DK0395896T3 - Method for Separation of Toxins from Protein Solutions - Google Patents

Method for Separation of Toxins from Protein Solutions

Info

Publication number
DK0395896T3
DK0395896T3 DK90106334.7T DK90106334T DK0395896T3 DK 0395896 T3 DK0395896 T3 DK 0395896T3 DK 90106334 T DK90106334 T DK 90106334T DK 0395896 T3 DK0395896 T3 DK 0395896T3
Authority
DK
Denmark
Prior art keywords
toxins
separation
protein solutions
protein
solutions
Prior art date
Application number
DK90106334.7T
Other languages
Danish (da)
Inventor
Juergen Dr Roemisch
Norbert Prof Heimburger
Original Assignee
Behringwerke Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Behringwerke Ag filed Critical Behringwerke Ag
Application granted granted Critical
Publication of DK0395896T3 publication Critical patent/DK0395896T3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/18—Ion-exchange chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4721—Lipocortins

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A process for separating toxins from solutions of proteins is described and entails an aqueous solution of a protein which contains a buffer substance, a chelating agent and a detergent being subjected to ion exchange chromatography.
DK90106334.7T 1989-04-10 1990-04-03 Method for Separation of Toxins from Protein Solutions DK0395896T3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3911629A DE3911629A1 (en) 1989-04-10 1989-04-10 METHOD FOR SEPARATING TOXINES FROM PROTEIN SOLUTIONS

Publications (1)

Publication Number Publication Date
DK0395896T3 true DK0395896T3 (en) 1995-06-26

Family

ID=6378296

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90106334.7T DK0395896T3 (en) 1989-04-10 1990-04-03 Method for Separation of Toxins from Protein Solutions

Country Status (12)

Country Link
EP (1) EP0395896B1 (en)
JP (1) JP2833824B2 (en)
KR (1) KR900015783A (en)
AT (1) ATE118014T1 (en)
AU (1) AU641916B2 (en)
CA (1) CA2014222C (en)
DE (2) DE3911629A1 (en)
DK (1) DK0395896T3 (en)
ES (1) ES2068270T3 (en)
GR (1) GR3015579T3 (en)
IE (1) IE65260B1 (en)
PT (1) PT93704B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9019919D0 (en) * 1990-09-12 1990-10-24 Delta Biotechnology Ltd Purification of proteins
DE4003773A1 (en) * 1990-02-08 1991-08-14 Behringwerke Ag METHOD FOR PURIFYING LIPOCORTINES
US5063912A (en) * 1990-07-16 1991-11-12 Hughes John S Sleep inducing device
AUPM388494A0 (en) * 1994-02-16 1994-03-10 Csl Limited Process for removing endotoxins
DE19847074C1 (en) * 1998-10-06 2000-07-13 Chiron Behring Gmbh & Co Process for the removal of lipopolysaccharides from aqueous, protein-containing solutions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0286830A3 (en) * 1987-03-13 1990-01-24 BEHRINGWERKE Aktiengesellschaft Process for the extraction of protein pp4 from tissues, and the use of citric acid therefor
DE3724726A1 (en) * 1987-07-25 1989-02-02 Behringwerke Ag METHOD FOR PURIFYING THE PLACENTARY TISSUE PROTEIN PP4
US4981952A (en) * 1988-10-04 1991-01-01 Eli Lilly And Company Method for the purification of vitamin K-dependent proteins
DE4003773A1 (en) * 1990-02-08 1991-08-14 Behringwerke Ag METHOD FOR PURIFYING LIPOCORTINES

Also Published As

Publication number Publication date
KR900015783A (en) 1990-11-10
DE3911629A1 (en) 1990-10-11
EP0395896B1 (en) 1995-02-01
JP2833824B2 (en) 1998-12-09
IE901271L (en) 1990-10-10
AU641916B2 (en) 1993-10-07
PT93704A (en) 1990-11-20
CA2014222C (en) 2000-05-09
GR3015579T3 (en) 1995-06-30
EP0395896A3 (en) 1991-07-17
CA2014222A1 (en) 1990-10-10
ES2068270T3 (en) 1995-04-16
JPH02290899A (en) 1990-11-30
DE59008392D1 (en) 1995-03-16
ATE118014T1 (en) 1995-02-15
IE65260B1 (en) 1995-10-18
EP0395896A2 (en) 1990-11-07
PT93704B (en) 1997-12-31
AU5299290A (en) 1990-10-11

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