DK0519950T3 - Preparation - Google Patents

Preparation

Info

Publication number
DK0519950T3
DK0519950T3 DK91905284.5T DK91905284T DK0519950T3 DK 0519950 T3 DK0519950 T3 DK 0519950T3 DK 91905284 T DK91905284 T DK 91905284T DK 0519950 T3 DK0519950 T3 DK 0519950T3
Authority
DK
Denmark
Prior art keywords
drug
preparation
ion
pharmaceutically acceptable
particle size
Prior art date
Application number
DK91905284.5T
Other languages
Danish (da)
Inventor
Timothy James Grattan
Original Assignee
Beecham Group Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group Plc filed Critical Beecham Group Plc
Application granted granted Critical
Publication of DK0519950T3 publication Critical patent/DK0519950T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A61K47/585—Ion exchange resins, e.g. polystyrene sulfonic acid resin

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Confectionery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

A composition for controlled and sustained release of a pharmaceutically acceptable drug comprising a drug-resin complex formed from an ion-exchange resin and a pharmacologically active drug, characterised in that at least 20 % by weight of the resinate particles have a particle size below 35 mu m.
DK91905284.5T 1990-03-12 1991-03-04 Preparation DK0519950T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB909005498A GB9005498D0 (en) 1990-03-12 1990-03-12 Composition

Publications (1)

Publication Number Publication Date
DK0519950T3 true DK0519950T3 (en) 1995-04-10

Family

ID=10672453

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91905284.5T DK0519950T3 (en) 1990-03-12 1991-03-04 Preparation

Country Status (14)

Country Link
EP (1) EP0519950B1 (en)
JP (1) JPH05504574A (en)
AT (1) ATE117893T1 (en)
AU (1) AU643263B2 (en)
CA (1) CA2077994A1 (en)
DE (1) DE69107202T2 (en)
DK (1) DK0519950T3 (en)
ES (1) ES2069880T3 (en)
GB (1) GB9005498D0 (en)
GR (1) GR3015821T3 (en)
HK (1) HK1004529A1 (en)
IE (1) IE65123B1 (en)
WO (1) WO1991013612A1 (en)
ZA (1) ZA911720B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9402029D0 (en) * 1994-02-03 1994-03-30 Smithkline Beecham Plc Novel formulation
US6548084B2 (en) 1995-07-20 2003-04-15 Smithkline Beecham Plc Controlled release compositions
WO1998027961A2 (en) * 1996-12-20 1998-07-02 Warner Lambert Company Antitussive drugs delivered by partially coated ion exchange resins
WO2000018374A1 (en) 1998-10-01 2000-04-06 Elan Pharma International, Ltd. Controlled release nanoparticulate compositions
EP1250937B1 (en) * 2001-04-09 2009-05-13 Rohm And Haas Company Controlled dissolution of active ingredients
US9149440B2 (en) 2003-09-02 2015-10-06 University Of South Florida Nanoparticles for drug-delivery
US20050238695A1 (en) * 2004-04-27 2005-10-27 Atma Chaudhari Lozenge for delivery of dextromethorphan
US8313770B2 (en) * 2007-05-30 2012-11-20 Neos Therapeutics, Lp Modifying drug release in suspensions of ionic resin systems
US20130190299A1 (en) 2010-06-30 2013-07-25 Victoria Link Ltd. Methods and compositions for treatment of multiple sclerosis
WO2017017699A1 (en) 2015-07-27 2017-02-02 Sun Pharma Advanced Research Company Limited Drug loaded nanoresin particles
WO2021071902A1 (en) * 2019-10-10 2021-04-15 Brillian Pharma Inc. Micronized drug resinate-based pharmaceutical compositions and methods of preparation thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2990332A (en) * 1958-04-02 1961-06-27 Wallace & Tiernan Inc Pharmaceutical preparations comprising cation exchange resin adsorption compounds and treatment therewith
US4221778A (en) * 1979-01-08 1980-09-09 Pennwalt Corporation Prolonged release pharmaceutical preparations
US4788055A (en) * 1985-12-09 1988-11-29 Ciba-Geigy Corporation Resinate sustained release dextromethorphan composition
US4894239A (en) * 1987-06-02 1990-01-16 Takeda Chemical Industries, Ltd. Sustained-release preparation and production thereof
US4996047A (en) * 1988-11-02 1991-02-26 Richardson-Vicks, Inc. Sustained release drug-resin complexes

Also Published As

Publication number Publication date
EP0519950A1 (en) 1992-12-30
WO1991013612A1 (en) 1991-09-19
ATE117893T1 (en) 1995-02-15
ZA911720B (en) 1992-02-26
AU643263B2 (en) 1993-11-11
ES2069880T3 (en) 1995-05-16
HK1004529A1 (en) 1998-11-27
DE69107202T2 (en) 1995-05-24
GR3015821T3 (en) 1995-07-31
EP0519950B1 (en) 1995-02-01
AU7348391A (en) 1991-10-10
DE69107202D1 (en) 1995-03-16
IE65123B1 (en) 1995-10-04
JPH05504574A (en) 1993-07-15
CA2077994A1 (en) 1991-09-13
IE910797A1 (en) 1991-09-25
GB9005498D0 (en) 1990-05-09

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