DK0424351T3 - Anvendelse af modificeret heparin-cofaktor II - Google Patents

Anvendelse af modificeret heparin-cofaktor II

Info

Publication number
DK0424351T3
DK0424351T3 DK90870188.1T DK90870188T DK0424351T3 DK 0424351 T3 DK0424351 T3 DK 0424351T3 DK 90870188 T DK90870188 T DK 90870188T DK 0424351 T3 DK0424351 T3 DK 0424351T3
Authority
DK
Denmark
Prior art keywords
heparin cofactor
modified heparin
hcii
modified
cofactor
Prior art date
Application number
DK90870188.1T
Other languages
English (en)
Inventor
Douglas Meyer Tollefsen
Vivianna Maia Derechin
Morey Alan Blinder
Original Assignee
Univ Washington
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington filed Critical Univ Washington
Application granted granted Critical
Publication of DK0424351T3 publication Critical patent/DK0424351T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81—Protease inhibitors
    • C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8121—Serpins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK90870188.1T 1989-10-20 1990-10-15 Anvendelse af modificeret heparin-cofaktor II DK0424351T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/424,440 US5102995A (en) 1989-10-20 1989-10-20 Dna encoding modified heparin cofactor ii

Publications (1)

Publication Number Publication Date
DK0424351T3 true DK0424351T3 (da) 1997-10-13

Family

ID=23682642

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90870188.1T DK0424351T3 (da) 1989-10-20 1990-10-15 Anvendelse af modificeret heparin-cofaktor II

Country Status (9)

Country Link
US (1) US5102995A (da)
EP (1) EP0424351B1 (da)
JP (1) JPH03139280A (da)
AT (1) ATE154388T1 (da)
CA (1) CA2028082A1 (da)
DE (1) DE69030909T2 (da)
DK (1) DK0424351T3 (da)
ES (1) ES2104598T3 (da)
GR (1) GR3024588T3 (da)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5871956A (en) * 1984-12-06 1999-02-16 Amgen Inc. Recombinant methods for production of serine inhibitors and DNA sequences useful for same
US6291662B1 (en) 1984-12-05 2001-09-18 Amgen Inc. Recombinant methods for production of serine protease inhibitors and DNA sequences
US6132990A (en) * 1984-12-06 2000-10-17 Amgen Boulder Inc. Recombinant methods for production of serine protease inhibitors and DNA sequences useful for same
US5900400A (en) * 1984-12-06 1999-05-04 Amgen Inc. Serine protease inhibitor analogs
GB9024685D0 (en) * 1990-11-13 1991-01-02 Raleigh Industries Ltd Cycle seat pillar mounting
JP3479539B2 (ja) * 1992-04-10 2003-12-15 エーザイ株式会社 ヒトアンチトロンビンｉｉｉ変異体
US6303691B1 (en) 1992-07-31 2001-10-16 Exxon Mobil Chemical Patents Inc. Impact modification of polyamides
US6869925B1 (en) * 1992-09-09 2005-03-22 Amgen Inc. Inhibition of retrovirus infection
US6017880A (en) * 1994-03-09 2000-01-25 Amgen Inc. Inhibition of retrovirus infection
JPH09176040A (ja) * 1995-12-27 1997-07-08 Green Cross Corp:The ヘパリンコファクターｉｉの医薬用途
WO1999043810A1 (en) * 1998-02-27 1999-09-02 The University Of North Carolina At Chapel Hill Mutant heparin cofactor ii
WO1999045953A1 (fr) * 1998-03-09 1999-09-16 Welfide Corporation Compositions contenant un cofacteur ii de l'heparine et techniques de stabilisation
GB0916578D0 (en) * 2009-09-22 2009-10-28 Malmsten Nils M Polypeptides and uses thereof
GB2500184A (en) * 2012-03-12 2013-09-18 Ximmune Ab Polypeptide derived from helix A of heparin cofactor II
US20180078916A1 (en) * 2015-03-18 2018-03-22 Carnegie Mellon University Lignin-based surfactants

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3521226A1 (de) * 1985-02-08 1986-08-14 Hoechst Ag, 6230 Frankfurt Gene fuer biologisch aktive proteine
US4861865A (en) * 1989-01-23 1989-08-29 Washington University Novel antithrombin peptide

Also Published As

Publication number Publication date
GR3024588T3 (en) 1997-12-31
EP0424351A2 (en) 1991-04-24
JPH03139280A (ja) 1991-06-13
US5102995A (en) 1992-04-07
EP0424351B1 (en) 1997-06-11
CA2028082A1 (en) 1991-04-21
ES2104598T3 (es) 1997-10-16
DE69030909D1 (de) 1997-07-17
DE69030909T2 (de) 1998-01-29
ATE154388T1 (de) 1997-06-15
EP0424351A3 (en) 1991-10-09

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