DK0536036T3 - Tocoferol-analoger med cardioprotektiv virkning. - Google Patents

Tocoferol-analoger med cardioprotektiv virkning.

Info

Publication number
DK0536036T3
DK0536036T3 DK92402656.0T DK92402656T DK0536036T3 DK 0536036 T3 DK0536036 T3 DK 0536036T3 DK 92402656 T DK92402656 T DK 92402656T DK 0536036 T3 DK0536036 T3 DK 0536036T3
Authority
DK
Denmark
Prior art keywords
tocoferol
analogues
cardioprotective effect
cardioprotective
benzopyrans
Prior art date
Application number
DK92402656.0T
Other languages
Danish (da)
English (en)
Inventor
Martin J Grisar
Frank Bolkenius
Margaret A Petty
Original Assignee
Merrell Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Pharma Inc filed Critical Merrell Pharma Inc
Application granted granted Critical
Publication of DK0536036T3 publication Critical patent/DK0536036T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/6552Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring
    • C07F9/65522Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a six-membered ring condensed with carbocyclic rings or carbocyclic ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Inspection Of Paper Currency And Valuable Securities (AREA)
  • Credit Cards Or The Like (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Noodles (AREA)
  • Cosmetics (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Fire-Detection Mechanisms (AREA)
  • Absorbent Articles And Supports Therefor (AREA)
  • Saccharide Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DK92402656.0T 1991-10-02 1992-09-29 Tocoferol-analoger med cardioprotektiv virkning. DK0536036T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP91402630A EP0535283A1 (en) 1991-10-02 1991-10-02 Cardioprotective tocopherol analogs

Publications (1)

Publication Number Publication Date
DK0536036T3 true DK0536036T3 (da) 1998-03-16

Family

ID=8208620

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92402656.0T DK0536036T3 (da) 1991-10-02 1992-09-29 Tocoferol-analoger med cardioprotektiv virkning.

Country Status (17)

