DK0419215T3 - Fremgangsmåde til fremstilling af 4-substituerede azetidioner - Google Patents

Fremgangsmåde til fremstilling af 4-substituerede azetidioner

Info

Publication number
DK0419215T3
DK0419215T3 DK90310206.9T DK90310206T DK0419215T3 DK 0419215 T3 DK0419215 T3 DK 0419215T3 DK 90310206 T DK90310206 T DK 90310206T DK 0419215 T3 DK0419215 T3 DK 0419215T3
Authority
DK
Denmark
Prior art keywords
substituted
azetid
ions
preparation
beta
Prior art date
Application number
DK90310206.9T
Other languages
Danish (da)
English (en)
Inventor
David Alfred Hall Jr
John Michael Morin Jr
Robert John Ternansky
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK0419215T3 publication Critical patent/DK0419215T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/085—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
    • C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Electrolytic Production Of Non-Metals, Compounds, Apparatuses Therefor (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK90310206.9T 1989-09-20 1990-09-18 Fremgangsmåde til fremstilling af 4-substituerede azetidioner DK0419215T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/410,173 US4992545A (en) 1989-09-20 1989-09-20 Process for preparing 4-substituted azetidinones

Publications (1)

Publication Number Publication Date
DK0419215T3 true DK0419215T3 (da) 1996-08-26

Family

ID=23623551

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90310206.9T DK0419215T3 (da) 1989-09-20 1990-09-18 Fremgangsmåde til fremstilling af 4-substituerede azetidioner

Country Status (13)

Country Link
US (1) US4992545A (fr)
EP (1) EP0419215B1 (fr)
JP (1) JPH03167170A (fr)
KR (1) KR910006228A (fr)
AT (1) ATE140697T1 (fr)
CA (1) CA2025517A1 (fr)
DE (1) DE69027900T2 (fr)
DK (1) DK0419215T3 (fr)
ES (1) ES2088979T3 (fr)
GR (1) GR3021309T3 (fr)
HU (1) HUT57188A (fr)
IE (1) IE74853B1 (fr)
IL (1) IL95714A (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5106475A (en) * 1989-09-20 1992-04-21 Eli Lilly And Company Process for preparing 4-substituted azetidinones
US5089610A (en) * 1991-04-25 1992-02-18 Eli Lilly And Company Ring-closure method for 1-carbacephalosporin six-membered ring
WO1994006764A1 (fr) * 1992-09-18 1994-03-31 Merck & Co., Inc. Preparation d'intermediaires de carbapeneme de beta-methyl

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7806860A (nl) * 1977-07-05 1979-01-09 Farmaceutici Italia Werkwijze voor het bereiden van met nocardicine verwan- te azetidinonen.
US4368156A (en) * 1981-03-09 1983-01-11 Eli Lilly And Company Preparation of 4-haloazetidin-2-ones from 4-sulfinoazetidin-2-ones
AU549269B2 (en) * 1981-11-30 1986-01-23 E.R. Squibb & Sons, Inc. 3-acylamino-4-sulfonyl-2-azetidinones
US4421686A (en) * 1981-11-30 1983-12-20 E. R. Squibb & Sons, Inc. 4-Norbornyl-sulfonyl azetidinone intermediates and process for preparing (S)-3-acylamino-4-substituted-2-azetidinones
HU190404B (en) * 1982-07-30 1986-09-29 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for preparing amino-lactone-carboxylic acid
US4652651A (en) * 1983-05-31 1987-03-24 Hoffmann-La Roche Inc. Process for the manufacture of 1-sulpho-2-oxoazetidine carboxylic acid intermediates via catalytic ester cleavage
DE3340006A1 (de) * 1983-11-04 1985-05-23 Hans Rudolf Prof. Dipl.-Chem. Dr. 8000 München Pfaendler Verfahren zur herstellung von azetidin-2-onen
US4771135A (en) * 1984-05-22 1988-09-13 Eli Lilly And Company Process for carbon-carbon bond formation at the C-4 position of 3-acylaminoazetidinones and products and starting materials therefor
EP0163452A1 (fr) * 1984-05-22 1985-12-04 Eli Lilly And Company Procédé pour la formation d'une liaison carbone-carbone en position C-4 d'acyl-3 amino-azétidinones
US4588484A (en) * 1985-02-28 1986-05-13 Eli Lilly And Company Electrochemical reduction of 3-chlorobenzo[b]thiophenes
US4665171A (en) * 1985-07-17 1987-05-12 Harvard University Process and intermediates for β-lactam antibiotics
US4960879A (en) * 1988-03-23 1990-10-02 Shionogi & Co., Ltd. Process for carbapenem intermediates

Also Published As

Publication number Publication date
KR910006228A (ko) 1991-04-27
ES2088979T3 (es) 1996-10-01
GR3021309T3 (en) 1997-01-31
JPH03167170A (ja) 1991-07-19
EP0419215B1 (fr) 1996-07-24
HU905971D0 (en) 1991-03-28
EP0419215A3 (en) 1992-04-08
CA2025517A1 (fr) 1991-03-21
HUT57188A (en) 1991-11-28
DE69027900D1 (de) 1996-08-29
IL95714A (en) 1994-07-31
IL95714A0 (en) 1991-06-30
DE69027900T2 (de) 1997-01-02
IE74853B1 (en) 1997-08-13
IE903392A1 (en) 1991-04-10
ATE140697T1 (de) 1996-08-15
EP0419215A2 (fr) 1991-03-27
US4992545A (en) 1991-02-12

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