DK0528968T3 - 3- (3-Alkylthiopropyl) benzothiazoline derivatives, their preparation and drugs containing them - Google Patents

3- (3-Alkylthiopropyl) benzothiazoline derivatives, their preparation and drugs containing them

Info

Publication number
DK0528968T3
DK0528968T3 DK91910359.8T DK91910359T DK0528968T3 DK 0528968 T3 DK0528968 T3 DK 0528968T3 DK 91910359 T DK91910359 T DK 91910359T DK 0528968 T3 DK0528968 T3 DK 0528968T3
Authority
DK
Denmark
Prior art keywords
preparation
alkylthiopropyl
drugs containing
benzothiazoline derivatives
benzothiazoline
Prior art date
Application number
DK91910359.8T
Other languages
Danish (da)
Inventor
Claude Gueremy
Patrick Jimonet
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Application granted granted Critical
Publication of DK0528968T3 publication Critical patent/DK0528968T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Abstract

Compounds of formula (I), where R1? represents a polyfluoroalkoxy radical, and R2? represents an alkylthio, alkylsulphinyl or alkylsulphonyl radical, their salts, the preparation thereof, and drugs containing said compounds.
DK91910359.8T 1990-05-18 1991-05-15 3- (3-Alkylthiopropyl) benzothiazoline derivatives, their preparation and drugs containing them DK0528968T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9006277A FR2662160B1 (en) 1990-05-18 1990-05-18 ALKYLTHIO-3 PROPYL-3 BENZOTHIAZOLINE DERIVATIVES, THEIR PREPARATION AND THE MEDICINAL PRODUCTS CONTAINING THEM.

Publications (1)

Publication Number Publication Date
DK0528968T3 true DK0528968T3 (en) 1994-05-09

Family

ID=9396778

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91910359.8T DK0528968T3 (en) 1990-05-18 1991-05-15 3- (3-Alkylthiopropyl) benzothiazoline derivatives, their preparation and drugs containing them

Country Status (9)

Country Link
EP (1) EP0528968B1 (en)
JP (1) JPH05507272A (en)
AT (1) ATE101139T1 (en)
CA (1) CA2074833A1 (en)
DE (1) DE69101145T2 (en)
DK (1) DK0528968T3 (en)
ES (1) ES2062794T3 (en)
FR (1) FR2662160B1 (en)
WO (1) WO1991017984A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2688138B1 (en) * 1992-03-06 1995-05-05 Rhone Poulenc Rorer Sa APPLICATION OF AMINO-2 TRIFLUOROMETHOXY-6 BENZOTHIAZOLE TO OBTAIN A MEDICINE FOR THE TREATMENT OF AMYOTROPHIC LATERAL SCLEROSIS.
FR2700116B1 (en) * 1993-01-07 1995-02-03 Rhone Poulenc Rorer Sa Application of anti-convulsants as radioprotective agents.
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
HUP0001062A3 (en) 1996-09-27 2001-09-28 Guilford Pharmaceuticals Inc B Pharmaceutical compositions of phosphinic acid derivatives having naaladase inhibitor acivity

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2834852A1 (en) * 1978-08-09 1980-02-21 Hoechst Ag 2-Amino-or 2-imino-aryleno-thiazole cpds. prepn. - by cyclising thiourea derivs. with thionyl chloride
FR2492258A1 (en) * 1980-10-17 1982-04-23 Pharmindustrie NEW AMINO-2 TRIFLUOROMETHOXY-6 BENZOTHIAZOLE-BASED MEDICINAL PRODUCT
US4826860A (en) * 1987-03-16 1989-05-02 Warner-Lambert Company Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents
FR2619713B1 (en) * 1987-08-25 1990-08-31 Rhone Poulenc Sante APPLICATION OF AMINO-2 TRIFLUOROMETHOXY-6 BENZOTHIAZOLE TO OBTAIN MEDICINE FOR THE TREATMENT OF SLEEP AND DEPRESSION DISORDERS
FR2619712B1 (en) * 1987-08-25 1990-08-31 Rhone Poulenc Sante APPLICATION OF AMINO-2 TRIFLUOROMETHOXY-6 BENZOTHIAZOLE TO OBTAIN A MEDICINE FOR THE TREATMENT OF SCHIZOPHRENIA

Also Published As

Publication number Publication date
CA2074833A1 (en) 1991-11-19
FR2662160A1 (en) 1991-11-22
EP0528968B1 (en) 1994-02-02
DE69101145D1 (en) 1994-03-17
EP0528968A1 (en) 1993-03-03
DE69101145T2 (en) 1994-05-26
WO1991017984A1 (en) 1991-11-28
ATE101139T1 (en) 1994-02-15
JPH05507272A (en) 1993-10-21
ES2062794T3 (en) 1994-12-16
FR2662160B1 (en) 1992-07-24

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