DK0541593T3 - Cyclopentene derivatives, process for their preparation and pharmaceutical use of the derivatives - Google Patents

Cyclopentene derivatives, process for their preparation and pharmaceutical use of the derivatives

Info

Publication number
DK0541593T3
DK0541593T3 DK91912996.5T DK91912996T DK0541593T3 DK 0541593 T3 DK0541593 T3 DK 0541593T3 DK 91912996 T DK91912996 T DK 91912996T DK 0541593 T3 DK0541593 T3 DK 0541593T3
Authority
DK
Denmark
Prior art keywords
derivatives
pharmaceutical use
preparation
cyclopentene
formula
Prior art date
Application number
DK91912996.5T
Other languages
Danish (da)
Inventor
Karl-Heinz Thierauch
Ulrich Klar
Helmut Vorbrueggen
Peter Verhallen
Hartmut Rehwinkel
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Application granted granted Critical
Publication of DK0541593T3 publication Critical patent/DK0541593T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/36—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Immunology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The invention relates to cyclopentane derivatives of formula (I) in which there is a double bond between the carbon atoms of centres a-b or b-c, and their salts with physiologically tolerable bases, and $g(a), $g(b) or $g(g)-cyclodextrin clathrates and the liposome-encapsulated compounds of formula (I), process of producing them and their pharmaceutical use.
DK91912996.5T 1990-07-27 1991-07-22 Cyclopentene derivatives, process for their preparation and pharmaceutical use of the derivatives DK0541593T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4024345A DE4024345A1 (en) 1990-07-27 1990-07-27 CYCLOPENTE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR PHARMACEUTICAL USE

Publications (1)

Publication Number Publication Date
DK0541593T3 true DK0541593T3 (en) 1996-02-05

Family

ID=6411401

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91912996.5T DK0541593T3 (en) 1990-07-27 1991-07-22 Cyclopentene derivatives, process for their preparation and pharmaceutical use of the derivatives

Country Status (14)

Country Link
EP (1) EP0541593B1 (en)
JP (1) JPH05509090A (en)
AT (1) ATE127788T1 (en)
AU (1) AU8227491A (en)
CA (1) CA2088159A1 (en)
DE (2) DE4024345A1 (en)
DK (1) DK0541593T3 (en)
ES (1) ES2080956T3 (en)
GR (1) GR3018360T3 (en)
IE (1) IE73476B1 (en)
IL (1) IL98969A0 (en)
PT (1) PT98465B (en)
WO (1) WO1992002494A1 (en)
ZA (1) ZA915903B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2890899A (en) * 1998-03-13 1999-09-27 Pozen, Inc. Prophylaxis and treatment of migraine headaches with thromboxane synthetase inhibitors and/or receptor antagonists

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792803A (en) * 1971-12-17 1973-03-30 Erba Carlo Spa OPTICALLY ACTIVE 8,12-DIISOPROSTANOIC ACID DERIVATIVES, THEIR PREPARATION AND COMPOSITIONS CONTAINING
US3933904A (en) * 1974-09-13 1976-01-20 American Home Products Corporation 11,15-Dihydroxy-9,13-prostadienoic acid
NL7414650A (en) * 1974-11-11 1976-05-13 Akzo Nv NEW PROSTAGLANDIN ANALOGA.
GB1539268A (en) * 1976-12-23 1979-01-31 Ici Ltd Prostane derivatives
DE3125271A1 (en) * 1981-06-24 1983-01-13 Schering Ag, 1000 Berlin Und 4619 Bergkamen (DELTA) (UP ARROW) 8 (UP ARROW), (UP ARROW) 9 (UP ARROW) PROSTAGLAND IN DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS MEDICINAL PRODUCTS
JPH0798795B2 (en) * 1987-05-08 1995-10-25 塩野義製薬株式会社 Sulfonamide-substituted unsaturated fatty acid
DE3923798A1 (en) * 1989-07-14 1991-01-17 Schering Ag (DELTA) (UP ARROW) 8 (UP ARROW) AND (DELTA) (UP ARROW) 9 (UP ARROW) PROSTAGLANDIN DERIVATIVES, METHODS OF THEIR PRODUCTION AND THEIR PHARMACEUTICAL USE

Also Published As

Publication number Publication date
GR3018360T3 (en) 1996-03-31
EP0541593A1 (en) 1993-05-19
AU8227491A (en) 1992-03-02
ATE127788T1 (en) 1995-09-15
PT98465B (en) 1997-10-31
IL98969A0 (en) 1992-07-15
ES2080956T3 (en) 1996-02-16
PT98465A (en) 1992-05-29
IE912655A1 (en) 1992-01-29
EP0541593B1 (en) 1995-09-13
ZA915903B (en) 1992-04-29
WO1992002494A1 (en) 1992-02-20
DE59106490D1 (en) 1995-10-19
JPH05509090A (en) 1993-12-16
CA2088159A1 (en) 1992-01-28
IE73476B1 (en) 1997-06-04
DE4024345A1 (en) 1992-01-30

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