- 1994-03-14 CA CA002117209A patent/CA2117209C/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
EP0614890B1 (en) | 1997-09-03 |
CA2473422A1 (en) | 1994-09-13 |
EP0614890A3 (en) | 1995-01-11 |
JPH072789A (en) | 1995-01-06 |
ATE157655T1 (en) | 1997-09-15 |
CA2473422C (en) | 2007-05-22 |
HUT66633A (en) | 1994-12-28 |
EP0614891A3 (en) | 1995-05-03 |
DE59407547D1 (en) | 1999-02-11 |
CA2117209A1 (en) | 1994-09-13 |
ATE175199T1 (en) | 1999-01-15 |
JP3716434B2 (en) | 2005-11-16 |
HU219708B (en) | 2001-06-28 |
EP0614891B1 (en) | 1998-12-30 |
EP0614891A2 (en) | 1994-09-14 |
HU9400736D0 (en) | 1994-06-28 |
HU213387B (en) | 1997-05-28 |
KR100362353B1 (en) | 2003-03-19 |
DE59403903D1 (en) | 1997-10-09 |
DK0614890T3 (en) | 1997-10-13 |
ES2108894T3 (en) | 1998-01-01 |
HU9701565D0 (en) | 1997-11-28 |
EP0614890A2 (en) | 1994-09-14 |
ES2127845T3 (en) | 1999-05-01 |
CA2117209C (en) | 2005-05-31 |
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