DK0403458T3 - Novel polypeptides and their use - Google Patents

Novel polypeptides and their use

Info

Publication number
DK0403458T3
DK0403458T3 DK90850228.9T DK90850228T DK0403458T3 DK 0403458 T3 DK0403458 T3 DK 0403458T3 DK 90850228 T DK90850228 T DK 90850228T DK 0403458 T3 DK0403458 T3 DK 0403458T3
Authority
DK
Denmark
Prior art keywords
lys
ile
ala
ser
gly
Prior art date
Application number
DK90850228.9T
Other languages
Danish (da)
Inventor
Hans Joernvall
Hans G Boman
Viktor Mutt
Jong-Youn Lee
Original Assignee
Hans G Boman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hans G Boman filed Critical Hans G Boman
Application granted granted Critical
Publication of DK0403458T3 publication Critical patent/DK0403458T3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Polypeptides having the aminoacid sequence: H2N-Ser-Try-Leu-Ser-Lys-Thr-Ala-Lys-Lys-Leu-Glu-Asn-Ser-Ala-Lys-Lys-Ar g-Ile-Ser- Glu-Gly-Ile-Ala-Ile-Ala-Ile-Gln-Gly-Gly-Pro-Arg-COOH, and functional derivatives thereof; pharmaceutical ccompositions containing such polypeptides; and a method of inhibiting bacterial growth.
DK90850228.9T 1989-06-16 1990-06-06 Novel polypeptides and their use DK0403458T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8902186A SE469132B (en) 1989-06-16 1989-06-16 POLYPEPTIDES AND PHARMACEUTICAL COMPOSITION CONTAINING THIS

Publications (1)

Publication Number Publication Date
DK0403458T3 true DK0403458T3 (en) 1994-01-10

Family

ID=20376306

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90850228.9T DK0403458T3 (en) 1989-06-16 1990-06-06 Novel polypeptides and their use

Country Status (8)

Country Link
US (1) US5096886A (en)
EP (1) EP0403458B1 (en)
JP (1) JP2856850B2 (en)
AT (1) ATE93527T1 (en)
CA (1) CA2018461C (en)
DE (1) DE69002881T2 (en)
DK (1) DK0403458T3 (en)
SE (1) SE469132B (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE468516B (en) * 1991-06-14 1993-02-01 Kabigen Ab NEW POLYPEPTIDES WHICH CAN BE OBTAINED FROM THE TIN GAS AND THEIR USE
US5847047A (en) * 1993-06-22 1998-12-08 E. I. Du Pont De Nemours And Company Antimicrobial composition of a polymer and a peptide forming amphiphilic helices of the magainin-type
US5856178A (en) * 1993-08-30 1999-01-05 Utah State University DNA cassettes for expression of lytic peptides in mammalian cells and transgenic organisms containing same
ATE280582T1 (en) * 1995-06-07 2004-11-15 Telik Inc METABOLIC EFFECTS OF CERTAIN GLUTATION ANALOGUES
US6010876A (en) * 1996-11-06 2000-01-04 The Regents Of The University Of California Clavanins
US6040293A (en) * 1996-11-06 2000-03-21 The Regents Of The University Of California Clavanins
US20020065397A1 (en) 2000-10-12 2002-05-30 Joseph Roberts Protecting therapeutic compositions from host-mediated inactivation
WO2010141135A2 (en) * 2009-03-05 2010-12-09 Trustees Of Boston University Bacteriophages expressing antimicrobial peptides and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4705777A (en) * 1985-02-25 1987-11-10 The Regents Of The University Of California Cationic oligopeptides having microbicidal activity
US4810777A (en) * 1987-03-04 1989-03-07 The United States Of America As Represented By The Department Of Health And Human Services Antimicrobial compounds
US4962277A (en) * 1988-12-09 1990-10-09 Scripps Clinic And Research Foundation Deletion analogues of magainin peptides

Also Published As

Publication number Publication date
EP0403458A1 (en) 1990-12-19
DE69002881D1 (en) 1993-09-30
CA2018461C (en) 2000-09-26
CA2018461A1 (en) 1990-12-16
SE8902186L (en) 1990-12-17
JPH03101698A (en) 1991-04-26
US5096886A (en) 1992-03-17
EP0403458B1 (en) 1993-08-25
ATE93527T1 (en) 1993-09-15
JP2856850B2 (en) 1999-02-10
DE69002881T2 (en) 1994-02-24
SE469132B (en) 1993-05-17

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