DK0555446T3 - Use of antagonists or partial agonists at the 5-HT1a receptor for the treatment and prevention of cognitive tests - Google Patents
Use of antagonists or partial agonists at the 5-HT1a receptor for the treatment and prevention of cognitive testsInfo
- Publication number
- DK0555446T3 DK0555446T3 DK92918251T DK92918251T DK0555446T3 DK 0555446 T3 DK0555446 T3 DK 0555446T3 DK 92918251 T DK92918251 T DK 92918251T DK 92918251 T DK92918251 T DK 92918251T DK 0555446 T3 DK0555446 T3 DK 0555446T3
- Authority
- DK
- Denmark
- Prior art keywords
- antagonists
- prevention
- treatment
- partial agonists
- ht1a receptor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Abstract
The description relates to the novel use of antagonists or partial agonists on the 5HT1a? receptor to produce a medicament for the treatment and prevention of cognitive and pharmaceuticals containing these compounds.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4135551A DE4135551A1 (en) | 1991-08-31 | 1991-08-31 | USE OF ANTAGONISTS OR PARTIAL AGONISTS ON THE 5-HT1A RECEPTOR TO TREAT AND PREVENT COGNITIVE DISORDERS |
PCT/DE1992/000720 WO1993004681A1 (en) | 1991-08-31 | 1992-08-28 | Use of antagonists or partial agonists on the 5-ht1a receptor for the treatment and prevention of cognitive disorders |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0555446T3 true DK0555446T3 (en) | 2000-01-31 |
Family
ID=6443608
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK92918251T DK0555446T3 (en) | 1991-08-31 | 1992-08-28 | Use of antagonists or partial agonists at the 5-HT1a receptor for the treatment and prevention of cognitive tests |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0555446B1 (en) |
JP (1) | JPH06501713A (en) |
AT (1) | ATE182467T1 (en) |
CA (1) | CA2093009A1 (en) |
DE (2) | DE4135551A1 (en) |
DK (1) | DK0555446T3 (en) |
ES (1) | ES2135412T3 (en) |
GR (1) | GR3031514T3 (en) |
HU (1) | HUT63331A (en) |
WO (1) | WO1993004681A1 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9223153D0 (en) * | 1992-11-05 | 1992-12-16 | Wyeth John & Brother Ltd | Piperazine derivatives |
US5484788A (en) * | 1993-03-26 | 1996-01-16 | Beth Israel Hospital Association | Buspirone as a systemic immunosuppressant |
EP0710481A1 (en) * | 1994-11-02 | 1996-05-08 | Duphar International Research B.V | Use of flesinoxan for cognition enhancement |
US5637314A (en) * | 1995-06-07 | 1997-06-10 | Beth Israel Deaconess Medical Center, Inc. | Topical and systemic application of buspirone or derivatives thereof for treating atopic dermatitis |
EP1075486A1 (en) | 1998-05-06 | 2001-02-14 | Duke University | Method of treating bladder and lower urinary tract syndromes |
US7053092B2 (en) | 2001-01-29 | 2006-05-30 | Otsuka Pharmaceutical Co., Ltd. | 5-HT1a receptor subtype agonist |
US8703772B2 (en) | 2001-09-25 | 2014-04-22 | Otsuka Pharmaceutical Co., Ltd. | Low hygroscopic aripiprazole drug substance and processes for the preparation thereof |
AR033485A1 (en) | 2001-09-25 | 2003-12-26 | Otsuka Pharma Co Ltd | MEDICINAL SUBSTANCE OF ARIPIPRAZOL OF LOW HYGROSCOPICITY AND PROCESS FOR THE PREPARATION OF THE SAME |
GT200600414A (en) | 2005-09-12 | 2007-09-20 | PIPERAZINE COMPOSITE GLUCURANATE SALT | |
TW200800306A (en) | 2005-09-12 | 2008-01-01 | Wyeth Corp | Sustained-release formulation and uses thereof |
GT200600416A (en) | 2005-09-12 | 2007-09-20 | SALTS SALCILATO AND GENTISATO OF A COMPOSITE OF PIPERAZINA | |
CN102918031A (en) | 2010-05-28 | 2013-02-06 | 通用电气健康护理有限公司 | Radiolabeled compounds and methods thereof |
GB201112987D0 (en) | 2011-07-28 | 2011-09-14 | Ge Healthcare Ltd | Novel compound |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2355502A1 (en) * | 1976-06-23 | 1978-01-20 | Roussel Uclaf | APPLICATION AS A MEDICINAL PRODUCT OF A DERIVATIVE OF PIPERAZINE AND ITS SALTS |
US4423049A (en) * | 1981-12-28 | 1983-12-27 | Mead Johnson & Company | 2-[4-[(4,4-Dialkyl-2,6-piperidinedion-1-yl)butyl]-1-piperazinyl]pyrimidines |
US4897399A (en) * | 1988-04-20 | 1990-01-30 | Ciba-Geigy Corp. | Heterotertracyclic lactam derivatives, pharmaceutical compositions, and method of treating impaired memory and learning |
GB2222768B (en) * | 1988-06-17 | 1992-01-22 | Nat Res Dev | Analgesic compounds and compositions |
US4902687A (en) * | 1989-03-27 | 1990-02-20 | Eli Lilly And Company | Excitatory amino acid receptor antagonists |
DE4039631A1 (en) * | 1990-12-12 | 1992-06-17 | Troponwerke Gmbh & Co Kg | Neuro-protective combination for treating cerebral ischaemia - contains a 5-HT1A receptor agonist and 5-HT2 receptor antagonist |
-
1991
- 1991-08-31 DE DE4135551A patent/DE4135551A1/en not_active Withdrawn
-
1992
- 1992-08-28 ES ES92918251T patent/ES2135412T3/en not_active Expired - Lifetime
- 1992-08-28 DE DE59209728T patent/DE59209728D1/en not_active Revoked
- 1992-08-28 AT AT92918251T patent/ATE182467T1/en not_active IP Right Cessation
- 1992-08-28 WO PCT/DE1992/000720 patent/WO1993004681A1/en not_active Application Discontinuation
- 1992-08-28 EP EP92918251A patent/EP0555446B1/en not_active Revoked
- 1992-08-28 CA CA002093009A patent/CA2093009A1/en not_active Abandoned
- 1992-08-28 HU HU9301250A patent/HUT63331A/en unknown
- 1992-08-28 JP JP5504830A patent/JPH06501713A/en active Pending
- 1992-08-28 DK DK92918251T patent/DK0555446T3/en active
-
1999
- 1999-10-13 GR GR990402609T patent/GR3031514T3/en unknown
Also Published As
Publication number | Publication date |
---|---|
HUT63331A (en) | 1993-08-30 |
ATE182467T1 (en) | 1999-08-15 |
GR3031514T3 (en) | 2000-01-31 |
CA2093009A1 (en) | 1993-03-01 |
JPH06501713A (en) | 1994-02-24 |
EP0555446B1 (en) | 1999-07-28 |
WO1993004681A1 (en) | 1993-03-18 |
DE4135551A1 (en) | 1993-03-04 |
ES2135412T3 (en) | 1999-11-01 |
EP0555446A1 (en) | 1993-08-18 |
HU9301250D0 (en) | 1993-07-28 |
DE59209728D1 (en) | 1999-09-02 |
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