DK0417745T3 - Heteroaryl-substituted imidazo (4,5-c) pyridines - Google Patents

Heteroaryl-substituted imidazo (4,5-c) pyridines

Info

Publication number
DK0417745T3
DK0417745T3 DK90117520.8T DK90117520T DK0417745T3 DK 0417745 T3 DK0417745 T3 DK 0417745T3 DK 90117520 T DK90117520 T DK 90117520T DK 0417745 T3 DK0417745 T3 DK 0417745T3
Authority
DK
Denmark
Prior art keywords
pyridines
heteroaryl
substituted imidazo
substituted
relates
Prior art date
Application number
DK90117520.8T
Other languages
Danish (da)
Inventor
Ish K Khanna
Richard Mathias Weier
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Application granted granted Critical
Publication of DK0417745T3 publication Critical patent/DK0417745T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Abstract

This invention relates to substituted imidazopyridine derivatives having the following formula <CHEM> useful in the treatment of diseases or disorders mediated by platelet-activating factor. This invention also relates to pharmaceutical compositions of such substituted imidazopyridines.
DK90117520.8T 1989-09-13 1990-09-11 Heteroaryl-substituted imidazo (4,5-c) pyridines DK0417745T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/406,674 US4990518A (en) 1989-09-13 1989-09-13 Pharmacologically active heteroaryl substituted imidazo (4,5-c) pyridines

Publications (1)

Publication Number Publication Date
DK0417745T3 true DK0417745T3 (en) 1993-12-13

Family

ID=23608994

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90117520.8T DK0417745T3 (en) 1989-09-13 1990-09-11 Heteroaryl-substituted imidazo (4,5-c) pyridines

Country Status (10)

Country Link
US (1) US4990518A (en)
EP (1) EP0417745B1 (en)
JP (1) JPH03109386A (en)
AT (1) ATE96795T1 (en)
CA (1) CA2025084A1 (en)
DE (1) DE69004389T2 (en)
DK (1) DK0417745T3 (en)
ES (1) ES2059942T3 (en)
IE (1) IE903314A1 (en)
PT (1) PT95296A (en)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5208242A (en) * 1992-08-26 1993-05-04 G. D. Searle & Co. 5-substituted-4-phenyl-5H-imidazo[4,5-c]pyridine derivatives
US5635514A (en) * 1994-10-25 1997-06-03 G. D. Searle & Company Heteroaralkyl and heteroarylthioalkyl thiophenolic compounds as 5-lipoxgenase inhibitors
WO2002053544A1 (en) * 2000-12-29 2002-07-11 Darwin Discovery Ltd. Pharmaceutical uses and synthesis of nicotinanilide-n-oxides
GB0215293D0 (en) 2002-07-03 2002-08-14 Rega Foundation Viral inhibitors
JP4970048B2 (en) * 2003-12-22 2012-07-04 カトリーケ・ウニフェルジテイト・ルーベン・カー・イュー・ルーベン・アール・アンド・ディ Imidazo [4,5-c] pyridine compounds and methods of antiviral therapy
JP5014129B2 (en) * 2004-07-27 2012-08-29 ギリアード サイエンシーズ， インコーポレイテッド Imidazo [4,5-d] pyrimidines, their use and methods of preparation
PL1841765T3 (en) * 2004-12-21 2009-08-31 Gilead Sciences Inc Imidazo[4,5-c]pyridine compound and method of antiviral treatment
ES2339298T3 (en) * 2006-07-07 2010-05-18 Gilead Sciences, Inc. PIRIDAZINE NOVEDOUS COMPOUND AND USE OF IT.
UA99466C2 (en) 2007-07-06 2012-08-27 Гилиад Сайенсиз, Инк. Crystalline pyridazine compound

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4281005A (en) * 1979-03-05 1981-07-28 Merck & Co., Inc. Novel 2-pyridylimidazole compounds
DE2927987A1 (en) * 1979-07-11 1981-02-05 Thomae Gmbh Dr K NEW 2-ALKOXYPHENYL-IMIDAZO ANGLE CLAMP ON 4.5-B ANGLE CLAMP ON PYRIDINE, THEIR PRODUCTION AND THE USE THEREOF AS MEDICINAL PRODUCTS
AT382377B (en) * 1985-04-27 1987-02-25 Beecham Group Plc METHOD FOR PRODUCING NEW 7-SUBSTITUTED AMINOPYRAZOLO (4,3-B) PYRIDINES
US4804658A (en) * 1986-09-15 1989-02-14 G. D. Searle & Co. Imidazopyridine derivatives and pharmaceutical compositions
MY104933A (en) * 1987-09-30 1994-07-30 Pfizer Ltd Platelet activating factor antagonists
US4914108A (en) * 1988-03-14 1990-04-03 G. D. Searle & Co. 5-substituted(4,5-c)imidazopyridine compounds which have useful platelet activating factor antagonistic activity
US5019581A (en) * 1988-03-14 1991-05-28 G. D. Searle & Co. 5-substituted (4,5-c) imidazopyridine compounds which have useful platelet activating factor antagonistic activity

Also Published As

Publication number Publication date
CA2025084A1 (en) 1991-03-14
EP0417745B1 (en) 1993-11-03
ATE96795T1 (en) 1993-11-15
IE903314A1 (en) 1991-04-10
EP0417745A3 (en) 1991-11-06
EP0417745A2 (en) 1991-03-20
US4990518A (en) 1991-02-05
JPH03109386A (en) 1991-05-09
DE69004389D1 (en) 1993-12-09
PT95296A (en) 1991-05-22
DE69004389T2 (en) 1994-03-24
ES2059942T3 (en) 1994-11-16

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