Country Link
EP (2) EP0535283A1 (cs)
JP (1) JP3230699B2 (cs)
KR (1) KR100253108B1 (cs)
AT (1) ATE163421T1 (cs)
AU (1) AU652077B2 (cs)
CA (1) CA2079289C (cs)
DE (1) DE69224501T2 (cs)
DK (1) DK0536036T3 (cs)
ES (1) ES2115656T3 (cs)
FI (1) FI105552B (cs)
GR (1) GR3026242T3 (cs)
HU (1) HU215123B (cs)
IL (1) IL103305A0 (cs)
NO (1) NO923840L (cs)
NZ (1) NZ244549A (cs)
TW (1) TW224970B (cs)
ZA (1) ZA927429B (cs)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5721233A (en) * 1992-04-06 1998-02-24 Merrell Pharmaceuticals Inc. Derivatives of 2,3-dihydro benzofuranols
US5510373A (en) * 1992-04-06 1996-04-23 Merrell Pharmaceuticals Inc. Cardioprotective agents
US5545660A (en) * 1992-04-07 1996-08-13 Merrell Pharmaceuticals Inc. Hydrazide derivatives of 3,4-dihydro-2H-1-benzopyrans
JP4590523B2 (ja) * 1997-11-25 2010-12-01 アンティポディーン ファーマシューティカルズ インコーポレイテッド ミトコンドリアを標的とする抗酸化剤
AUPR549901A0 (en) 2001-06-06 2001-07-12 Vital Health Sciences Pty Ltd Topical formulation containing tocopheryl phosphates
WO2003011303A1 (en) 2001-07-27 2003-02-13 Vital Health Sciences Pty Ltd Dermal therapy using phosphate derivatives of electron transfer agents
EP1374882B1 (de) * 2002-06-19 2008-10-01 Cognis IP Management GmbH Verwendung von Wirkstoffgemischen zur Herstellung eines Medikamentes gegen rheumatische Arthritis
AU2002950713A0 (en) 2002-08-09 2002-09-12 Vital Health Sciences Pty Ltd Carrier
US7888334B2 (en) 2003-08-22 2011-02-15 Antipodean Pharmaceuticals, Inc. Mitoquinone derivatives used as mitochondrially targeted antioxidants
SG145715A1 (en) 2003-08-22 2008-09-29 Antipodean Pharmaceuticals Inc Mitoquinone derivatives used as mitochondrially targeted antioxidants
US7514461B2 (en) 2003-09-19 2009-04-07 Edison Pharmaceuticals, Inc. Chroman derivatives
DE602005025979D1 (de) 2004-03-03 2011-03-03 Vital Health Sciences Pty Ltd Alkaloid-formulierungen
BRPI0613346A2 (pt) 2005-06-17 2011-01-04 Vital Health Sciences Pty Ltd veìculo para a administração de compostos biologicamente ativos, uso de um ou mais álcoois c1-c4,polióis e polìmeros dos mesmos, água e um ou mais derivados de di- e/ou mono-fosfato do agente de transferência de elétrons ou complexos dos mesmos, processo para a preparação do veìculo, formulação, método de preparação da formulação, método de administração de compostos biologicamente ativos
US7813042B2 (en) 2005-09-12 2010-10-12 Sharp Kabushiki Kaisha Multiple-view directional display
US8687273B2 (en) 2006-09-07 2014-04-01 Sharp Kabushiki Kaisha Image display device, electronic device, and parallax barrier element
US10071030B2 (en) 2010-02-05 2018-09-11 Phosphagenics Limited Carrier comprising non-neutralised tocopheryl phosphate
EP2552486B1 (en) 2010-03-30 2020-08-12 Phosphagenics Limited Transdermal delivery patch
EP2685992A4 (en) 2011-03-15 2014-09-10 Phosphagenics Ltd AMINOCHINOLINE AS A KINASEHEMMER
AU2016367708B2 (en) 2015-12-09 2022-07-14 Phosphagenics Limited Pharmaceutical formulation
US20190330260A1 (en) 2016-12-21 2019-10-31 Avecho Biotechnology Limited Process

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS62205091A (ja) * 1986-03-04 1987-09-09 Senjiyu Seiyaku Kk 新規なリン酸ジエステルならびにその塩、その製造法およびそれを含有する製剤
CA2002649C (en) * 1988-11-14 2000-06-06 Margaret Petty Cardioprotective tocopherol analogs
US5500444A (en) 1989-11-14 1996-03-19 Hoechst Marion Roussel, Inc. Cardioprotective tocopherol analogs
US5135945A (en) 1991-06-05 1992-08-04 Merrell Dow Pharmaceuticals Inc. Cholesterol-lowering tocopherol analogs

Also Published As

Publication number Publication date
ZA927429B (en) 1993-04-07
IL103305A0 (en) 1993-02-21
AU652077B2 (en) 1994-08-11
NO923840D0 (no) 1992-10-01
NZ244549A (en) 1994-07-26
HUT62592A (en) 1993-05-28
DE69224501D1 (de) 1998-04-02
ATE163421T1 (de) 1998-03-15
FI924424L (fi) 1993-04-03
FI105552B (fi) 2000-09-15
EP0536036A1 (en) 1993-04-07
HU9203134D0 (en) 1992-12-28
EP0535283A1 (en) 1993-04-07
CA2079289A1 (en) 1993-04-03
JPH05310763A (ja) 1993-11-22
HU215123B (hu) 1998-09-28
EP0536036B1 (en) 1998-02-25
KR100253108B1 (ko) 2000-05-01
NO923840L (no) 1993-04-05
CA2079289C (en) 2003-02-18
JP3230699B2 (ja) 2001-11-19
GR3026242T3 (en) 1998-05-29
ES2115656T3 (es) 1998-07-01
AU2538392A (en) 1993-04-08
DE69224501T2 (de) 1998-06-25
FI924424A0 (fi) 1992-10-01
TW224970B (cs) 1994-06-11

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